86 items (Macaca nemestrina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ARFIP2	ADP ribosylation factor interacting protein 2. (341 aa)
	LGR5	Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
	KIF13A	Kinesin family member 13A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1849 aa)
	LOC105474413	Ig-like domain-containing protein. (295 aa)
	STX16	Syntaxin 16; Belongs to the syntaxin family. (325 aa)
	SCAMP3	Secretory carrier-associated membrane protein. (347 aa)
	AP4M1	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (454 aa)
	ATP2C2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (977 aa)
	RAB9A	RAB9A, member RAS oncogene family. (201 aa)
	LOC105470579	Uncharacterized protein. (245 aa)
	ARL1	ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
	GOLPH3L	Golgi phosphoprotein 3 like. (285 aa)
	ENSMNEP00000002245	Ig-like domain-containing protein. (232 aa)
	CLBA1	Clathrin binding box of aftiphilin containing 1. (325 aa)
	ATP7A	ATPase copper transporting alpha. (1500 aa)
	LOC105470433	MHC class II antigen. (260 aa)
	RIC1	RIC1 homolog, RAB6A GEF complex partner 1. (1343 aa)
	GCC2	GRIP and coiled-coil domain containing 2. (1674 aa)
	ATP9A	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1107 aa)
	VAMP4	Vesicle associated membrane protein 4. (172 aa)
	CLTC	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
	MMP24	Matrix metallopeptidase 24. (603 aa)
	SCAMP1	Secretory carrier-associated membrane protein. (338 aa)
	COG2	Component of oligomeric golgi complex 2. (738 aa)
	AP1S2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa)
	COG3	Component of oligomeric golgi complex 3. (828 aa)
	BAIAP3	BAI1 associated protein 3. (1191 aa)
	M6PR	Mannose-6-phosphate receptor, cation dependent. (278 aa)
	RAB43	RAB43, member RAS oncogene family. (212 aa)
	VPS13B	Vacuolar protein sorting 13 homolog B. (4022 aa)
	TMEM165	GDT1 family protein. (326 aa)
	SLC30A6	Solute carrier family 30 member 6. (461 aa)
	BOK	BCL2 family apoptosis regulator BOK. (212 aa)
	HLA-DPB1	Major histocompatibility complex, class II, DP beta 1. (268 aa)
	NSG2	Neuronal vesicle trafficking associated 2. (171 aa)
	COG5	Component of oligomeric golgi complex 5. (860 aa)
	RGP1	RGP1 homolog, RAB6A GEF complex partner 1. (391 aa)
	ATP7B	ATPase copper transporting beta. (1465 aa)
	IMPAD1	Inositol monophosphatase domain containing 1. (304 aa)
	SLC24A5	Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (500 aa)
	MLANA	Melan-A. (118 aa)
	SCAMP2	Secretory carrier-associated membrane protein. (329 aa)
	VPS54	VPS54 subunit of GARP complex. (966 aa)
	VPS51	VPS51 subunit of GARP complex. (766 aa)
	RAB31	RAB31, member RAS oncogene family. (194 aa)
	LLGL1	LLGL scribble cell polarity complex component 1. (1049 aa)
	VTI1A	Vesicle transport through interaction with t-SNAREs 1A. (217 aa)
	LGR6	Leucine rich repeat containing G protein-coupled receptor 6. (920 aa)
	CRACR2A	Calcium release activated channel regulator 2A. (731 aa)
	USP6NL	USP6 N-terminal like. (851 aa)
	COG1	Component of oligomeric golgi complex 1. (980 aa)
	ARFIP1	ADP ribosylation factor interacting protein 1. (373 aa)
	AP1B1	AP complex subunit beta. (949 aa)
	CALN1	Calneuron 1. (261 aa)
	ST3GAL1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (340 aa)
	IGF2R	Insulin like growth factor 2 receptor. (2491 aa)
	TGOLN2	Trans-golgi network protein 2. (417 aa)
	AP1S1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
	GNAS	GNAS complex locus. (1007 aa)
	AP4E1	AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. (1137 aa)
	ENSMNEP00000022897	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (144 aa)
	NDST1	N-deacetylase and N-sulfotransferase 1. (882 aa)
	PLD4	Phospholipase D family member 4. (515 aa)
	COG7	Component of oligomeric golgi complex 7. (770 aa)
	STX6	Syntaxin 6; Belongs to the syntaxin family. (255 aa)
	CD74	CD74 molecule. (294 aa)
	SCAMP5	Secretory carrier-associated membrane protein. (243 aa)
	HTR7	5-hydroxytryptamine receptor 7; Belongs to the G-protein coupled receptor 1 family. (480 aa)
	VPS52	VPS52 subunit of GARP complex. (723 aa)
	CLIP3	CAP-Gly domain containing linker protein 3. (566 aa)
	RHOBTB3	Rho related BTB domain containing 3. (611 aa)
	STX10	Syntaxin 10; Belongs to the syntaxin family. (249 aa)
	AP4S1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (137 aa)
	TMEM79	Transmembrane protein 79. (394 aa)
	AFTPH	Aftiphilin. (935 aa)
	CLTA	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (236 aa)
	HLA-DPA1	Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa)
	CABP7	Calcium binding protein 7. (215 aa)
	MARCHF1	Membrane associated ring-CH-type finger 1. (545 aa)
	AP4B1	AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (739 aa)
	AP1S3	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (164 aa)
	AP1M2	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (400 aa)
	RABEPK	Rab9 effector protein with kelch motifs. (331 aa)
	COG6	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. (690 aa)
	NSG1	Neuronal vesicle trafficking associated 1. (185 aa)
	TEPSIN	TEPSIN adaptor related protein complex 4 accessory protein. (595 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFTPH	AP1B1	ENSMNEP00000035336	ENSMNEP00000017672	Aftiphilin.	AP complex subunit beta.	0.418
AFTPH	AP1M2	ENSMNEP00000035336	ENSMNEP00000038518	Aftiphilin.	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.731
AFTPH	AP1S1	ENSMNEP00000035336	ENSMNEP00000021066	Aftiphilin.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.560
AFTPH	AP1S2	ENSMNEP00000035336	ENSMNEP00000007688	Aftiphilin.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.747
AFTPH	AP1S3	ENSMNEP00000035336	ENSMNEP00000037692	Aftiphilin.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.624
AFTPH	AP4E1	ENSMNEP00000035336	ENSMNEP00000021946	Aftiphilin.	AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.	0.404
AFTPH	AP4M1	ENSMNEP00000035336	ENSMNEP00000043935	Aftiphilin.	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]	0.605
AFTPH	CLTC	ENSMNEP00000035336	ENSMNEP00000005668	Aftiphilin.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.421
AP1B1	AFTPH	ENSMNEP00000017672	ENSMNEP00000035336	AP complex subunit beta.	Aftiphilin.	0.418
AP1B1	AP1M2	ENSMNEP00000017672	ENSMNEP00000038518	AP complex subunit beta.	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.989
AP1B1	AP1S1	ENSMNEP00000017672	ENSMNEP00000021066	AP complex subunit beta.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.995
AP1B1	AP1S2	ENSMNEP00000017672	ENSMNEP00000007688	AP complex subunit beta.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.992
AP1B1	AP1S3	ENSMNEP00000017672	ENSMNEP00000037692	AP complex subunit beta.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.998
AP1B1	AP4B1	ENSMNEP00000017672	ENSMNEP00000036838	AP complex subunit beta.	AP complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.649
AP1B1	AP4E1	ENSMNEP00000017672	ENSMNEP00000021946	AP complex subunit beta.	AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.	0.908
AP1B1	AP4M1	ENSMNEP00000017672	ENSMNEP00000043935	AP complex subunit beta.	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]	0.886
AP1B1	AP4S1	ENSMNEP00000017672	ENSMNEP00000034277	AP complex subunit beta.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.723
AP1B1	CD74	ENSMNEP00000017672	ENSMNEP00000026164	AP complex subunit beta.	CD74 molecule.	0.483
AP1B1	CLTA	ENSMNEP00000017672	ENSMNEP00000035340	AP complex subunit beta.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.905
AP1B1	CLTC	ENSMNEP00000017672	ENSMNEP00000005668	AP complex subunit beta.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.907