STRINGSTRING
TERT TERT MYOCD MYOCD RPS6KB1 RPS6KB1 ABHD2 ABHD2 SORL1 SORL1 ITGA2 ITGA2 CORO1B CORO1B LPAR1 LPAR1 DOCK5 DOCK5 FOXO4 FOXO4 SLIT2 SLIT2 ADIPOQ ADIPOQ IL18 IL18 PPARD PPARD PDGFA PDGFA NDRG4 NDRG4 IGFBP3 IGFBP3 LOC105475951 LOC105475951 TLR4 TLR4 CCN4 CCN4 GNA13 GNA13 GNA12 GNA12 PLXNA1 PLXNA1 CRK CRK ENSMNEP00000032227 ENSMNEP00000032227 ADAMTS1 ADAMTS1 NR4A3 NR4A3 NRP1 NRP1 ENSMNEP00000029505 ENSMNEP00000029505 PDGFB PDGFB PLAU PLAU CYP1B1 CYP1B1 AIF1 AIF1 MEF2C MEF2C HAS2 HAS2 BCL2 BCL2 IGFBP5 IGFBP5 XBP1 XBP1 FGF9 FGF9 PDGFRB PDGFRB BMPR1A BMPR1A S100A11 S100A11 LRP1 LRP1 DOCK7 DOCK7 PRKG1 PRKG1 DOCK4 DOCK4 NF1 NF1 TRIB1 TRIB1 ITGB3 ITGB3 ENSMNEP00000008306 ENSMNEP00000008306 NFE2L2 NFE2L2 SERPINE1 SERPINE1 SRC SRC S1PR2 S1PR2 ENSMNEP00000005486 ENSMNEP00000005486 P2RY6 P2RY6 ATP7A ATP7A ENSMNEP00000003967 ENSMNEP00000003967 TACR1 TACR1 MDK MDK IGF1 IGF1 DDR2 DDR2 TAFA5 TAFA5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1132 aa)
MYOCDMyocardin. (986 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
ABHD2Abhydrolase domain containing 2. (452 aa)
SORL1Sortilin related receptor 1. (2184 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
CORO1BCoronin; Belongs to the WD repeat coronin family. (489 aa)
LPAR1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (366 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1860 aa)
FOXO4Forkhead box O4. (505 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (274 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
NDRG4NDRG family member 4. (391 aa)
IGFBP3Insulin like growth factor binding protein 3. (291 aa)
LOC105475951G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (378 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (826 aa)
CCN4Cellular communication network factor 4. (367 aa)
GNA13G protein subunit alpha 13. (377 aa)
GNA12G protein subunit alpha 12. (314 aa)
PLXNA1Plexin A1. (1907 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
ENSMNEP00000032227EF-hand domain-containing protein; Belongs to the S-100 family. (107 aa)
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif 1. (967 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (637 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (925 aa)
ENSMNEP00000029505Protein S100; Belongs to the S-100 family. (105 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
PLAUPlasminogen activator, urokinase. (429 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (542 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
MEF2CMyocyte enhancer factor 2C. (486 aa)
HAS2Hyaluronan synthase 2. (552 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
IGFBP5Insulin like growth factor binding protein 5. (272 aa)
XBP1BZIP domain-containing protein. (380 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
S100A11Protein S100; Belongs to the S-100 family. (105 aa)
LRP1LDL receptor related protein 1. (4544 aa)
DOCK7Dedicator of cytokinesis 7; Belongs to the DOCK family. (2131 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (2003 aa)
NF1Neurofibromin 1. (2839 aa)
TRIB1Tribbles pseudokinase 1. (372 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
ENSMNEP00000008306G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (368 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (618 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (379 aa)
SRCTyrosine-protein kinase. (644 aa)
S1PR2Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (353 aa)
ENSMNEP00000005486Protein S100; Belongs to the S-100 family. (104 aa)
P2RY6Pyrimidinergic receptor P2Y6. (328 aa)
ATP7AATPase copper transporting alpha. (1500 aa)
ENSMNEP00000003967Protein S100; Belongs to the S-100 family. (105 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
MDKMidkine. (168 aa)
IGF1Insulin like growth factor 1. (208 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (873 aa)
TAFA5TAFA chemokine like family member 5. (180 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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