29 items (Macaca nemestrina) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

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Your Input:
	FGF13	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
	SCN2B	Sodium voltage-gated channel beta subunit 2. (215 aa)
	SNTA1	Syntrophin alpha 1. (554 aa)
	YWHAH	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa)
	SCLT1	Sodium channel and clathrin linker 1. (717 aa)
	FXYD2	FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
	PRSS41	Serine protease 41; Belongs to the peptidase S1 family. (318 aa)
	SCN1B	Sodium voltage-gated channel beta subunit 1. (243 aa)
	SCN4B	Sodium voltage-gated channel beta subunit 4. (270 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	CAMK2D	Calcium/calmodulin dependent protein kinase II delta. (533 aa)
	PRSS8	Serine protease 8; Belongs to the peptidase S1 family. (362 aa)
	COMMD1	Copper metabolism domain containing 1. (184 aa)
	FGF11	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa)
	ATP2B4	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
	FGF14	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (247 aa)
	PKP2	Plakophilin 2. (869 aa)
	PTPN3	Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (913 aa)
	SCN3B	Sodium voltage-gated channel beta subunit 3. (215 aa)
	FXYD1	FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (92 aa)
	NEDD4	NEDD4 E3 ubiquitin protein ligase. (1316 aa)
	TMPRSS3	Transmembrane serine protease 3; Belongs to the peptidase S1 family. (454 aa)
	RANGRF	RAN guanine nucleotide release factor. (186 aa)
	SGK2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (367 aa)
	GPLD1	Glycosylphosphatidylinositol specific phospholipase D1. (847 aa)
	FGF12	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
	NOS1	Nitric oxide synthase 1. (1468 aa)
	PCSK9	Proprotein convertase subtilisin/kexin type 9; Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway. May prevent the recycling of LDLR from endosomes to [...] (811 aa)
	ENSMNEP00000026290	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP2B4	FXYD2	ENSMNEP00000007898	ENSMNEP00000035472	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.472
ATP2B4	NOS1	ENSMNEP00000007898	ENSMNEP00000024708	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Nitric oxide synthase 1.	0.870
ATP2B4	SNTA1	ENSMNEP00000007898	ENSMNEP00000029870	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Syntrophin alpha 1.	0.401
CAMK2D	NOS1	ENSMNEP00000046054	ENSMNEP00000024708	Calcium/calmodulin dependent protein kinase II delta.	Nitric oxide synthase 1.	0.867
CAV3	NOS1	ENSMNEP00000045133	ENSMNEP00000024708	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Nitric oxide synthase 1.	0.670
CAV3	SCN4B	ENSMNEP00000045133	ENSMNEP00000043078	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Sodium voltage-gated channel beta subunit 4.	0.438
CAV3	SNTA1	ENSMNEP00000045133	ENSMNEP00000029870	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Syntrophin alpha 1.	0.553
FXYD1	FXYD2	ENSMNEP00000018062	ENSMNEP00000035472	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.928
FXYD2	ATP2B4	ENSMNEP00000035472	ENSMNEP00000007898	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.472
FXYD2	FXYD1	ENSMNEP00000035472	ENSMNEP00000018062	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.928
NEDD4	SGK2	ENSMNEP00000018158	ENSMNEP00000024020	NEDD4 E3 ubiquitin protein ligase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.674
NEDD4	YWHAH	ENSMNEP00000018158	ENSMNEP00000032901	NEDD4 E3 ubiquitin protein ligase.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family.	0.611
NOS1	ATP2B4	ENSMNEP00000024708	ENSMNEP00000007898	Nitric oxide synthase 1.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.870
NOS1	CAMK2D	ENSMNEP00000024708	ENSMNEP00000046054	Nitric oxide synthase 1.	Calcium/calmodulin dependent protein kinase II delta.	0.867
NOS1	CAV3	ENSMNEP00000024708	ENSMNEP00000045133	Nitric oxide synthase 1.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.670
NOS1	SNTA1	ENSMNEP00000024708	ENSMNEP00000029870	Nitric oxide synthase 1.	Syntrophin alpha 1.	0.907
RANGRF	SCN1B	ENSMNEP00000022143	ENSMNEP00000039574	RAN guanine nucleotide release factor.	Sodium voltage-gated channel beta subunit 1.	0.418
RANGRF	SCN2B	ENSMNEP00000022143	ENSMNEP00000026947	RAN guanine nucleotide release factor.	Sodium voltage-gated channel beta subunit 2.	0.493
RANGRF	SCN3B	ENSMNEP00000022143	ENSMNEP00000017128	RAN guanine nucleotide release factor.	Sodium voltage-gated channel beta subunit 3.	0.469
SCN1B	RANGRF	ENSMNEP00000039574	ENSMNEP00000022143	Sodium voltage-gated channel beta subunit 1.	RAN guanine nucleotide release factor.	0.418