STRINGSTRING
ENSMNEP00000006507 ENSMNEP00000006507 SAMM50 SAMM50 TMEM109 TMEM109 ARMC1 ARMC1 ENSMNEP00000024989 ENSMNEP00000024989 PPP1R15A PPP1R15A PGRMC1 PGRMC1 BCL2 BCL2 ENSMNEP00000023358 ENSMNEP00000023358 BAX BAX CYB5B CYB5B STMP1 STMP1 BPHL BPHL CYB5R3 CYB5R3 VAT1 VAT1 TOMM20L TOMM20L ACSL3 ACSL3 ULK1 ULK1 RHOD RHOD SPATA18 SPATA18 DNAJC11 DNAJC11 ENSMNEP00000019939 ENSMNEP00000019939 ENSMNEP00000019763 ENSMNEP00000019763 MICOS10 MICOS10 TOMM20 TOMM20 PTGS2 PTGS2 LOC105489334 LOC105489334 EPHA4 EPHA4 RAC2 RAC2 MGARP MGARP VPS13A VPS13A ENSMNEP00000018013 ENSMNEP00000018013 BNIP3L BNIP3L MTX2 MTX2 SFXN2 SFXN2 PLD6 PLD6 PINK1 PINK1 RAB11FIP5 RAB11FIP5 AGPAT5 AGPAT5 PGAM5 PGAM5 BID BID CYP27B1 CYP27B1 FAM210B FAM210B SYNE1 SYNE1 C11orf65 C11orf65 CLMN CLMN QTRT1 QTRT1 LRPPRC LRPPRC TOMM22 TOMM22 GUCY2D GUCY2D LETMD1 LETMD1 SMPD4 SMPD4 VPS13C VPS13C IMMT IMMT OPA1 OPA1 MSTO1 MSTO1 ENSMNEP00000011616 ENSMNEP00000011616 HK2 HK2 ITPR3 ITPR3 NUTF2 NUTF2 TOMM7 TOMM7 TOMM5 TOMM5 RAB32 RAB32 ENSMNEP00000027345 ENSMNEP00000027345 NIPSNAP2 NIPSNAP2 ZNFX1 ZNFX1 MAOB MAOB RPS27A RPS27A PSEN1 PSEN1 AKAP1 AKAP1 PLA2G2A PLA2G2A SNN SNN CNR2 CNR2 TOMM34 TOMM34 TSPO TSPO ENSMNEP00000011447 ENSMNEP00000011447 GDAP1 GDAP1 ENSMNEP00000010946 ENSMNEP00000010946 ACSL6 ACSL6 DMPK DMPK DNM1L DNM1L ENSMNEP00000028288 ENSMNEP00000028288 CPT1A CPT1A SLC11A2 SLC11A2 MARCHF5 MARCHF5 GK2 GK2 CPTP CPTP ENSMNEP00000029065 ENSMNEP00000029065 SYNE3 SYNE3 ATF2 ATF2 ENSMNEP00000029354 ENSMNEP00000029354 MARC2 MARC2 ARMCX1 ARMCX1 ENSMNEP00000029611 ENSMNEP00000029611 SLC25A46 SLC25A46 TAZ TAZ EXD2 EXD2 CPT1B CPT1B THG1L THG1L ACSL5 ACSL5 SPIRE1 SPIRE1 ENSMNEP00000030542 ENSMNEP00000030542 RHOT2 RHOT2 STARD7 STARD7 PPP1CC PPP1CC FATE1 FATE1 BNIP5 BNIP5 ENSMNEP00000031409 ENSMNEP00000031409 MFF MFF SIGMAR1 SIGMAR1 ARG1 ARG1 MIGA1 MIGA1 QTRT2 QTRT2 ENSMNEP00000010831 ENSMNEP00000010831 SYNE4 SYNE4 LPIN1 LPIN1 ATAD1 ATAD1 BAK1 BAK1 LRRK2 LRRK2 BOK BOK IFI27 IFI27 MTOR MTOR ENSMNEP00000010027 ENSMNEP00000010027 WASF1 WASF1 ENSMNEP00000009513 ENSMNEP00000009513 ENSMNEP00000009334 ENSMNEP00000009334 MTCH1 MTCH1 DMD DMD GPAT2 GPAT2 HK1 HK1 TIGAR TIGAR ENSMNEP00000007244 ENSMNEP00000007244 TRIM14 TRIM14 ENSMNEP00000006959 ENSMNEP00000006959 ENSMNEP00000006854 ENSMNEP00000006854 ENSMNEP00000006846 ENSMNEP00000006846 TRAF3IP3 TRAF3IP3 PRKN PRKN BMF BMF TOMM40L TOMM40L BNIP3 BNIP3 MYOC MYOC PI4KB PI4KB ENSMNEP00000005892 ENSMNEP00000005892 ENSMNEP00000005796 ENSMNEP00000005796 FIS1 FIS1 BCL2L10 BCL2L10 ACSL1 ACSL1 APOO APOO MAOA MAOA MTCH2 MTCH2 MOAP1 MOAP1 TOMM70 TOMM70 PDE2A PDE2A FUNDC2 FUNDC2 RETSAT-2 RETSAT-2 VDAC1 VDAC1 ENSMNEP00000003216 ENSMNEP00000003216 BCL2L1 BCL2L1 ENSMNEP00000002753 ENSMNEP00000002753 PLEC PLEC ENSMNEP00000002165 ENSMNEP00000002165 BBC3 BBC3 MTX3 MTX3 ENSMNEP00000043182 ENSMNEP00000043182 ENSMNEP00000043126 ENSMNEP00000043126 HINT2 HINT2 MIGA2 MIGA2 ASS1 ASS1 GHRHR GHRHR ACSL4 ACSL4 SLC44A1 SLC44A1 BCL2L11 BCL2L11 AIFM2 AIFM2 MIEF1 MIEF1 USP30 USP30 RETSAT RETSAT NAV3 NAV3 KMO KMO RHOT1 RHOT1 DHCR7 DHCR7 MIEF2 MIEF2 ENSMNEP00000040888 ENSMNEP00000040888 ENSMNEP00000040501 ENSMNEP00000040501 MYO19 MYO19 MUL1 MUL1 ENSMNEP00000040106 ENSMNEP00000040106 RMDN3 RMDN3 EMD EMD MGST1 MGST1 SPART SPART LTC4S LTC4S CPT1C CPT1C COASY COASY RNF185 RNF185 BCL2A1 BCL2A1 ENSMNEP00000038250 ENSMNEP00000038250 ENSMNEP00000038142 ENSMNEP00000038142 ENSMNEP00000038074 ENSMNEP00000038074 NEU4 NEU4 HAX1 HAX1 CHCHD6 CHCHD6 CHCHD3 CHCHD3 TOMM40 TOMM40 AMBRA1 AMBRA1 ARMC12 ARMC12 GPAM GPAM CISD2 CISD2 MLXIP MLXIP MFN1 MFN1 SLC8A3 SLC8A3 ABCB6 ABCB6 ENSMNEP00000035304 ENSMNEP00000035304 DAO DAO ENSMNEP00000035145 ENSMNEP00000035145 SARM1 SARM1 GUCY2F GUCY2F NLRX1 NLRX1 RSAD2 RSAD2 FUNDC1 FUNDC1 MTX1 MTX1 CCDC155 CCDC155 SOX10 SOX10 ENSMNEP00000033567 ENSMNEP00000033567 VDAC3 VDAC3 SH3GLB1 SH3GLB1 CASP8 CASP8 GK GK ENSMNEP00000032293 ENSMNEP00000032293 MTERF3 MTERF3 STING1 STING1 CISD1 CISD1 MCL1 MCL1 KRAS KRAS RPS6KB1 RPS6KB1 ENSMNEP00000045036 ENSMNEP00000045036 RTN4IP1 RTN4IP1 HADHB HADHB ENSMNEP00000044600 ENSMNEP00000044600 ACACB ACACB MFN2 MFN2 BAD BAD MTARC1 MTARC1 SPATA19 SPATA19 VDAC2 VDAC2 ENSMNEP00000043248 ENSMNEP00000043248 ENSMNEP00000043194 ENSMNEP00000043194
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMNEP00000006507Uncharacterized protein. (74 aa)
SAMM50SAMM50 sorting and assembly machinery component. (497 aa)
TMEM109Transmembrane protein 109. (243 aa)
ARMC1Armadillo repeat-containing protein 1. (282 aa)
ENSMNEP00000024989KASH domain-containing protein. (3507 aa)
PPP1R15AProtein phosphatase 1 regulatory subunit 15A. (674 aa)
PGRMC1Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family. (195 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
ENSMNEP00000023358Uncharacterized protein. (65 aa)
BAXBCL2 associated X, apoptosis regulator. (203 aa)
CYB5BCytochrome b5 type B; Belongs to the cytochrome b5 family. (150 aa)
STMP1Short transmembrane mitochondrial protein 1. (47 aa)
BPHLBiphenyl hydrolase like. (291 aa)
CYB5R3NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (333 aa)
VAT1Vesicle amine transport 1. (401 aa)
TOMM20LTranslocase of outer mitochondrial membrane 20 like. (152 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (715 aa)
ULK1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1049 aa)
RHODRas homolog family member D. (210 aa)
SPATA18Spermatogenesis associated 18. (538 aa)
DNAJC11DnaJ heat shock protein family (Hsp40) member C11. (559 aa)
ENSMNEP00000019939MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (166 aa)
ENSMNEP00000019763Uncharacterized protein. (285 aa)
MICOS10MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (78 aa)
TOMM20Translocase of outer mitochondrial membrane 20. (145 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
LOC105489334Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (134 aa)
EPHA4EPH receptor A4. (997 aa)
RAC2Rac family small GTPase 2. (192 aa)
MGARPMitochondria localized glutamic acid rich protein. (240 aa)
VPS13AVacuolar protein sorting 13 homolog A. (3052 aa)
ENSMNEP00000018013Uncharacterized protein. (243 aa)
BNIP3LBCL2 interacting protein 3 like. (219 aa)
MTX2Metaxin 2. (263 aa)
SFXN2Sidoreflexin. (322 aa)
PLD6Phospholipase D family member 6. (224 aa)
PINK1PTEN induced kinase 1. (581 aa)
RAB11FIP5Uncharacterized protein. (1319 aa)
AGPAT51-acylglycerol-3-phosphate O-acyltransferase 5. (364 aa)
PGAM5Uncharacterized protein. (140 aa)
BIDBH3 interacting domain death agonist. (266 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
FAM210BFamily with sequence similarity 210 member B. (192 aa)
SYNE1Spectrin repeat containing nuclear envelope protein 1. (8797 aa)
C11orf65Chromosome 11 open reading frame 65. (313 aa)
CLMNCalmin. (1002 aa)
QTRT1Queuine tRNA-ribosyltransferase catalytic subunit 1. (338 aa)
LRPPRCPPR_long domain-containing protein. (1397 aa)
TOMM22Translocase of outer mitochondrial membrane 22. (142 aa)
GUCY2DGuanylate cyclase. (1103 aa)
LETMD1LETM1 domain containing 1. (362 aa)
SMPD4Sphingomyelin phosphodiesterase 4. (835 aa)
VPS13CVacuolar protein sorting 13 homolog C. (3754 aa)
IMMTMICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (758 aa)
OPA1OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1015 aa)
MSTO1Misato mitochondrial distribution and morphology regulator 1. (569 aa)
ENSMNEP00000011616Uncharacterized protein. (119 aa)
HK2Hexokinase 2. (917 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
NUTF2NTF2 domain-containing protein. (127 aa)
TOMM7Uncharacterized protein. (126 aa)
TOMM5Translocase of outer mitochondrial membrane 5. (91 aa)
RAB32Uncharacterized protein. (225 aa)
ENSMNEP00000027345Uncharacterized protein. (71 aa)
NIPSNAP2Nipsnap homolog 2. (239 aa)
ZNFX1Zinc finger NFX1-type containing 1. (1927 aa)
MAOBAmine oxidase. (520 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
AKAP1A-kinase anchoring protein 1. (908 aa)
PLA2G2APhospholipase A(2). (144 aa)
SNNStannin. (88 aa)
CNR2Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. (360 aa)
TOMM34Translocase of outer mitochondrial membrane 34. (309 aa)
TSPOTranslocator protein. (169 aa)
ENSMNEP00000011447Uncharacterized protein. (427 aa)
GDAP1Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily. (358 aa)
ENSMNEP00000010946Uncharacterized protein. (423 aa)
ACSL6AMP-binding domain-containing protein. (725 aa)
DMPKDM1 protein kinase. (630 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (802 aa)
ENSMNEP00000028288NTF2 domain-containing protein. (127 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
SLC11A2Solute carrier family 11 member 2. (568 aa)
MARCHF5Membrane associated ring-CH-type finger 5. (278 aa)
GK2Glycerol kinase 2; Belongs to the FGGY kinase family. (553 aa)
CPTPCeramide-1-phosphate transfer protein. (214 aa)
ENSMNEP00000029065Uncharacterized protein. (62 aa)
SYNE3Spectrin repeat containing nuclear envelope family member 3. (975 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
ENSMNEP00000029354MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (227 aa)
MARC2Mitochondrial amidoxime reducing component 2. (335 aa)
ARMCX1Armadillo repeat containing X-linked 1. (453 aa)
ENSMNEP00000029611Uncharacterized protein. (117 aa)
SLC25A46Solute carrier family 25 member 46; Belongs to the mitochondrial carrier (TC 2.A.29) family. (418 aa)
TAZTafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (292 aa)
EXD2Exonuclease 3'-5' domain containing 2. (620 aa)
CPT1BCarnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
THG1LtRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (298 aa)
ACSL5Acyl-CoA synthetase long chain family member 5. (683 aa)
SPIRE1Spire type actin nucleation factor 1. (710 aa)
ENSMNEP00000030542Uncharacterized protein. (361 aa)
RHOT2Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (618 aa)
STARD7StAR related lipid transfer domain containing 7. (370 aa)
PPP1CCSerine/threonine-protein phosphatase. (293 aa)
FATE1Fetal and adult testis expressed 1. (183 aa)
BNIP5BCL2 interacting protein 5. (647 aa)
ENSMNEP00000031409DUF1279 domain-containing protein. (193 aa)
MFFMitochondrial fission factor. (341 aa)
SIGMAR1Sigma non-opioid intracellular receptor 1. (223 aa)
ARG1Arginase. (322 aa)
MIGA1Mitoguardin 1. (638 aa)
QTRT2Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. (415 aa)
ENSMNEP00000010831Uncharacterized protein. (243 aa)
SYNE4Spectrin repeat containing nuclear envelope family member 4. (404 aa)
LPIN1Lipin 1. (975 aa)
ATAD1AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
LRRK2Leucine rich repeat kinase 2. (2512 aa)
BOKBCL2 family apoptosis regulator BOK. (212 aa)
IFI27Uncharacterized protein. (122 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2546 aa)
ENSMNEP00000010027Uncharacterized protein. (129 aa)
WASF1WASP family member 1. (559 aa)
ENSMNEP00000009513Uncharacterized protein. (89 aa)
ENSMNEP00000009334Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (156 aa)
MTCH1Mitochondrial carrier 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (389 aa)
DMDDystrophin. (3685 aa)
GPAT2Glycerol-3-phosphate acyltransferase 2, mitochondrial. (795 aa)
HK1Hexokinase 1. (921 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
ENSMNEP00000007244Uncharacterized protein. (128 aa)
TRIM14Tripartite motif containing 14. (442 aa)
ENSMNEP00000006959Uncharacterized protein. (262 aa)
ENSMNEP00000006854Uncharacterized protein. (164 aa)
ENSMNEP00000006846Miff domain-containing protein. (78 aa)
TRAF3IP3TRAF3 interacting protein 3. (551 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
BMFBcl2 modifying factor. (184 aa)
TOMM40LTranslocase of outer mitochondrial membrane 40 like. (308 aa)
BNIP3BCL2 interacting protein 3. (253 aa)
MYOCMyocilin. (491 aa)
PI4KBPhosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family. (832 aa)
ENSMNEP00000005892Ubiquitin-like domain-containing protein. (156 aa)
ENSMNEP00000005796Ribosomal_S27 domain-containing protein. (137 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
BCL2L10Uncharacterized protein. (194 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (698 aa)
APOOMICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (198 aa)
MAOAAmine oxidase. (527 aa)
MTCH2Mitochondrial carrier 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
MOAP1Modulator of apoptosis 1. (351 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (608 aa)
PDE2APhosphodiesterase. (942 aa)
FUNDC2FUN14 domain containing 2. (189 aa)
RETSAT-2Retinol saturase. (146 aa)
VDAC1Uncharacterized protein. (321 aa)
ENSMNEP00000003216NTF2 domain-containing protein. (119 aa)
BCL2L1BCL2 like 1. (233 aa)
ENSMNEP00000002753Ubiquitin-like domain-containing protein. (156 aa)
PLECPlectin. (4774 aa)
ENSMNEP00000002165MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (598 aa)
BBC3BCL2 binding component 3. (261 aa)
MTX3Metaxin. (312 aa)
ENSMNEP00000043182MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (160 aa)
ENSMNEP00000043126Thiolase_N domain-containing protein. (396 aa)
HINT2Histidine triad nucleotide binding protein 2. (163 aa)
MIGA2Mitoguardin 2. (574 aa)
ASS1Argininosuccinate synthase 1. (412 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (464 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (711 aa)
SLC44A1Solute carrier family 44 member 1; Belongs to the CTL (choline transporter-like) family. (657 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
AIFM2Apoptosis inducing factor mitochondria associated 2. (373 aa)
MIEF1Mitochondrial elongation factor 1. (478 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (517 aa)
RETSATRetinol saturase. (610 aa)
NAV3Neuron navigator 3. (2383 aa)
KMOKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (470 aa)
RHOT1Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (658 aa)
DHCR77-dehydrocholesterol reductase. (475 aa)
MIEF2Mitochondrial elongation factor 2. (454 aa)
ENSMNEP00000040888Uncharacterized protein. (375 aa)
ENSMNEP00000040501AAA domain-containing protein; Belongs to the AAA ATPase family. (342 aa)
MYO19Myosin XIX; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (962 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
ENSMNEP00000040106Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (436 aa)
RMDN3Regulator of microtubule dynamics 3. (462 aa)
EMDEmerin. (258 aa)
MGST1Microsomal glutathione S-transferase 1. (155 aa)
SPARTSpartin. (666 aa)
LTC4SLeukotriene C4 synthase. (150 aa)
CPT1CCarnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (803 aa)
COASYCoenzyme A synthase. (564 aa)
RNF185Ring finger protein 185. (192 aa)
BCL2A1BCL2 related protein A1. (175 aa)
ENSMNEP00000038250ZnF_CDGSH domain-containing protein. (95 aa)
ENSMNEP00000038142Uncharacterized protein. (194 aa)
ENSMNEP00000038074FGGY_N domain-containing protein. (130 aa)
NEU4Neuraminidase 4. (496 aa)
HAX1HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (279 aa)
CHCHD6MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (255 aa)
CHCHD3MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (242 aa)
TOMM40Translocase of outer mitochondrial membrane 40. (361 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1298 aa)
ARMC12Armadillo repeat containing 12. (367 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
CISD2CDGSH iron sulfur domain 2. (142 aa)
MLXIPMLX interacting protein. (919 aa)
MFN1Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (688 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (928 aa)
ABCB6ATP binding cassette subfamily B member 6 (Langereis blood group). (856 aa)
ENSMNEP00000035304Ubiquitin-like domain-containing protein. (134 aa)
DAOD-amino acid oxidase. (352 aa)
ENSMNEP00000035145ZnF_CDGSH domain-containing protein. (92 aa)
SARM1Sterile alpha and TIR motif containing 1. (724 aa)
GUCY2FGuanylate cyclase. (1108 aa)
NLRX1NLR family member X1. (972 aa)
RSAD2Radical S-adenosyl methionine domain containing 2. (360 aa)
FUNDC1FUN14 domain containing 1. (155 aa)
MTX1Metaxin 1. (478 aa)
CCDC155Coiled-coil domain containing 155. (575 aa)
SOX10SRY-box transcription factor 10. (467 aa)
ENSMNEP00000033567MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (220 aa)
VDAC3Voltage dependent anion channel 3. (284 aa)
SH3GLB1SH3 domain containing GRB2 like, endophilin B1. (402 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (487 aa)
GKUncharacterized protein; Belongs to the FGGY kinase family. (564 aa)
ENSMNEP00000032293Armadillo repeat-containing protein 1. (252 aa)
MTERF3Mitochondrial transcription termination factor 3. (417 aa)
STING1Transmembrane protein 173. (379 aa)
CISD1CDGSH iron sulfur domain 1. (108 aa)
MCL1MCL1 apoptosis regulator, BCL2 family member. (350 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
ENSMNEP00000045036ZnF_CDGSH domain-containing protein. (103 aa)
RTN4IP1Reticulon 4 interacting protein 1. (396 aa)
HADHBHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (471 aa)
ENSMNEP00000044600NTF2 domain-containing protein. (120 aa)
ACACBAcetyl-CoA carboxylase beta. (2458 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
BADBCL2 associated agonist of cell death. (167 aa)
MTARC1MOSC domain-containing protein. (337 aa)
SPATA19Spermatogenesis associated 19. (167 aa)
VDAC2Voltage dependent anion channel 2. (308 aa)
ENSMNEP00000043248Uncharacterized protein. (82 aa)
ENSMNEP00000043194NTF2 domain-containing protein. (120 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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