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TEP1 TEP1 FLAD1 FLAD1 TUT7 TUT7 HAUS3 HAUS3 ENSMNEP00000013394 ENSMNEP00000013394 CDS2 CDS2 OAS2 OAS2 TENT5B TENT5B CHRAC1 CHRAC1 KARS1 KARS1 ARID3A ARID3A POLR1A POLR1A DNTT DNTT PAPOLA PAPOLA POLN POLN POLR2F POLR2F POLR3B POLR3B OAS1 OAS1 OAS3 OAS3 CMAS CMAS CGAS CGAS ENSMNEP00000045412 ENSMNEP00000045412 MB21D2 MB21D2 MAB21L2 MAB21L2 GMPPA GMPPA LOC105490206 LOC105490206 TUT4 TUT4 MOCS3 MOCS3 ENSMNEP00000002797 ENSMNEP00000002797 MAB21L1 MAB21L1 POLD4 POLD4 POLE4 POLE4 POLK POLK TENT5C TENT5C ENSMNEP00000003956 ENSMNEP00000003956 ENSMNEP00000004026 ENSMNEP00000004026 PCYT2 PCYT2 POLG POLG POLB POLB POLR3H POLR3H POLE2 POLE2 POLR2K POLR2K GDPGP1 GDPGP1 POLR2L POLR2L PAPSS1 PAPSS1 POLR1C POLR1C ABL1 ABL1 FPGT FPGT PCYT1B PCYT1B RPAP1 RPAP1 ENSMNEP00000008468 ENSMNEP00000008468 TENT4A TENT4A TENT5A TENT5A ENSMNEP00000009730 ENSMNEP00000009730 YRDC YRDC POLR2I POLR2I ENSMNEP00000010162 ENSMNEP00000010162 OASL OASL POLR3G POLR3G TUT1 TUT1 COASY COASY NMNAT2 NMNAT2 POLR2K-2 POLR2K-2 NUDT5 NUDT5 ENSMNEP00000038883 ENSMNEP00000038883 POLH POLH POLR2B POLR2B POLI POLI POLG2 POLG2 TERT TERT TWISTNB TWISTNB POLR3C POLR3C CTU2 CTU2 PCYT1A PCYT1A RNGTT RNGTT FHIT FHIT GMPPB GMPPB TAMM41 TAMM41 POLR2A POLR2A UAP1 UAP1 CTU1 CTU1 ENSMNEP00000032820 ENSMNEP00000032820 MTPAP MTPAP MED21 MED21 EIF2B3 EIF2B3 TENT2 TENT2 POLD1 POLD1 POLRMT POLRMT NANS NANS UGP2 UGP2 PNPT1 PNPT1 THG1L THG1L ENSMNEP00000029296 ENSMNEP00000029296 TRNT1 TRNT1 UAP1L1 UAP1L1 CRPPA CRPPA PAPSS2 PAPSS2 CLMP CLMP TENT4B TENT4B POLR1B POLR1B PAPOLG PAPOLG ENSMNEP00000024580 ENSMNEP00000024580 ENSMNEP00000024561 ENSMNEP00000024561 SELENOO SELENOO POLE POLE POLR3A POLR3A NMNAT1 NMNAT1 POLQ POLQ GPHN GPHN REV3L REV3L DKC1 DKC1 NMNAT3 NMNAT3 POLR2E POLR2E FICD FICD POLR2C POLR2C ENSMNEP00000019366 ENSMNEP00000019366 ENSMNEP00000019120 ENSMNEP00000019120 REV1 REV1 POLR3F POLR3F CDS1 CDS1 PRIMPOL PRIMPOL PRIM1 PRIM1 POLM POLM POLL POLL POLA1 POLA1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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TEP1Telomerase associated protein 1. (2622 aa)
FLAD1FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. (562 aa)
TUT7Terminal uridylyl transferase 7. (1536 aa)
HAUS3HAUS augmin like complex subunit 3. (603 aa)
ENSMNEP00000013394RPOL4c domain-containing protein. (98 aa)
CDS2Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (445 aa)
OAS22'-5'-oligoadenylate synthetase 2. (687 aa)
TENT5BTerminal nucleotidyltransferase 5B. (425 aa)
CHRAC1Chromatin accessibility complex subunit 1. (131 aa)
KARS1Lysine--tRNA ligase. (618 aa)
ARID3AAT-rich interaction domain 3A. (589 aa)
POLR1ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1720 aa)
DNTTDNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (510 aa)
PAPOLAPoly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (745 aa)
POLNDNA polymerase nu. (881 aa)
POLR2FRNA polymerase II subunit F. (158 aa)
POLR3BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1148 aa)
OAS12'-5'-oligoadenylate synthetase 1. (488 aa)
OAS32'-5'-oligoadenylate synthetase 3. (1076 aa)
CMASCytidine monophosphate N-acetylneuraminic acid synthetase. (434 aa)
CGASCyclic GMP-AMP synthase. (522 aa)
ENSMNEP00000045412Uncharacterized protein. (188 aa)
MB21D2Mab-21 domain containing 2. (491 aa)
MAB21L2Mab-21 like 2. (359 aa)
GMPPAGDP-mannose pyrophosphorylase A. (425 aa)
LOC105490206RNA_pol_L_2 domain-containing protein. (133 aa)
TUT4Terminal uridylyl transferase 4. (1581 aa)
MOCS3Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (460 aa)
ENSMNEP00000002797S1 motif domain-containing protein. (248 aa)
MAB21L1Mab-21 like 1. (359 aa)
POLD4Uncharacterized protein. (107 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (117 aa)
POLKDNA polymerase kappa. (870 aa)
TENT5CTerminal nucleotidyltransferase 5C. (391 aa)
ENSMNEP00000003956RPOL9 domain-containing protein. (101 aa)
ENSMNEP00000004026Uncharacterized protein. (126 aa)
PCYT2Phosphate cytidylyltransferase 2, ethanolamine. (402 aa)
POLGDNA polymerase gamma, catalytic subunit. (1228 aa)
POLBDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa)
POLR3HRNA polymerase III subunit H. (204 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
POLR2KUncharacterized protein. (58 aa)
GDPGP1Uncharacterized protein. (385 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
PAPSS13'-phosphoadenosine 5'-phosphosulfate synthase 1. (624 aa)
POLR1CRNA polymerase I and III subunit C. (350 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
FPGTFucose-1-phosphate guanylyltransferase. (607 aa)
PCYT1BPhosphate cytidylyltransferase 1, choline, beta. (369 aa)
RPAP1RNA polymerase II associated protein 1. (1393 aa)
ENSMNEP00000008468Uncharacterized protein. (235 aa)
TENT4ATerminal nucleotidyltransferase 4A. (788 aa)
TENT5ATerminal nucleotidyltransferase 5A. (465 aa)
ENSMNEP00000009730Uncharacterized protein. (265 aa)
YRDCYrdC N6-threonylcarbamoyltransferase domain containing. (371 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
ENSMNEP00000010162Uncharacterized protein. (63 aa)
OASL2'-5'-oligoadenylate synthetase like. (515 aa)
POLR3GDNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (223 aa)
TUT1RRM domain-containing protein. (908 aa)
COASYCoenzyme A synthase. (564 aa)
NMNAT2Nicotinamide nucleotide adenylyltransferase 2. (307 aa)
POLR2K-2Uncharacterized protein. (67 aa)
NUDT5Nudix hydrolase 5; Belongs to the Nudix hydrolase family. (232 aa)
ENSMNEP00000038883ATP_bind_3 domain-containing protein. (284 aa)
POLHDNA polymerase eta. (711 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
POLIDNA polymerase iota. (659 aa)
POLG2DNA polymerase gamma 2, accessory subunit. (485 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1132 aa)
TWISTNBTWIST neighbor. (338 aa)
POLR3CRNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (534 aa)
CTU2Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Belongs to the CTU2/NCS2 family. (568 aa)
PCYT1APhosphate cytidylyltransferase 1, choline, alpha. (380 aa)
RNGTTPolynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (597 aa)
FHITBis(5'-adenosyl)-triphosphatase. (149 aa)
GMPPBGDP-mannose pyrophosphorylase B. (387 aa)
TAMM41Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane. (442 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1977 aa)
UAP1UDP-N-acetylglucosamine pyrophosphorylase 1. (522 aa)
CTU1Cytosolic thiouridylase subunit 1. (321 aa)
ENSMNEP00000032820Uncharacterized protein. (483 aa)
MTPAPMitochondrial poly(A) polymerase. (582 aa)
MED21Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (160 aa)
EIF2B3Eukaryotic translation initiation factor 2B subunit gamma. (452 aa)
TENT2Terminal nucleotidyltransferase 2. (484 aa)
POLD1DNA polymerase. (1126 aa)
POLRMTDNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1251 aa)
NANSN-acetylneuraminate synthase. (359 aa)
UGP2UTP--glucose-1-phosphate uridylyltransferase. (517 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (754 aa)
THG1LtRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (298 aa)
ENSMNEP00000029296RNA_pol_L_2 domain-containing protein. (125 aa)
TRNT1tRNA nucleotidyl transferase 1; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (439 aa)
UAP1L1UDP-N-acetylglucosamine pyrophosphorylase 1 like 1. (508 aa)
CRPPACDP-L-ribitol pyrophosphorylase A. (451 aa)
PAPSS23'-phosphoadenosine 5'-phosphosulfate synthase 2. (619 aa)
CLMPCXADR like membrane protein. (376 aa)
TENT4BTerminal nucleotidyltransferase 4B. (701 aa)
POLR1BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1158 aa)
PAPOLGPoly(A) polymerase gamma. (707 aa)
ENSMNEP00000024580RNA_pol_L_2 domain-containing protein. (279 aa)
ENSMNEP00000024561Lysine--tRNA ligase. (520 aa)
SELENOOSelenoprotein O. (666 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2263 aa)
POLR3ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1353 aa)
NMNAT1Nicotinamide-nucleotide adenylyltransferase. (279 aa)
POLQDNA polymerase theta. (2720 aa)
GPHNMolybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (782 aa)
REV3LREV3 like, DNA directed polymerase zeta catalytic subunit. (3124 aa)
DKC1Dyskerin pseudouridine synthase 1. (514 aa)
NMNAT3Nicotinamide-nucleotide adenylyltransferase. (252 aa)
POLR2ERNA polymerase II subunit E. (211 aa)
FICDFIC domain containing. (460 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
ENSMNEP00000019366Uncharacterized protein. (69 aa)
ENSMNEP00000019120RNA_pol_Rpb5_N domain-containing protein. (175 aa)
REV1DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1250 aa)
POLR3FDNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (316 aa)
CDS1Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (461 aa)
PRIMPOLPrimase and DNA directed polymerase. (556 aa)
PRIM1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (374 aa)
POLMDNA polymerase mu. (495 aa)
POLLDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (575 aa)
POLA1DNA polymerase. (1478 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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