STRINGSTRING
CDK10 CDK10 VRK1 VRK1 CDK5R1 CDK5R1 PRKCB PRKCB GSK3B GSK3B CSNK2A1 CSNK2A1 DYRK1A DYRK1A CSNK2A2 CSNK2A2 MTOR MTOR STK11 STK11 MAP3K10 MAP3K10 LRRK2 LRRK2 MAPK1 MAPK1 HIPK3 HIPK3 WNK1 WNK1 MAPK8 MAPK8 TSSK4 TSSK4 LOC105463814 LOC105463814 CAD CAD CLK1 CLK1 UMOD UMOD TGFBR2 TGFBR2 PRKDC PRKDC HIPK1 HIPK1 TAF1 TAF1 HIPK2 HIPK2 PRKCD PRKCD NLK NLK SBK1 SBK1 PRKD2 PRKD2 GSK3A GSK3A MAP3K12 MAP3K12 LMTK2 LMTK2 CDC42BPB CDC42BPB ATF2 ATF2 ROCK1 ROCK1 PRKCA PRKCA OXSR1 OXSR1 ACVR1 ACVR1 AKT1 AKT1 BCL2 BCL2 TTBK1 TTBK1 CDC42BPA CDC42BPA ULK1 ULK1 MYLK2 MYLK2 DYRK4 DYRK4 TGFBR1 TGFBR1 CAMK2A CAMK2A CDK5 CDK5 ENSMNEP00000044158 ENSMNEP00000044158 CHEK1 CHEK1 PDPK1 PDPK1 MARK2 MARK2 CAMK2D CAMK2D CDK1 CDK1 ROCK2 ROCK2 DYRK1B DYRK1B TBK1 TBK1 MAPK10 MAPK10 DCAF1 DCAF1 ACVR1B ACVR1B TNKS TNKS WNK3 WNK3 GRK2 GRK2 STK39 STK39 PRKD1 PRKD1 DYRK2 DYRK2 CIT CIT PKN1 PKN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDK10Cyclin dependent kinase 10; Belongs to the protein kinase superfamily. (361 aa)
VRK1VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily. (396 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (763 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (345 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2546 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase. (952 aa)
LRRK2Leucine rich repeat kinase 2. (2512 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
HIPK3Homeodomain interacting protein kinase 3. (1215 aa)
WNK1OSR1_C domain-containing protein. (2398 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
TSSK4Testis specific serine kinase 4. (338 aa)
LOC105463814Protein kinase domain-containing protein. (393 aa)
CADCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2242 aa)
CLK1CDC like kinase 1. (596 aa)
UMODUromodulin. (641 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4054 aa)
HIPK1Homeodomain interacting protein kinase 1. (1210 aa)
TAF1Transcription initiation factor TFIID subunit. (1875 aa)
HIPK2Homeodomain interacting protein kinase 2. (1198 aa)
PRKCDProtein kinase C. (729 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
SBK1Serine/threonine-protein kinase SBK1; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (424 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (890 aa)
LMTK2Lemur tyrosine kinase 2. (1502 aa)
CDC42BPBCDC42 binding protein kinase beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1728 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
OXSR1Oxidative stress responsive kinase 1. (527 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
TTBK1Tau tubulin kinase 1. (1324 aa)
CDC42BPANon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1732 aa)
ULK1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1049 aa)
MYLK2Myosin light chain kinase 2. (595 aa)
DYRK4Dual specificity tyrosine phosphorylation regulated kinase 4. (634 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
ENSMNEP00000044158Protein kinase domain-containing protein. (279 aa)
CHEK1Checkpoint kinase 1. (493 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (582 aa)
MARK2Non-specific serine/threonine protein kinase. (788 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1474 aa)
DYRK1BDual specificity tyrosine phosphorylation regulated kinase 1B. (629 aa)
TBK1TANK binding kinase 1. (729 aa)
MAPK10Mitogen-activated protein kinase. (489 aa)
DCAF1DDB1 and CUL4 associated factor 1. (1478 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
WNK3WNK lysine deficient protein kinase 3. (1741 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa)
STK39Serine/threonine kinase 39. (550 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (892 aa)
DYRK2Dual specificity tyrosine phosphorylation regulated kinase 2. (601 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2069 aa)
PKN1Protein kinase N1. (949 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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