STRINGSTRING
SMAD6 SMAD6 ENSMNEP00000000212 ENSMNEP00000000212 ITGA8 ITGA8 PARVA PARVA DAG1 DAG1 AXL AXL EPDR1 EPDR1 LOC105493392 LOC105493392 LAMB3 LAMB3 MKLN1 MKLN1 CTNNB1 CTNNB1 ATRN ATRN SIGLEC1 SIGLEC1 STRC STRC ITGAV ITGAV PIP5K1A PIP5K1A SRCIN1 SRCIN1 PARVB PARVB ENSMNEP00000004188 ENSMNEP00000004188 LYVE1 LYVE1 TESK2 TESK2 ITGB1 ITGB1 THY1 THY1 ARHGAP6 ARHGAP6 ADAM9 ADAM9 MEGF9 MEGF9 CD44 CD44 BRAF BRAF FZD7 FZD7 SRC SRC ABL1 ABL1 NID1 NID1 ENSMNEP00000007677 ENSMNEP00000007677 ENSMNEP00000008139 ENSMNEP00000008139 MADCAM1 MADCAM1 CORO2B CORO2B ITGB3 ITGB3 NTNG1 NTNG1 FZD4 FZD4 TMEM8B TMEM8B FN1 FN1 ITGA3 ITGA3 ITGB7 ITGB7 BCAM BCAM COL17A1 COL17A1 VWA2 VWA2 USH2A USH2A BCR BCR TNXB TNXB LAMC3 LAMC3 ITGB2 ITGB2 COL3A1 COL3A1 SORBS1 SORBS1 ANGPTL3 ANGPTL3 ADAMTS12 ADAMTS12 COL5A3 COL5A3 ITGA11 ITGA11 EMP2 EMP2 THSD1 THSD1 EPB41L5 EPB41L5 LOC105493395 LOC105493395 ENSMNEP00000016378 ENSMNEP00000016378 PRKCE PRKCE ITGB6 ITGB6 CD63 CD63 ZYX ZYX WHAMM WHAMM NTNG2 NTNG2 PTK2B PTK2B AP1AR AP1AR BVES BVES AJUBA AJUBA SRGAP2 SRGAP2 BCL6 BCL6 RHOD RHOD FERMT2 FERMT2 CCN2 CCN2 VCL VCL ADAMTS13 ADAMTS13 ADAM15 ADAM15 TRPM7 TRPM7 MERTK MERTK FERMT3 FERMT3 FGA FGA MSLN MSLN FREM1 FREM1 JAM3 JAM3 VCAM1 VCAM1 BCL2 BCL2 ENSMNEP00000023667 ENSMNEP00000023667 ITGA10 ITGA10 CORO1A CORO1A LYPD3 LYPD3 FER FER OTOA OTOA VAMP3 VAMP3 ITGAD ITGAD KIF14 KIF14 ITGA2B ITGA2B ITGAE ITGAE FGB FGB EFNA1 EFNA1 TEK TEK EMILIN1 EMILIN1 MYO1G MYO1G GAS6 GAS6 LPXN LPXN LAMB1 LAMB1 ITGA5 ITGA5 ITGB4 ITGB4 TSC1 TSC1 ITGB8 ITGB8 HPSE HPSE CTTN CTTN ACTN1 ACTN1 DLC1 DLC1 NRP1 NRP1 DDR1 DDR1 PXN PXN TTYH1 TTYH1 SORBS3 SORBS3 FGG FGG ARHGEF7 ARHGEF7 EDA EDA TYRO3 TYRO3 ID1 ID1 CD96 CD96 ITGBL1 ITGBL1 ENSMNEP00000032785 ENSMNEP00000032785 ATRNL1 ATRNL1 ITGA1 ITGA1 FNDC3B FNDC3B TRIP6 TRIP6 HOXD3 HOXD3 ITGA7 ITGA7 RCC2 RCC2 TECTA TECTA LAMA5 LAMA5 ITGAM ITGAM ITGA6 ITGA6 ENSMNEP00000035029 ENSMNEP00000035029 CD34 CD34 TMEFF2 TMEFF2 ANGPT1 ANGPT1 TAOK2 TAOK2 PTPRK PTPRK SRF SRF EPHA1 EPHA1 ADAMTS9 ADAMTS9 EPHB3 EPHB3 PPFIA2 PPFIA2 ENSMNEP00000038197 ENSMNEP00000038197 RHOA RHOA SNED1 SNED1 PPARD PPARD VWF VWF COL13A1 COL13A1 L1CAM L1CAM ANTXR1 ANTXR1 PKD1 PKD1 ITGB5 ITGB5 LAMC1 LAMC1 PARVG PARVG ITGB1BP1 ITGB1BP1 ITGAL ITGAL PEAK1 PEAK1 ITGA4 ITGA4 BCL2L11 BCL2L11 TNN TNN ECM2 ECM2 ACTN3 ACTN3 CCL21 CCL21 CDK5 CDK5 ITGA2 ITGA2 SGCE SGCE ITGAX ITGAX RADIL RADIL ENSMNEP00000044158 ENSMNEP00000044158 ACTN2 ACTN2 NID2 NID2 ATP1B2 ATP1B2 TIAM1 TIAM1 LAMB2 LAMB2 VTN VTN ITGA9 ITGA9 AKIP1 AKIP1 MSLNL MSLNL EPHB1 EPHB1 FAT2 FAT2 THBS3 THBS3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD6Mothers against decapentaplegic homolog. (496 aa)
ENSMNEP00000000212Uncharacterized protein. (175 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
PARVAParvin alpha. (372 aa)
DAG1Dystroglycan 1. (894 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
EPDR1Ependymin related 1. (228 aa)
LOC105493392Uncharacterized protein. (825 aa)
LAMB3Laminin subunit beta 3. (1172 aa)
MKLN1Muskelin 1. (735 aa)
CTNNB1Catenin beta 1. (781 aa)
ATRNAttractin. (1430 aa)
SIGLEC1Sialic acid binding Ig like lectin 1. (1709 aa)
STRCStereocilin. (1732 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1017 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (612 aa)
SRCIN1SRC kinase signaling inhibitor 1. (1272 aa)
PARVBParvin beta. (397 aa)
ENSMNEP00000004188Uncharacterized protein. (778 aa)
LYVE1Lymphatic vessel endothelial hyaluronan receptor 1. (321 aa)
TESK2Testis associated actin remodelling kinase 2. (572 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
THY1Thy-1 cell surface antigen. (161 aa)
ARHGAP6Rho GTPase activating protein 6. (977 aa)
ADAM9ADAM metallopeptidase domain 9. (816 aa)
MEGF9Multiple EGF like domains 9. (619 aa)
CD44CD44 molecule (Indian blood group). (742 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (763 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
SRCTyrosine-protein kinase. (644 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
NID1Nidogen 1. (1226 aa)
ENSMNEP00000007677Uncharacterized protein. (200 aa)
ENSMNEP00000008139Uncharacterized protein. (111 aa)
MADCAM1Mucosal vascular addressin cell adhesion molecule 1. (384 aa)
CORO2BCoronin; Belongs to the WD repeat coronin family. (494 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
NTNG1Netrin G1. (539 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
TMEM8BTransmembrane protein 8B. (472 aa)
FN1Fibronectin 1. (2477 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1064 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (798 aa)
BCAMBasal cell adhesion molecule (Lutheran blood group). (659 aa)
COL17A1Collagen type XVII alpha 1 chain. (1406 aa)
VWA2Uncharacterized protein. (421 aa)
USH2AUsherin. (5210 aa)
BCRBCR activator of RhoGEF and GTPase. (1271 aa)
TNXBTenascin XB. (585 aa)
LAMC3Laminin subunit gamma 3. (1468 aa)
ITGB2Integrin beta. (921 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
SORBS1Sorbin and SH3 domain containing 1. (1277 aa)
ANGPTL3Angiopoietin like 3. (460 aa)
ADAMTS12ADAM metallopeptidase with thrombospondin type 1 motif 12. (1598 aa)
COL5A3Collagen type V alpha 3 chain. (1746 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1213 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
THSD1Thrombospondin type 1 domain containing 1. (853 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (733 aa)
LOC105493395Uncharacterized protein. (905 aa)
ENSMNEP00000016378Protein kinase domain-containing protein. (652 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
CD63Tetraspanin. (238 aa)
ZYXZyxin. (572 aa)
WHAMMWASP homolog associated with actin, golgi membranes and microtubules. (809 aa)
NTNG2Netrin G2. (530 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
AP1ARAdaptor related protein complex 1 associated regulatory protein. (302 aa)
BVESBlood vessel epicardial substance. (360 aa)
AJUBAAjuba LIM protein. (538 aa)
SRGAP2Uncharacterized protein. (1071 aa)
BCL6BCL6 transcription repressor. (708 aa)
RHODRas homolog family member D. (210 aa)
FERMT2Fermitin family member 2. (689 aa)
CCN2Cellular communication network factor 2. (387 aa)
VCLVinculin. (1134 aa)
ADAMTS13ADAM metallopeptidase with thrombospondin type 1 motif 13. (1429 aa)
ADAM15ADAM metallopeptidase domain 15. (861 aa)
TRPM7Transient receptor potential cation channel subfamily M member 7. (1849 aa)
MERTKMER proto-oncogene, tyrosine kinase. (989 aa)
FERMT3Fermitin family member 3. (664 aa)
FGAFibrinogen alpha chain. (862 aa)
MSLNMesothelin. (624 aa)
FREM1FRAS1 related extracellular matrix 1. (2178 aa)
JAM3Junctional adhesion molecule 3. (310 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
ENSMNEP00000023667Uncharacterized protein. (304 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1168 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
LYPD3LY6/PLAUR domain containing 3. (353 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
OTOAOtoancorin. (1139 aa)
VAMP3Vesicle associated membrane protein 3. (100 aa)
ITGADIntegrin subunit alpha D; Belongs to the integrin alpha chain family. (1161 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1647 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1090 aa)
ITGAEIntegrin subunit alpha E; Belongs to the integrin alpha chain family. (1064 aa)
FGBFibrinogen beta chain. (491 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
EMILIN1Elastin microfibril interfacer 1. (1016 aa)
MYO1GMyosin IG; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1018 aa)
GAS6Growth arrest specific 6. (683 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa)
LAMB1Laminin subunit beta 1. (1786 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1098 aa)
ITGB4Integrin beta. (1823 aa)
TSC1TSC complex subunit 1. (1138 aa)
ITGB8Integrin beta. (421 aa)
HPSEHeparanase. (545 aa)
CTTNCortactin. (550 aa)
ACTN1Actinin alpha 1. (914 aa)
DLC1DLC1 Rho GTPase activating protein. (1528 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (925 aa)
DDR1Discoidin domain receptor tyrosine kinase 1. (943 aa)
PXNPaxillin. (1082 aa)
TTYH1Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (460 aa)
SORBS3Sorbin and SH3 domain containing 3. (725 aa)
FGGFibrinogen gamma chain. (437 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (862 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (391 aa)
TYRO3TYRO3 protein tyrosine kinase. (902 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (154 aa)
CD96CD96 molecule. (552 aa)
ITGBL1Integrin subunit beta like 1. (494 aa)
ENSMNEP00000032785PIPK domain-containing protein. (470 aa)
ATRNL1Attractin like 1. (1378 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
FNDC3BFibronectin type III domain containing 3B. (1206 aa)
TRIP6Thyroid hormone receptor interactor 6. (476 aa)
HOXD3Homeobox D3. (432 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1181 aa)
RCC2Regulator of chromosome condensation 2. (508 aa)
TECTATectorin alpha. (2150 aa)
LAMA5Laminin subunit alpha 5. (3696 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1153 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
ENSMNEP00000035029Uncharacterized protein. (1548 aa)
CD34CD34 molecule. (385 aa)
TMEFF2Transmembrane protein with EGF like and two follistatin like domains 2. (374 aa)
ANGPT1Angiopoietin 1. (498 aa)
TAOK2TAO kinase 2. (1236 aa)
PTPRKProtein tyrosine phosphatase receptor type K. (1353 aa)
SRFSerum response factor. (508 aa)
EPHA1EPH receptor A1. (970 aa)
ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif 9. (1935 aa)
EPHB3EPH receptor B3. (1008 aa)
PPFIA2PTPRF interacting protein alpha 2. (1257 aa)
ENSMNEP00000038197Uncharacterized protein. (121 aa)
RHOARas homolog family member A. (193 aa)
SNED1Sushi, nidogen and EGF like domains 1. (1413 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
VWFVon Willebrand factor. (2766 aa)
COL13A1Collagen type XIII alpha 1 chain. (717 aa)
L1CAML1 cell adhesion molecule. (1257 aa)
ANTXR1ANTXR cell adhesion molecule 1. (589 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4303 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (799 aa)
LAMC1Laminin subunit gamma 1. (1608 aa)
PARVGParvin gamma. (331 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1123 aa)
PEAK1Pseudopodium enriched atypical kinase 1. (1746 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
TNNTenascin N. (1299 aa)
ECM2Extracellular matrix protein 2. (700 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (929 aa)
CCL21C-C motif chemokine ligand 21. (131 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
SGCESarcoglycan epsilon. (471 aa)
ITGAXIntegrin subunit alpha X; Belongs to the integrin alpha chain family. (1163 aa)
RADILRap associating with DIL domain. (1096 aa)
ENSMNEP00000044158Protein kinase domain-containing protein. (279 aa)
ACTN2Actinin alpha 2. (894 aa)
NID2Nidogen 2. (1403 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1577 aa)
LAMB2Laminin subunit beta 2. (1798 aa)
VTNSMB domain-containing protein. (479 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1027 aa)
AKIP1A-kinase interacting protein 1. (210 aa)
MSLNLMesothelin like. (767 aa)
EPHB1EPH receptor B1. (984 aa)
FAT2FAT atypical cadherin 2. (4349 aa)
THBS3Thrombospondin 3. (956 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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