STRINGSTRING
RGL1 RGL1 RAB9A RAB9A RGL4 RGL4 RAPGEF5 RAPGEF5 ERAS ERAS RHOB RHOB RHOG RHOG RAPGEF2 RAPGEF2 LOC105464688 LOC105464688 RAB33A RAB33A RAPGEF3 RAPGEF3 CYFIP1 CYFIP1 ELMO1 ELMO1 RHOH RHOH CDKN1A CDKN1A RASGEF1A RASGEF1A DGKI DGKI CCNA2 CCNA2 PRKD1 PRKD1 PLD1 PLD1 RAB15 RAB15 SETDB1 SETDB1 CDC42EP3 CDC42EP3 RHOV RHOV C15orf62 C15orf62 RTKN RTKN RASGRP2 RASGRP2 USP8 USP8 SHTN1 SHTN1 ARHGAP6 ARHGAP6 RAB33B RAB33B RFXANK RFXANK CDC42EP2 CDC42EP2 SOS2 SOS2 PLK2 PLK2 RAP2B RAP2B ENSMNEP00000007269 ENSMNEP00000007269 CDC42EP5 CDC42EP5 LOC105480640 LOC105480640 ABI2 ABI2 RALGPS1 RALGPS1 NTN1 NTN1 TAX1BP3 TAX1BP3 ARHGEF1 ARHGEF1 RALA RALA ENSMNEP00000009362 ENSMNEP00000009362 GDI1 GDI1 KSR1 KSR1 DNMT1 DNMT1 WASF1 WASF1 RASGRF2 RASGRF2 NF1 NF1 MRAS MRAS ENSMNEP00000010524 ENSMNEP00000010524 ITGA3 ITGA3 RAPGEF1 RAPGEF1 NCKAP1 NCKAP1 ARHGAP35 ARHGAP35 RASSF1 RASSF1 FARP2 FARP2 PARK7 PARK7 RB1 RB1 ENSMNEP00000012161 ENSMNEP00000012161 CNKSR1 CNKSR1 HACE1 HACE1 RAB39B RAB39B PLEKHG7 PLEKHG7 PLCE1 PLCE1 RAPGEF4 RAPGEF4 ENSMNEP00000013458 ENSMNEP00000013458 DOK3 DOK3 MAPKAPK5 MAPKAPK5 RAP1A RAP1A SGSM3 SGSM3 ZNF304 ZNF304 DOK1 DOK1 RIPOR1 RIPOR1 ARHGAP29 ARHGAP29 COL1A2 COL1A2 RRAS RRAS AGTR1 AGTR1 RAB42 RAB42 TMEM19 TMEM19 RASGRP1 RASGRP1 RAPGEFL1 RAPGEFL1 RAC2 RAC2 WASF2 WASF2 ENSMNEP00000019244 ENSMNEP00000019244 ADGRG1 ADGRG1 CRKL CRKL PHACTR4 PHACTR4 ARHGEF12 ARHGEF12 PPP1R21 PPP1R21 RASGRP3 RASGRP3 BCL6 BCL6 RHOD RHOD WAS WAS RAB4B RAB4B SYNJ2BP SYNJ2BP ENSMNEP00000021960 ENSMNEP00000021960 EPS8 EPS8 RANGRF RANGRF RASGRP4 RASGRP4 LAT LAT ENSMNEP00000025369 ENSMNEP00000025369 EPS8L3 EPS8L3 TRIM28 TRIM28 KRAS KRAS AIF1 AIF1 EPS8L1 EPS8L1 RAB39A RAB39A DOK2 DOK2 RAB30 RAB30 RAP2A RAP2A LOC105496925 LOC105496925 ENSMNEP00000028359 ENSMNEP00000028359 CSF1 CSF1 RAB21 RAB21 ROCK1 ROCK1 RIT2 RIT2 NKIRAS2 NKIRAS2 ENSMNEP00000030256 ENSMNEP00000030256 SYNGAP1 SYNGAP1 ENSMNEP00000030578 ENSMNEP00000030578 CELSR1 CELSR1 ENSMNEP00000031174 ENSMNEP00000031174 RGL2 RGL2 ENSMNEP00000031282 ENSMNEP00000031282 HRAS HRAS BRAP BRAP SDCBP SDCBP ENSMNEP00000032418 ENSMNEP00000032418 RIT1 RIT1 EPS8L2 EPS8L2 ARHGAP4 ARHGAP4 GNA12 GNA12 GNA13 GNA13 ENSMNEP00000034090 ENSMNEP00000034090 ENSMNEP00000034131 ENSMNEP00000034131 ENSMNEP00000034429 ENSMNEP00000034429 RRAS2 RRAS2 RHOJ RHOJ RAB12 RAB12 RAP1B RAP1B KPNB1 KPNB1 CDC42EP1 CDC42EP1 LIMK1 LIMK1 NISCH NISCH GPSM2 GPSM2 KITLG KITLG RHOA RHOA ARHGEF11 ARHGEF11 RERG RERG BRK1 BRK1 RHOU RHOU ENSMNEP00000039571 ENSMNEP00000039571 RALB RALB ENSMNEP00000039987 ENSMNEP00000039987 KIAA0355 KIAA0355 KSR2 KSR2 NGFR NGFR ARHGDIG ARHGDIG RABGEF1 RABGEF1 RAB35 RAB35 USP28 USP28 PDPN PDPN DBNL DBNL GRAP GRAP IQGAP3 IQGAP3 ARHGAP1 ARHGAP1 SOS1 SOS1 GRAP2 GRAP2 RACGAP1 RACGAP1 ROCK2 ROCK2 CDK2 CDK2 RAP2C RAP2C PLEKHG5 PLEKHG5 ARHGAP5 ARHGAP5 RASGRF1 RASGRF1 RALGDS RALGDS MYO9B MYO9B NRAS NRAS TIAM1 TIAM1 RAB4A RAB4A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RGL1Ral guanine nucleotide dissociation stimulator like 1. (803 aa)
RAB9ARAB9A, member RAS oncogene family. (201 aa)
RGL4Ral guanine nucleotide dissociation stimulator like 4. (471 aa)
RAPGEF5Rap guanine nucleotide exchange factor 5. (883 aa)
ERASES cell expressed Ras. (233 aa)
RHOBRas homolog family member B. (196 aa)
RHOGUncharacterized protein. (191 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1701 aa)
LOC105464688Ras-GEF domain-containing protein. (387 aa)
RAB33ARAB33A, member RAS oncogene family. (237 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (878 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
RHOHUncharacterized protein. (191 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
RASGEF1ARasGEF domain family member 1A. (489 aa)
DGKIDiacylglycerol kinase. (1079 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (892 aa)
PLD1Phospholipase. (1074 aa)
RAB15RAB15, member RAS oncogene family. (212 aa)
SETDB1SET domain bifurcated histone lysine methyltransferase 1. (1291 aa)
CDC42EP3CDC42 effector protein 3. (254 aa)
RHOVRas homolog family member V. (240 aa)
C15orf62Chromosome 15 open reading frame 62. (175 aa)
RTKNRhotekin. (563 aa)
RASGRP2RAS guanyl releasing protein 2. (771 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1082 aa)
SHTN1Shootin 1. (636 aa)
ARHGAP6Rho GTPase activating protein 6. (977 aa)
RAB33BRAB33B, member RAS oncogene family. (229 aa)
RFXANKRegulatory factor X associated ankyrin containing protein. (260 aa)
CDC42EP2Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family. (210 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
RAP2BRAP2B, member of RAS oncogene family. (183 aa)
ENSMNEP00000007269VPS9 domain-containing protein. (363 aa)
CDC42EP5CDC42 effector protein 5. (148 aa)
LOC105480640Ras-GEF domain-containing protein. (429 aa)
ABI2Abl interactor 2. (513 aa)
RALGPS1Ral GEF with PH domain and SH3 binding motif 1. (658 aa)
NTN1Netrin 1. (604 aa)
TAX1BP3Tax1-binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. (124 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (972 aa)
RALARAS like proto-oncogene A. (206 aa)
ENSMNEP00000009362Ras-GEF domain-containing protein. (509 aa)
GDI1Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (477 aa)
KSR1Kinase suppressor of ras 1. (932 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1712 aa)
WASF1WASP family member 1. (559 aa)
RASGRF2Ras protein specific guanine nucleotide releasing factor 2. (1237 aa)
NF1Neurofibromin 1. (2839 aa)
MRASMuscle RAS oncogene homolog. (208 aa)
ENSMNEP00000010524DJ-1_PfpI domain-containing protein. (186 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1064 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1265 aa)
NCKAP1NCK associated protein 1. (1134 aa)
ARHGAP35Rho GTPase activating protein 35. (1499 aa)
RASSF1Ras association domain family member 1. (340 aa)
FARP2FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1023 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
RB1RB transcriptional corepressor 1. (928 aa)
ENSMNEP00000012161Ras-GEF domain-containing protein. (530 aa)
CNKSR1Connector enhancer of kinase suppressor of Ras 1. (713 aa)
HACE1HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1. (909 aa)
RAB39BRAB39B, member RAS oncogene family. (213 aa)
PLEKHG7Chromosome 12 open reading frame 74. (531 aa)
PLCE1Phosphoinositide phospholipase C. (2295 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (1011 aa)
ENSMNEP00000013458PDZ domain-containing protein. (259 aa)
DOK3Docking protein 3. (467 aa)
MAPKAPK5MAPK activated protein kinase 5. (474 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
SGSM3Small G protein signaling modulator 3. (750 aa)
ZNF304Zinc finger protein 304. (706 aa)
DOK1Docking protein 1. (454 aa)
RIPOR1RHO family interacting cell polarization regulator 1. (1217 aa)
ARHGAP29Rho GTPase activating protein 29. (1266 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
RRASRAS related. (218 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
RAB42RAB42, member RAS oncogene family. (218 aa)
TMEM19Transmembrane protein 19. (336 aa)
RASGRP1RAS guanyl releasing protein 1. (832 aa)
RAPGEFL1Rap guanine nucleotide exchange factor like 1. (662 aa)
RAC2Rac family small GTPase 2. (192 aa)
WASF2WASP family member 2. (499 aa)
ENSMNEP00000019244Uncharacterized protein. (175 aa)
ADGRG1Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (624 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
PHACTR4Phosphatase and actin regulator. (720 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1484 aa)
PPP1R21Protein phosphatase 1 regulatory subunit 21. (780 aa)
RASGRP3RAS guanyl releasing protein 3. (734 aa)
BCL6BCL6 transcription repressor. (708 aa)
RHODRas homolog family member D. (210 aa)
WASWASP actin nucleation promoting factor. (545 aa)
RAB4BUncharacterized protein. (213 aa)
SYNJ2BPSynaptojanin 2 binding protein. (145 aa)
ENSMNEP00000021960Uncharacterized protein. (198 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (833 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
RASGRP4RAS guanyl releasing protein 4. (673 aa)
LATLinker for activation of T cells. (271 aa)
ENSMNEP00000025369Uncharacterized protein. (129 aa)
EPS8L3EPS8 like 3. (626 aa)
TRIM28Tripartite motif containing 28. (835 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
EPS8L1EPS8 like 1. (718 aa)
RAB39ARAB39A, member RAS oncogene family. (217 aa)
DOK2Docking protein 2. (412 aa)
RAB30RAB30, member RAS oncogene family. (203 aa)
RAP2ARAP2A, member of RAS oncogene family. (171 aa)
LOC105496925Rho-related GTP-binding protein RhoH. (191 aa)
ENSMNEP00000028359Uncharacterized protein. (39 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (555 aa)
RAB21RAB21, member RAS oncogene family. (223 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
RIT2Ras like without CAAX 2. (217 aa)
NKIRAS2NFKB inhibitor interacting Ras like 2. (228 aa)
ENSMNEP00000030256Uncharacterized protein. (210 aa)
SYNGAP1Synaptic Ras GTPase activating protein 1. (1328 aa)
ENSMNEP00000030578PDZ domain-containing protein. (262 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2773 aa)
ENSMNEP00000031174Uncharacterized protein. (182 aa)
RGL2Ral guanine nucleotide dissociation stimulator like 2. (777 aa)
ENSMNEP00000031282Uncharacterized protein. (1267 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
BRAPBRCA1 associated protein. (592 aa)
SDCBPSyndecan binding protein. (318 aa)
ENSMNEP00000032418DJ-1_PfpI domain-containing protein. (166 aa)
RIT1Ras like without CAAX 1. (219 aa)
EPS8L2EPS8 like 2. (756 aa)
ARHGAP4Rho GTPase activating protein 4. (946 aa)
GNA12G protein subunit alpha 12. (314 aa)
GNA13G protein subunit alpha 13. (377 aa)
ENSMNEP00000034090Ras-GEF domain-containing protein. (470 aa)
ENSMNEP00000034131DJ-1_PfpI domain-containing protein. (170 aa)
ENSMNEP00000034429Uncharacterized protein. (291 aa)
RRAS2RAS related 2. (204 aa)
RHOJRas homolog family member J. (214 aa)
RAB12RAB12, member RAS oncogene family. (259 aa)
RAP1BUncharacterized protein. (137 aa)
KPNB1Karyopherin subunit beta 1. (876 aa)
CDC42EP1CDC42 effector protein 1. (398 aa)
LIMK1LIM domain kinase 1. (677 aa)
NISCHNischarin. (1502 aa)
GPSM2G protein signaling modulator 2. (685 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
RHOARas homolog family member A. (193 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1562 aa)
RERGRAS like estrogen regulated growth inhibitor. (199 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
RHOURas homolog family member U. (258 aa)
ENSMNEP00000039571Uncharacterized protein. (136 aa)
RALBRAS like proto-oncogene B. (212 aa)
ENSMNEP00000039987Uncharacterized protein. (135 aa)
KIAA0355KIAA0355. (1070 aa)
KSR2Kinase suppressor of ras 2. (950 aa)
NGFRNerve growth factor receptor. (439 aa)
ARHGDIGRho GDP dissociation inhibitor gamma. (225 aa)
RABGEF1A20-type domain-containing protein. (469 aa)
RAB35RAB35, member RAS oncogene family. (201 aa)
USP28Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family. (1139 aa)
PDPNPodoplanin. (162 aa)
DBNLDrebrin like. (440 aa)
GRAPGRB2 related adaptor protein. (217 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1631 aa)
ARHGAP1Rho GTPase activating protein 1. (504 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1314 aa)
GRAP2GRB2 related adaptor protein 2. (330 aa)
RACGAP1Rac GTPase activating protein 1. (632 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1474 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
RAP2CRAP2C, member of RAS oncogene family. (183 aa)
PLEKHG5Pleckstrin homology and RhoGEF domain containing G5. (1066 aa)
ARHGAP5Rho GTPase activating protein 5. (1502 aa)
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1273 aa)
RALGDSUncharacterized protein. (909 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2135 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1577 aa)
RAB4AUncharacterized protein. (220 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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