STRINGSTRING
RNLS RNLS PTPRO PTPRO ABCC9 ABCC9 VEGFC VEGFC ENSMNEP00000044937 ENSMNEP00000044937 GCGR GCGR GRIP2 GRIP2 LRP5 LRP5 EXT1 EXT1 SERPINF2 SERPINF2 DDAH1 DDAH1 NAV2 NAV2 CHGA CHGA UTS2B UTS2B KCNQ1 KCNQ1 PTGS1 PTGS1 ADRA1D ADRA1D ADIPOQ ADIPOQ ANPEP ANPEP TAC3 TAC3 NPR3 NPR3 AVPR1B AVPR1B ATP2B1 ATP2B1 RHOA RHOA DRD2 DRD2 CALCA CALCA ADM ADM SCPEP1 SCPEP1 CARTPT CARTPT UMOD UMOD CD34 CD34 GCH1 GCH1 TAC1 TAC1 CYBA CYBA OXT OXT GNA13 GNA13 GNA12 GNA12 ABAT ABAT F2R F2R MKKS MKKS NPPB NPPB RASL10B RASL10B ID2 ID2 EDN3 EDN3 ENSMNEP00000031177 ENSMNEP00000031177 UTS2 UTS2 GSK3A GSK3A RENBP RENBP ACVRL1 ACVRL1 TRHDE TRHDE ACE2 ACE2 ADAMTS16 ADAMTS16 PDGFB PDGFB ADM5 ADM5 NPR1 NPR1 ERAP1 ERAP1 OXTR OXTR NPY NPY AVP AVP EDN2 EDN2 GAS6 GAS6 ADRB3 ADRB3 NPPA NPPA GNB3 GNB3 KCNK6 KCNK6 GUCY1A1 GUCY1A1 TNNI3 TNNI3 EMILIN1 EMILIN1 ENSMNEP00000025622 ENSMNEP00000025622 CTSZ CTSZ ATP1A2 ATP1A2 NOS1 NOS1 FSHR FSHR NR2F2 NR2F2 LNPEP LNPEP REN REN ENG ENG ATP1A1 ATP1A1 ADRA1B ADRA1B SLC4A5 SLC4A5 PPARA PPARA AVPR1A AVPR1A P2RX1 P2RX1 NPY1R NPY1R CTSG CTSG RAMP2 RAMP2 TACR3 TACR3 PTGS2 PTGS2 BBS4 BBS4 CPA3 CPA3 SMAD3 SMAD3 HSD11B2 HSD11B2 AGTR1 AGTR1 ENSMNEP00000017251 ENSMNEP00000017251 BMPR2 BMPR2 ENPEP ENPEP EMILIN2 EMILIN2 ADRA1A ADRA1A COL1A2 COL1A2 LOC105477045 LOC105477045 NDST2 NDST2 BDKRB1 BDKRB1 EMP2 EMP2 LOC105463814 LOC105463814 ACE ACE ECE1 ECE1 AGT AGT WNK1 WNK1 ADM2 ADM2 CYP11B1 CYP11B1 NTSR1 NTSR1 ADH5 ADH5 AR AR NPR2 NPR2 TAC4 TAC4 ADRB2 ADRB2 NOX1 NOX1 EDNRA EDNRA LVRN LVRN LOC105470579 LOC105470579 ATP6AP2 ATP6AP2 SOD1 SOD1 CORIN CORIN STK39 STK39 ADRB1 ADRB1 TACR1 TACR1 DRD5 DRD5 MECP2 MECP2 EXT2 EXT2 EDNRB EDNRB SPX SPX ADRA2B ADRA2B NOS3 NOS3 P2RX2 P2RX2 POMC POMC APLN APLN GJA5 GJA5 PCSK5 PCSK5 DLL1 DLL1 ENSMNEP00000006490 ENSMNEP00000006490 AGTR2 AGTR2 TRPV1 TRPV1 UTS2R UTS2R PLCB3 PLCB3 RPS6KA2 RPS6KA2 ARHGAP42 ARHGAP42 P2RX4 P2RX4 CORO2B CORO2B EDN1 EDN1 ENSMNEP00000008644 ENSMNEP00000008644 GPR37L1 GPR37L1 PDE4D PDE4D AVPR2 AVPR2 NCALD NCALD SUCNR1 SUCNR1 TBXA2R TBXA2R GLP1R GLP1R
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RNLSRenalase, FAD dependent amine oxidase. (342 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1216 aa)
ABCC9ATP binding cassette subfamily C member 9. (1524 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (421 aa)
ENSMNEP00000044937Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (297 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (491 aa)
GRIP2Glutamate receptor interacting protein 2. (1140 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1599 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (491 aa)
DDAH1Dimethylarginine dimethylaminohydrolase 1. (285 aa)
NAV2Neuron navigator 2. (2463 aa)
CHGAChromogranin A. (543 aa)
UTS2BUrotensin 2B. (118 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (632 aa)
ADRA1DAdrenoceptor alpha 1D. (570 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (274 aa)
ANPEPAminopeptidase. (968 aa)
TAC3Tachykinin 3. (121 aa)
NPR3Natriuretic peptide receptor 3. (541 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (424 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
RHOARas homolog family member A. (193 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
CALCACalcitonin related polypeptide alpha. (140 aa)
ADMAdrenomedullin. (185 aa)
SCPEP1Carboxypeptidase; Belongs to the peptidase S10 family. (452 aa)
CARTPTCART prepropeptide. (116 aa)
UMODUromodulin. (641 aa)
CD34CD34 molecule. (385 aa)
GCH1GTP cyclohydrolase 1. (249 aa)
TAC1Tachykinin precursor 1. (129 aa)
CYBACytochrome b-245 alpha chain. (197 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (125 aa)
GNA13G protein subunit alpha 13. (377 aa)
GNA12G protein subunit alpha 12. (314 aa)
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (501 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
NPPBNatriuretic peptide B. (132 aa)
RASL10BRAS like family 10 member B. (203 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
EDN3Endothelin 3. (211 aa)
ENSMNEP00000031177Uncharacterized protein. (220 aa)
UTS2Urotensin 2. (138 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
RENBPRenin binding protein. (431 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (528 aa)
TRHDEThyrotropin releasing hormone degrading enzyme. (1068 aa)
ACE2Angiotensin-converting enzyme. (805 aa)
ADAMTS16ADAM metallopeptidase with thrombospondin type 1 motif 16. (1246 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
ADM5Adrenomedullin 5 (putative). (141 aa)
NPR1Guanylate cyclase. (1061 aa)
ERAP1Aminopeptidase. (925 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (389 aa)
NPYNeuropeptide Y. (97 aa)
AVPArginine vasopressin; Belongs to the vasopressin/oxytocin family. (164 aa)
EDN2Endothelin 2. (206 aa)
GAS6Growth arrest specific 6. (683 aa)
ADRB3G_PROTEIN_RECEP_F1_2 domain-containing protein. (418 aa)
NPPANatriuretic peptide A. (153 aa)
GNB3G protein subunit beta 3. (340 aa)
KCNK6Potassium channel subfamily K member. (313 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
TNNI3Troponin I3, cardiac type. (210 aa)
EMILIN1Elastin microfibril interfacer 1. (1016 aa)
ENSMNEP00000025622Uncharacterized protein. (123 aa)
CTSZCathepsin Z; Belongs to the peptidase C1 family. (303 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1023 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa)
NR2F2Nuclear receptor subfamily 2 group F member 2. (414 aa)
LNPEPLeucyl and cystinyl aminopeptidase. (1027 aa)
RENRenin; Belongs to the peptidase A1 family. (406 aa)
ENGEndoglin. (658 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
ADRA1BAdrenoceptor alpha 1B. (518 aa)
SLC4A5Anion exchange protein. (1136 aa)
PPARAPeroxisome proliferator activated receptor alpha. (467 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (421 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
NPY1RNeuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family. (383 aa)
CTSGCathepsin G; Belongs to the peptidase S1 family. (255 aa)
RAMP2Receptor activity modifying protein 2. (175 aa)
TACR3Tachykinin receptor 3; Belongs to the G-protein coupled receptor 1 family. (463 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
BBS4Bardet-Biedl syndrome 4. (509 aa)
CPA3Carboxypeptidase A3. (417 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
HSD11B2Hydroxysteroid 11-beta dehydrogenase 2. (400 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
ENSMNEP00000017251Uncharacterized protein. (311 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
ENPEPAminopeptidase. (957 aa)
EMILIN2Elastin microfibril interfacer 2. (1049 aa)
ADRA1AAdrenoceptor alpha 1A. (466 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
LOC105477045S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)
NDST2Uncharacterized protein. (883 aa)
BDKRB1Bradykinin receptor B1. (282 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
LOC105463814Protein kinase domain-containing protein. (393 aa)
ACEAngiotensin-converting enzyme. (1160 aa)
ECE1Endothelin converting enzyme 1. (771 aa)
AGTAngiotensinogen; Belongs to the serpin family. (485 aa)
WNK1OSR1_C domain-containing protein. (2398 aa)
ADM2Adrenomedullin 2. (148 aa)
CYP11B1Cytochrome P450 family 11 subfamily B member 1; Belongs to the cytochrome P450 family. (572 aa)
NTSR1Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (418 aa)
ADH5S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)
ARAndrogen receptor. (898 aa)
NPR2Guanylate cyclase. (1047 aa)
TAC4Tachykinin 4. (79 aa)
ADRB2Adrenoceptor beta 2. (415 aa)
NOX1NADPH oxidase 1. (564 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
LVRNAminopeptidase. (990 aa)
LOC105470579Uncharacterized protein. (245 aa)
ATP6AP2ATPase H+ transporting accessory protein 2. (350 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
CORINCorin, serine peptidase. (1019 aa)
STK39Serine/threonine kinase 39. (550 aa)
ADRB1Adrenoceptor beta 1. (482 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
DRD5Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (478 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (751 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (516 aa)
SPXSpexin hormone. (116 aa)
ADRA2BAdrenoceptor alpha 2B. (445 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (496 aa)
POMCCorticotropin-like intermediary peptide; [Corticotropin]: Stimulates the adrenal glands to release cortisol. [Melanocyte-stimulating hormone beta]: Increases the pigmentation of skin by increasing melanin production in melanocytes. [Met-enkephalin]: Endogenous opiate; Belongs to the POMC family. (265 aa)
APLNApelin. (77 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1887 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
ENSMNEP00000006490Uncharacterized protein. (443 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (748 aa)
UTS2RUrotensin 2 receptor; Belongs to the G-protein coupled receptor 1 family. (389 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
RPS6KA2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (723 aa)
ARHGAP42Rho GTPase activating protein 42. (746 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (388 aa)
CORO2BCoronin; Belongs to the WD repeat coronin family. (494 aa)
EDN1Endothelin 1. (211 aa)
ENSMNEP00000008644Uncharacterized protein. (322 aa)
GPR37L1G protein-coupled receptor 37 like 1. (481 aa)
PDE4DPhosphodiesterase. (809 aa)
AVPR2Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (368 aa)
NCALDNeurocalcin delta. (193 aa)
SUCNR1Succinate receptor 1; Belongs to the G-protein coupled receptor 1 family. (325 aa)
TBXA2RThromboxane A2 receptor. (454 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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