STRINGSTRING
POLN POLN ENSMNEP00000045253 ENSMNEP00000045253 DTL DTL USP10 USP10 POLE2 POLE2 ENSMNEP00000004116 ENSMNEP00000004116 POLK POLK POLDIP2 POLDIP2 PARP10 PARP10 REV3L REV3L MAD2L2 MAD2L2 REV1 REV1 USP1 USP1 POLD2 POLD2 PRIMPOL PRIMPOL ZBTB1 ZBTB1 PCNA PCNA PCLAF PCLAF SPRTN SPRTN VCP VCP POLD1 POLD1 RCHY1 RCHY1 USP43 USP43 POLI POLI POLH POLH POLD3 POLD3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLNDNA polymerase nu. (881 aa)
ENSMNEP00000045253Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (234 aa)
DTLDenticleless E3 ubiquitin protein ligase homolog. (730 aa)
USP10Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (802 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
ENSMNEP00000004116USP domain-containing protein. (289 aa)
POLKDNA polymerase kappa. (870 aa)
POLDIP2DNA polymerase delta interacting protein 2. (408 aa)
PARP10Poly [ADP-ribose] polymerase. (1026 aa)
REV3LREV3 like, DNA directed polymerase zeta catalytic subunit. (3124 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (211 aa)
REV1DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1250 aa)
USP1Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (785 aa)
POLD2DNA polymerase delta 2, accessory subunit. (504 aa)
PRIMPOLPrimase and DNA directed polymerase. (556 aa)
ZBTB1Zinc finger and BTB domain containing 1. (644 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
PCLAFPAF domain-containing protein. (115 aa)
SPRTNSprT-like N-terminal domain. (488 aa)
VCPValosin containing protein. (767 aa)
POLD1DNA polymerase. (1126 aa)
RCHY1Ring finger and CHY zinc finger domain containing 1. (261 aa)
USP43Ubiquitin specific peptidase 43; Belongs to the peptidase C19 family. (1012 aa)
POLIDNA polymerase iota. (659 aa)
POLHDNA polymerase eta. (711 aa)
POLD3Uncharacterized protein. (466 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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