39 items (Macaca nemestrina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	THBS1	Thrombospondin 1. (1173 aa)
	CREBBP	CREB binding protein. (2442 aa)
	EP300	E1A binding protein p300. (2397 aa)
	SLC2A10	Solute carrier family 2 member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (642 aa)
	CITED2	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
	ENSMNEP00000030578	PDZ domain-containing protein. (262 aa)
	HIPK2	Homeodomain interacting protein kinase 2. (1198 aa)
	SDCBP	Syndecan binding protein. (318 aa)
	ZEB2	Zinc finger E-box binding homeobox 2. (1253 aa)
	ENSMNEP00000034429	Uncharacterized protein. (291 aa)
	CDKN2B	Cyclin dependent kinase inhibitor 2B. (138 aa)
	AXIN1	Axin 1. (867 aa)
	ENSMNEP00000038155	Uncharacterized protein. (314 aa)
	TGFB1I1	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (467 aa)
	ITGA8	Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
	ENSMNEP00000000865	Uncharacterized protein. (124 aa)
	RNF111	Ring finger protein 111. (1002 aa)
	FLCN	Folliculin. (579 aa)
	SNW1	SNW domain containing 1. (571 aa)
	DAB2	DAB adaptor protein 2. (770 aa)
	STK11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
	ENSMNEP00000012244	Uncharacterized protein. (216 aa)
	C20orf27	Chromosome 20 open reading frame 27. (174 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	ENSMNEP00000013458	PDZ domain-containing protein. (259 aa)
	ADAM17	ADAM metallopeptidase domain 17. (803 aa)
	ENSMNEP00000014831	HATPase_c domain-containing protein. (645 aa)
	GIPC2	GIPC PDZ domain containing family member 2. (319 aa)
	CITED1	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa)
	FERMT1	Fermitin family member 1. (677 aa)
	GIPC3	GIPC PDZ domain containing family member 3. (312 aa)
	MEN1	Menin 1. (610 aa)
	HSP90AB1	Heat shock protein 90 alpha family class B member 1. (724 aa)
	TGFBR3	Transforming growth factor beta receptor 3. (860 aa)
	LRG1	Leucine rich alpha-2-glycoprotein 1. (383 aa)
	ING2	Inhibitor of growth protein. (280 aa)
	MYOCD	Myocardin. (986 aa)
	GIPC1	GIPC PDZ domain containing family member 1. (333 aa)
	CDKN2A	Cyclin dependent kinase inhibitor 2A. (160 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN1	DAB2	ENSMNEP00000037013	ENSMNEP00000009679	Axin 1.	DAB adaptor protein 2.	0.493
AXIN1	HIPK2	ENSMNEP00000037013	ENSMNEP00000031569	Axin 1.	Homeodomain interacting protein kinase 2.	0.656
AXIN1	RNF111	ENSMNEP00000037013	ENSMNEP00000000892	Axin 1.	Ring finger protein 111.	0.562
AXIN1	STK11	ENSMNEP00000037013	ENSMNEP00000010183	Axin 1.	Serine/threonine kinase 11; Belongs to the protein kinase superfamily.	0.624
CDKN2A	CDKN2B	ENSMNEP00000044681	ENSMNEP00000036313	Cyclin dependent kinase inhibitor 2A.	Cyclin dependent kinase inhibitor 2B.	0.746
CDKN2A	ENSMNEP00000000865	ENSMNEP00000044681	ENSMNEP00000000865	Cyclin dependent kinase inhibitor 2A.	Uncharacterized protein.	0.432
CDKN2A	ENSMNEP00000012244	ENSMNEP00000044681	ENSMNEP00000012244	Cyclin dependent kinase inhibitor 2A.	Uncharacterized protein.	0.432
CDKN2B	CDKN2A	ENSMNEP00000036313	ENSMNEP00000044681	Cyclin dependent kinase inhibitor 2B.	Cyclin dependent kinase inhibitor 2A.	0.746
CDKN2B	ENSMNEP00000000865	ENSMNEP00000036313	ENSMNEP00000000865	Cyclin dependent kinase inhibitor 2B.	Uncharacterized protein.	0.485
CDKN2B	ENSMNEP00000012244	ENSMNEP00000036313	ENSMNEP00000012244	Cyclin dependent kinase inhibitor 2B.	Uncharacterized protein.	0.485
CITED1	CREBBP	ENSMNEP00000017652	ENSMNEP00000041109	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	CREB binding protein.	0.704
CITED1	EP300	ENSMNEP00000017652	ENSMNEP00000040649	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	E1A binding protein p300.	0.750
CITED2	CREBBP	ENSMNEP00000030236	ENSMNEP00000041109	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	CREB binding protein.	0.962
CITED2	EP300	ENSMNEP00000030236	ENSMNEP00000040649	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	E1A binding protein p300.	0.972
CREBBP	CITED1	ENSMNEP00000041109	ENSMNEP00000017652	CREB binding protein.	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	0.704
CREBBP	CITED2	ENSMNEP00000041109	ENSMNEP00000030236	CREB binding protein.	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	0.962
CREBBP	EP300	ENSMNEP00000041109	ENSMNEP00000040649	CREB binding protein.	E1A binding protein p300.	0.996
CREBBP	HIPK2	ENSMNEP00000041109	ENSMNEP00000031569	CREB binding protein.	Homeodomain interacting protein kinase 2.	0.566
CREBBP	ING2	ENSMNEP00000041109	ENSMNEP00000046197	CREB binding protein.	Inhibitor of growth protein.	0.598
CREBBP	SMAD4	ENSMNEP00000041109	ENSMNEP00000013301	CREB binding protein.	Mothers against decapentaplegic homolog.	0.764