STRINGSTRING
SLIT2 SLIT2 IFRD2 IFRD2 LOC105480945 LOC105480945 CAV3 CAV3 TNR TNR IFRD1 IFRD1 ENSMNEP00000044158 ENSMNEP00000044158 GNG4 GNG4 DCC DCC ENSMNEP00000043817 ENSMNEP00000043817 SEMA3E SEMA3E TRIM46 TRIM46 CDK5 CDK5 DIP2B DIP2B PTPRJ PTPRJ WFDC1 WFDC1 WNT3 WNT3 MAG MAG SEMA5A SEMA5A ST20 ST20 HNF4A HNF4A NDRG3 NDRG3 IP6K2 IP6K2 PPP2CA PPP2CA SEMA3D SEMA3D TGFB2 TGFB2 SPP1 SPP1 MUL1 MUL1 SEMA3G SEMA3G PML PML TGFB1 TGFB1 SPART SPART PPARD PPARD SEMA4F SEMA4F RERG RERG WNT11 WNT11 BMP10 BMP10 SMARCA2 SMARCA2 SCGB3A1 SCGB3A1 ENSMNEP00000037716 ENSMNEP00000037716 INHBA INHBA ACVR1B ACVR1B DRAXIN DRAXIN DCSTAMP DCSTAMP SEMA4C SEMA4C MYL2 MYL2 SEMA5B SEMA5B ENSMNEP00000036627 ENSMNEP00000036627 ST7L ST7L RTN4R RTN4R SEMA3A SEMA3A CGRRF1 CGRRF1 FHL1 FHL1 BCL11A BCL11A MT3 MT3 SESN2 SESN2 SPHK2 SPHK2 ING1 ING1 FSTL4 FSTL4 ARHGAP4 ARHGAP4 SH3BP4 SH3BP4 NDUFA13 NDUFA13 NPPB NPPB ENSMNEP00000032223 ENSMNEP00000032223 VGLL4 VGLL4 BTG1 BTG1 EI24 EI24 GDF2 GDF2 SFRP2 SFRP2 DNAJB2 DNAJB2 MAP2 MAP2 GSK3A GSK3A ACVRL1 ACVRL1 NRP1 NRP1 JADE1 JADE1 CDHR2 CDHR2 NPR1 NPR1 SEMA3F SEMA3F HRG HRG WNT3A WNT3A OSGIN1 OSGIN1 SFRP1 SFRP1 C10orf90 C10orf90 HYAL1 HYAL1 DCUN1D3 DCUN1D3 GDF9 GDF9 ENSMNEP00000026290 ENSMNEP00000026290 FGF13 FGF13 ENSMNEP00000026182 ENSMNEP00000026182 BST2 BST2 PPT1 PPT1 EAF2 EAF2 SPAG9 SPAG9 SLIT3 SLIT3 FRZB FRZB HYAL2 HYAL2 SEMA6C SEMA6C TSPYL2 TSPYL2 BCL2 BCL2 TP53TG5 TP53TG5 DCBLD2 DCBLD2 SEMA6B SEMA6B PTPRS PTPRS EPHA7 EPHA7 CDA CDA SIRT1 SIRT1 PPARA PPARA SOX17 SOX17 ENSMNEP00000021373 ENSMNEP00000021373 ADAM15 ADAM15 PPP2R1A PPP2R1A ULK1 ULK1 BCL6 BCL6 SEMA4D SEMA4D RGS2 RGS2 CDKN2D CDKN2D PPP1R9B PPP1R9B RACK1 RACK1 SMAD3 SMAD3 SEMA6A SEMA6A MSX1 MSX1 ENSMNEP00000017328 ENSMNEP00000017328 SIPA1 SIPA1 OSGIN2 OSGIN2 BMPR2 BMPR2 ENSMNEP00000016907 ENSMNEP00000016907 RYK RYK CDKN2AIP CDKN2AIP CYP27B1 CYP27B1 DDX3X DDX3X CDKN2C CDKN2C CDKN1B CDKN1B BDKRB1 BDKRB1 ENSMNEP00000014571 ENSMNEP00000014571 SMARCA4 SMARCA4 G6PD G6PD RBBP7 RBBP7 CCAR2 CCAR2 SMAD4 SMAD4 ULK2 ULK2 SLIT1 SLIT1 ENSMNEP00000012842 ENSMNEP00000012842 OSTN OSTN ENSMNEP00000012285 ENSMNEP00000012285 RB1 RB1 NDUFS3 NDUFS3 ENSMNEP00000011594 ENSMNEP00000011594 PHB PHB CAPRIN2 CAPRIN2 TCHP TCHP PLXNA3 PLXNA3 RTN4 RTN4 STK11 STK11 CTDP1 CTDP1 SEMA4G SEMA4G DAB2 DAB2 SEMA3B SEMA3B SEMA4B SEMA4B PSRC1 PSRC1 FOXP1 FOXP1 NTN1 NTN1 PRDM11 PRDM11 FBP1 FBP1 MINAR1 MINAR1 ENSMNEP00000006880 ENSMNEP00000006880 ENPP1 ENPP1 SEMA4A SEMA4A AGTR2 AGTR2 PI16 PI16 CCN3 CCN3 MYL10 MYL10 ENSMNEP00000005266 ENSMNEP00000005266 WNT5A WNT5A TOMM70 TOMM70 FLCN FLCN SERPINE2 SERPINE2 SEMA7A SEMA7A SERTAD3 SERTAD3 SERTAD1 SERTAD1 ENSMNEP00000002536 ENSMNEP00000002536 WT1 WT1 CDKN1A CDKN1A KIAA0319 KIAA0319 SERTAD2 SERTAD2 DACT3 DACT3 ZC3H12D ZC3H12D CCDC85B CCDC85B GAS2L1 GAS2L1 RNF6 RNF6 NME6 NME6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLIT2Slit guidance ligand 2. (1542 aa)
IFRD2Uncharacterized protein. (510 aa)
LOC105480945RING-type domain-containing protein. (321 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
TNRTenascin R. (1358 aa)
IFRD1Interferon related developmental regulator 1. (451 aa)
ENSMNEP00000044158Protein kinase domain-containing protein. (279 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
DCCDCC netrin 1 receptor. (1352 aa)
ENSMNEP00000043817Prohibitin. (263 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (775 aa)
TRIM46Tripartite motif containing 46. (759 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
DIP2BDisco interacting protein 2 homolog B. (1576 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1340 aa)
WFDC1WAP four-disulfide core domain 1. (220 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
MAGMyelin associated glycoprotein. (772 aa)
SEMA5ASemaphorin 5A. (1074 aa)
ST20Uncharacterized protein. (78 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (474 aa)
NDRG3NDRG family member 3. (359 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (475 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (777 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
SPP1Secreted phosphoprotein 1. (314 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (782 aa)
PMLPromyelocytic leukemia. (882 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
SPARTSpartin. (666 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (770 aa)
RERGRAS like estrogen regulated growth inhibitor. (199 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1583 aa)
SCGB3A1Secretoglobin family 3A member 1. (102 aa)
ENSMNEP00000037716Prohibitin. (236 aa)
INHBAInhibin subunit beta A. (426 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (349 aa)
DCSTAMPDendrocyte expressed seven transmembrane protein. (470 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (833 aa)
MYL2Myosin light chain 2. (166 aa)
SEMA5BSemaphorin 5B. (1150 aa)
ENSMNEP00000036627DCN1-like protein. (276 aa)
ST7LSuppression of tumorigenicity 7 like. (575 aa)
RTN4RReticulon 4 receptor. (522 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (772 aa)
CGRRF1RING-type domain-containing protein. (360 aa)
FHL1Four and a half LIM domains 1. (339 aa)
BCL11ABAF chromatin remodeling complex subunit BCL11A. (838 aa)
MT3Metallothionein 3; Belongs to the metallothionein superfamily. Type 1 family. (115 aa)
SESN2Sestrin 2. (480 aa)
SPHK2Sphingosine kinase 2. (653 aa)
ING1Inhibitor of growth protein. (419 aa)
FSTL4Follistatin like 4. (842 aa)
ARHGAP4Rho GTPase activating protein 4. (946 aa)
SH3BP4SH3 domain binding protein 4. (963 aa)
NDUFA13NADH:ubiquinone oxidoreductase subunit A13. (163 aa)
NPPBNatriuretic peptide B. (132 aa)
ENSMNEP00000032223Prohibitin. (133 aa)
VGLL4Vestigial like family member 4. (296 aa)
BTG1BTG anti-proliferation factor 1. (171 aa)
EI24EI24 autophagy associated transmembrane protein. (340 aa)
GDF2Growth differentiation factor 2. (429 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
DNAJB2DnaJ heat shock protein family (Hsp40) member B2. (324 aa)
MAP2Microtubule-associated protein. (1966 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (528 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (925 aa)
JADE1Jade family PHD finger 1. (858 aa)
CDHR2Cadherin related family member 2. (1306 aa)
NPR1Guanylate cyclase. (1061 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (785 aa)
HRGHistidine rich glycoprotein. (526 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
OSGIN1Oxidative stress induced growth inhibitor 1. (546 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
C10orf90Chromosome 10 open reading frame 90. (796 aa)
HYAL1Hyaluronidase. (435 aa)
DCUN1D3DCN1-like protein. (304 aa)
GDF9Growth differentiation factor 9. (455 aa)
ENSMNEP00000026290Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
ENSMNEP00000026182Prohibitin. (238 aa)
BST2Bone marrow stromal cell antigen 2. (182 aa)
PPT1Palmitoyl-protein thioesterase 1. (335 aa)
EAF2ELL associated factor 2. (263 aa)
SPAG9Sperm associated antigen 9. (1321 aa)
SLIT3Slit guidance ligand 3. (1530 aa)
FRZBFrizzled related protein. (325 aa)
HYAL2Hyaluronidase. (473 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (962 aa)
TSPYL2TSPY like 2; Belongs to the nucleosome assembly protein (NAP) family. (695 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
TP53TG5TP53 target 5. (290 aa)
DCBLD2Discoidin, CUB and LCCL domain containing 2. (789 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (887 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1911 aa)
EPHA7EPH receptor A7. (998 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa)
SIRT1Sirtuin 1. (743 aa)
PPARAPeroxisome proliferator activated receptor alpha. (467 aa)
SOX17SRY-box transcription factor 17. (414 aa)
ENSMNEP00000021373Uncharacterized protein. (72 aa)
ADAM15ADAM metallopeptidase domain 15. (861 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
ULK1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1049 aa)
BCL6BCL6 transcription repressor. (708 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
RGS2Regulator of G protein signaling 2. (211 aa)
CDKN2DCyclin dependent kinase inhibitor 2D. (166 aa)
PPP1R9BProtein phosphatase 1 regulatory subunit 9B. (818 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
MSX1Msh homeobox 1. (303 aa)
ENSMNEP00000017328Uncharacterized protein. (168 aa)
SIPA1Signal-induced proliferation-associated 1. (1042 aa)
OSGIN2Oxidative stress induced growth inhibitor family member 2. (546 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
ENSMNEP00000016907Prohibitin. (173 aa)
RYKReceptor like tyrosine kinase. (606 aa)
CDKN2AIPCDKN2A interacting protein. (580 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (733 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (168 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
BDKRB1Bradykinin receptor B1. (282 aa)
ENSMNEP00000014571Prohibitin. (318 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1677 aa)
G6PDGlucose-6-phosphate dehydrogenase. (561 aa)
RBBP7RB binding protein 7, chromatin remodeling factor. (469 aa)
CCAR2Cell cycle and apoptosis regulator 2. (923 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1035 aa)
SLIT1Slit guidance ligand 1. (1534 aa)
ENSMNEP00000012842Prohibitin. (239 aa)
OSTNOsteocrin. (133 aa)
ENSMNEP00000012285Uncharacterized protein. (451 aa)
RB1RB transcriptional corepressor 1. (928 aa)
NDUFS3NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (265 aa)
ENSMNEP00000011594Uncharacterized protein. (512 aa)
PHBProhibitin. (272 aa)
CAPRIN2Caprin family member 2. (1113 aa)
TCHPTrichoplein keratin filament binding. (498 aa)
PLXNA3Plexin A3. (1871 aa)
RTN4Reticulon. (1118 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (871 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (844 aa)
DAB2DAB adaptor protein 2. (770 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (749 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (975 aa)
PSRC1Proline and serine rich coiled-coil 1. (385 aa)
FOXP1Forkhead box P1. (693 aa)
NTN1Netrin 1. (604 aa)
PRDM11PR/SET domain 11. (1229 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (341 aa)
MINAR1Membrane integral NOTCH2 associated receptor 1. (936 aa)
ENSMNEP00000006880LIM zinc-binding domain-containing protein. (189 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (904 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (760 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
PI16Peptidase inhibitor 16; Belongs to the CRISP family. (468 aa)
CCN3Cellular communication network factor 3. (376 aa)
MYL10Myosin light chain 10. (226 aa)
ENSMNEP00000005266Prohibitin. (198 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (419 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (608 aa)
FLCNFolliculin. (579 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (409 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (697 aa)
SERTAD3SERTA domain containing 3. (196 aa)
SERTAD1SERTA domain containing 1. (236 aa)
ENSMNEP00000002536Prohibitin. (151 aa)
WT1WT1 transcription factor. (517 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
KIAA0319KIAA0319. (1042 aa)
SERTAD2SERTA domain containing 2. (314 aa)
DACT3Dishevelled binding antagonist of beta catenin 3. (547 aa)
ZC3H12DZinc finger CCCH-type containing 12D. (526 aa)
CCDC85BCoiled-coil domain containing 85B. (202 aa)
GAS2L1Growth arrest specific 2 like 1. (681 aa)
RNF6Ring finger protein 6. (701 aa)
NME6Nucleoside diphosphate kinase. (186 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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