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| | PIK3C2B | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1634 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (838 aa) |
| | AP4M1 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (454 aa) |
| | LRBA | LPS responsive beige-like anchor protein. (2852 aa) |
| | SQSTM1 | Sequestosome 1. (440 aa) |
| | GABARAPL2 | GABA type A receptor associated protein like 2. (117 aa) |
| | ENSMNEP00000004118 | Uncharacterized protein. (175 aa) |
| | ENSMNEP00000003819 | Uncharacterized protein. (322 aa) |
| | LOC105481479 | Uncharacterized protein. (115 aa) |
| | YOD1 | YOD1 deubiquitinase. (348 aa) |
| | VTI1B | Vesicle transport through interaction with t-SNAREs 1B. (232 aa) |
| | C5orf51 | Chromosome 5 open reading frame 51. (332 aa) |
| | ATG2B | Autophagy related 2B. (2078 aa) |
| | SNX14 | Sorting nexin 14. (946 aa) |
| | TP53INP2 | Tumor protein p53 inducible nuclear protein 2. (220 aa) |
| | UFL1 | UFM1 specific ligase 1. (793 aa) |
| | PHB2 | Prohibitin. (299 aa) |
| | STX12 | Syntaxin 12; Belongs to the syntaxin family. (276 aa) |
| | TMEM74 | Transmembrane protein 74. (305 aa) |
| | LIX1 | Limb and CNS expressed 1. (227 aa) |
| | EMC6 | ER membrane protein complex subunit 6. (110 aa) |
| | NPC1 | NPC intracellular cholesterol transporter 1. (1277 aa) |
| | ENSMNEP00000000212 | Uncharacterized protein. (175 aa) |
| | ENSMNEP00000000089 | Uncharacterized protein. (197 aa) |
| | MFN2 | Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa) |
| | ENSMNEP00000045802 | Uncharacterized protein. (119 aa) |
| | VMP1 | Vacuole membrane protein 1. (406 aa) |
| | STAM2 | Signal transducing adaptor molecule 2. (525 aa) |
| | CHMP2B | Charged multivesicular body protein 2B. (218 aa) |
| | RAB33B | RAB33B, member RAS oncogene family. (229 aa) |
| | MCOLN1 | Mucolipin 1. (580 aa) |
| | SNAPIN | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa) |
| | SRC | Tyrosine-protein kinase. (644 aa) |
| | PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa) |
| | TIGAR | TP53 induced glycolysis regulatory phosphatase. (270 aa) |
| | ENSMNEP00000007677 | Uncharacterized protein. (200 aa) |
| | ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (704 aa) |
| | ENSMNEP00000008139 | Uncharacterized protein. (111 aa) |
| | EPM2A | EPM2A glucan phosphatase, laforin. (331 aa) |
| | MFSD8 | Major facilitator superfamily domain containing 8. (518 aa) |
| | ATG13 | Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa) |
| | TP53INP1 | Tumor protein p53 inducible nuclear protein 1. (241 aa) |
| | RAB43 | RAB43, member RAS oncogene family. (212 aa) |
| | STAM | Signal transducing adaptor molecule. (540 aa) |
| | PIP4K2B | Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (398 aa) |
| | STX17 | Syntaxin 17; Belongs to the syntaxin family. (302 aa) |
| | VPS28 | Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (223 aa) |
| | ATP13A2 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1184 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2546 aa) |
| | MTMR3 | Myotubularin related protein 3. (1207 aa) |
| | ARL8B | ADP ribosylation factor like GTPase 8B; Belongs to the small GTPase superfamily. Arf family. (186 aa) |
| | DDRGK1 | DDRGK domain containing 1. (342 aa) |
| | ATG16L1 | Autophagy related 16 like 1. (624 aa) |
| | ATG9A | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (851 aa) |
| | RNF213 | Ring finger protein 213. (5123 aa) |
| | SYNPO2 | Synaptopodin 2. (1261 aa) |
| | ENSMNEP00000012226 | Uncharacterized protein. (104 aa) |
| | UBXN6 | UBX domain protein 6. (465 aa) |
| | SMURF1 | SMAD specific E3 ubiquitin protein ligase 1. (641 aa) |
| | ULK2 | Unc-51 like autophagy activating kinase 2. (1035 aa) |
| | TEX264 | Testis expressed 264, ER-phagy receptor. (313 aa) |
| | HMOX1 | Heme oxygenase 1. (288 aa) |
| | BECN1 | Beclin 1. (450 aa) |
| | LOC105476784 | Uncharacterized protein. (147 aa) |
| | UBA5 | Ubiquitin like modifier activating enzyme 5. (404 aa) |
| | ATG14 | Autophagy related 14. (493 aa) |
| | VTI1A | Vesicle transport through interaction with t-SNAREs 1A. (217 aa) |
| | RB1CC1 | RB1 inducible coiled-coil 1. (1594 aa) |
| | ATP2A2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | PGAM5 | Uncharacterized protein. (140 aa) |
| | ENSMNEP00000016623 | Uncharacterized protein. (111 aa) |
| | SNF8 | Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1044 aa) |
| | PINK1 | PTEN induced kinase 1. (581 aa) |
| | CHMP4B | Charged multivesicular body protein 4B. (210 aa) |
| | SNX30 | Sorting nexin family member 30. (437 aa) |
| | KIAA1324 | KIAA1324. (993 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) |
| | RETREG3 | Reticulophagy regulator family member 3. (466 aa) |
| | ENSMNEP00000018005 | Uncharacterized protein. (133 aa) |
| | ENSMNEP00000018092 | Prohibitin. (270 aa) |
| | VPS41 | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa) |
| | ATG12 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa) |
| | PLEKHM1 | Pleckstrin homology and RUN domain containing M1. (1055 aa) |
| | RAB7A | RAB7A, member RAS oncogene family. (207 aa) |
| | MAP1LC3A | Microtubule associated protein 1 light chain 3 alpha. (125 aa) |
| | VPS37A | VPS37A subunit of ESCRT-I. (397 aa) |
| | HDAC10 | Histone deacetylase 10. (672 aa) |
| | VPS39 | VPS39 subunit of HOPS complex. (886 aa) |
| | LOC105494194 | Uncharacterized protein. (222 aa) |
| | LOC105465405 | Charged multivesicular body protein 3. (222 aa) |
| | ENSMNEP00000020540 | Uncharacterized protein. (299 aa) |
| | TMEM41B | Transmembrane protein 41B. (292 aa) |
| | ULK1 | Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1049 aa) |
| | CHMP1A | Charged multivesicular body protein 1A. (196 aa) |
| | ENSMNEP00000021271 | Prohibitin. (286 aa) |
| | LAMP2 | Lysosomal associated membrane protein 2. (411 aa) |
| | SNAP29 | Synaptosome associated protein 29. (258 aa) |
| | PRAF2 | Uncharacterized protein. (361 aa) |
| | AUP1 | AUP1 lipid droplet regulating VLDL assembly factor. (410 aa) |
| | LIX1L | Limb and CNS expressed 1 like. (305 aa) |
| | CHMP2A | Charged multivesicular body protein 2A. (222 aa) |
| | ILRUN | Inflammation and lipid regulator with UBA-like and NBR1-like domains. (298 aa) |
| | LGALS8 | Galectin. (358 aa) |
| | VPS4A | Uncharacterized protein; Belongs to the AAA ATPase family. (498 aa) |
| | MAP1LC3B | Uncharacterized protein. (125 aa) |
| | ENSMNEP00000022820 | Uncharacterized protein. (148 aa) |
| | WIPI2 | WD repeat domain, phosphoinositide interacting 2. (451 aa) |
| | IRGM | Immunity related GTPase M. (170 aa) |
| | SPATA33 | Spermatogenesis associated 33. (140 aa) |
| | CHMP4C | Charged multivesicular body protein 4C. (233 aa) |
| | CHMP7 | Charged multivesicular body protein 7. (453 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (891 aa) |
| | PJVK | Pejvakin. (352 aa) |
| | VPS25 | Vacuolar protein sorting 25 homolog. (176 aa) |
| | RUFY4 | RUN and FYVE domain containing 4. (571 aa) |
| | ATG16L2 | Autophagy related 16 like 2. (696 aa) |
| | ENSMNEP00000025146 | Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (572 aa) |
| | UVRAG | UV radiation resistance associated. (699 aa) |
| | MTMR14 | Myotubularin related protein 14. (650 aa) |
| | ENSMNEP00000025490 | V-SNARE domain-containing protein. (198 aa) |
| | VAMP8 | Vesicle associated membrane protein 8. (100 aa) |
| | VCP | Valosin containing protein. (767 aa) |
| | WDR81 | WD repeat domain 81. (1928 aa) |
| | VPS37B | VPS37B subunit of ESCRT-I. (285 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) |
| | CHMP5 | Charged multivesicular body protein 5. (219 aa) |
| | CLN3 | Battenin. (438 aa) |
| | RAB23 | RAB23, member RAS oncogene family. (237 aa) |
| | HGS | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (830 aa) |
| | ATG9B | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (922 aa) |
| | WDFY3 | WD repeat and FYVE domain containing 3. (3526 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa) |
| | CHMP6 | Charged multivesicular body protein 6. (223 aa) |
| | PIP4K2A | Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (406 aa) |
| | PIK3R4 | Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa) |
| | VPS16 | Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (839 aa) |
| | UBQLN2 | Ubiquilin 2. (624 aa) |
| | ENSMNEP00000028818 | Uncharacterized protein. (212 aa) |
| | SPG11 | SPG11 vesicle trafficking associated, spatacsin. (2329 aa) |
| | TRAPPC8 | Trafficking protein particle complex 8. (925 aa) |
| | ATG4B | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (508 aa) |
| | NSFL1C | NSFL1 cofactor. (372 aa) |
| | ATG101 | Autophagy related 101. (218 aa) |
| | TAZ | Tafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (292 aa) |
| | EI24 | EI24 autophagy associated transmembrane protein. (340 aa) |
| | ULK3 | Unc-51 like kinase 3; Belongs to the protein kinase superfamily. (472 aa) |
| | UBXN2A | UBX domain protein 2A. (260 aa) |
| | PACS2 | Phosphofurin acidic cluster sorting protein 2. (900 aa) |
| | STING1 | Transmembrane protein 173. (379 aa) |
| | ZFYVE26 | Zinc finger FYVE-type containing 26. (2522 aa) |
| | TBC1D5 | TBC1 domain family member 5. (821 aa) |
| | TECPR1 | Tectonin beta-propeller repeat containing 1. (1213 aa) |
| | ATG2A | Autophagy related 2A. (1968 aa) |
| | ARL8A | ADP ribosylation factor like GTPase 8A; Belongs to the small GTPase superfamily. Arf family. (186 aa) |
| | ENSMNEP00000033415 | Uncharacterized protein. (145 aa) |
| | WDR45B | WD repeat domain 45B. (298 aa) |
| | VPS36 | Vacuolar protein sorting 36 homolog. (380 aa) |
| | GABARAPL1 | GABA type A receptor associated protein like 1. (146 aa) |
| | PLAA | Phospholipase A2 activating protein. (795 aa) |
| | ENSMNEP00000035659 | Prohibitin. (112 aa) |
| | OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa) |
| | AMBRA1 | Autophagy and beclin 1 regulator 1. (1298 aa) |
| | MVB12A | Multivesicular body subunit 12A. (273 aa) |
| | CALCOCO2 | Calcium binding and coiled-coil domain 2. (465 aa) |
| | UBXN2B | UBX domain protein 2B. (331 aa) |
| | UFM1 | Ubiquitin fold modifier 1. (103 aa) |
| | RETREG1 | Reticulophagy regulator 1. (497 aa) |
| | TSG101 | Tumor susceptibility 101. (390 aa) |
| | ATG10 | Autophagy related 10. (228 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa) |
| | ENSMNEP00000038197 | Uncharacterized protein. (121 aa) |
| | WIPI1 | WD repeat domain, phosphoinositide interacting 1. (462 aa) |
| | ENSMNEP00000038473 | Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (214 aa) |
| | BAG3 | BCL2 associated athanogene 3. (575 aa) |
| | NBR1 | NBR1 autophagy cargo receptor. (960 aa) |
| | ARFIP2 | ADP ribosylation factor interacting protein 2. (341 aa) |
| | RETREG2 | Reticulophagy regulator family member 2. (622 aa) |
| | STBD1 | Starch binding domain 1. (358 aa) |
| | ATG3 | Autophagy-related protein 3. (314 aa) |
| | ENSMNEP00000040770 | Uncharacterized protein. (156 aa) |
| | RUBCNL | Rubicon like autophagy enhancer. (677 aa) |
| | EPG5 | Ectopic P-granules autophagy protein 5 homolog. (2560 aa) |
| | UFC1 | Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage. (167 aa) |
| | USP30 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (517 aa) |
| | RAB19 | RAB19, member RAS oncogene family. (217 aa) |
| | ATG4D | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (447 aa) |
