Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BPI | TLR4 | ENSMNEP00000036142 | ENSMNEP00000035110 | Bactericidal permeability increasing protein. | Toll like receptor 4; Belongs to the Toll-like receptor family. | 0.486 |
| CD84 | NCKAP1L | ENSMNEP00000032639 | ENSMNEP00000012123 | CD84 molecule. | NCK associated protein 1 like. | 0.418 |
| CSK | PTPN22 | ENSMNEP00000023214 | ENSMNEP00000012016 | Tyrosine-protein kinase. | Protein tyrosine phosphatase non-receptor type 22. | 0.962 |
| CSK | PTPN6 | ENSMNEP00000023214 | ENSMNEP00000029848 | Tyrosine-protein kinase. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.599 |
| CX3CL1 | IL10 | ENSMNEP00000018858 | ENSMNEP00000036763 | C-X3-C motif chemokine ligand 1. | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.406 |
| ENSMNEP00000007269 | RABGEF1 | ENSMNEP00000007269 | ENSMNEP00000041503 | VPS9 domain-containing protein. | A20-type domain-containing protein. | 0.619 |
| FOXP3 | IL10 | ENSMNEP00000024682 | ENSMNEP00000036763 | Forkhead box P3. | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.831 |
| FOXP3 | TLR4 | ENSMNEP00000024682 | ENSMNEP00000035110 | Forkhead box P3. | Toll like receptor 4; Belongs to the Toll-like receptor family. | 0.584 |
| FOXP3 | TNF | ENSMNEP00000024682 | ENSMNEP00000029202 | Forkhead box P3. | Tumor necrosis factor; Belongs to the tumor necrosis factor family. | 0.679 |
| GHRL | GHSR | ENSMNEP00000042177 | ENSMNEP00000014840 | Ghrelin and obestatin prepropeptide. | Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. | 0.996 |
| GHSR | GHRL | ENSMNEP00000014840 | ENSMNEP00000042177 | Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. | Ghrelin and obestatin prepropeptide. | 0.996 |
| HAVCR2 | IL10 | ENSMNEP00000036358 | ENSMNEP00000036763 | Hepatitis A virus cellular receptor 2. | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.528 |
| HAVCR2 | PTPN6 | ENSMNEP00000036358 | ENSMNEP00000029848 | Hepatitis A virus cellular receptor 2. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.414 |
| HGF | IL10 | ENSMNEP00000033889 | ENSMNEP00000036763 | Hepatocyte growth factor; Belongs to the peptidase S1 family. | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.615 |
| IL10 | CX3CL1 | ENSMNEP00000036763 | ENSMNEP00000018858 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | C-X3-C motif chemokine ligand 1. | 0.406 |
| IL10 | FOXP3 | ENSMNEP00000036763 | ENSMNEP00000024682 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | Forkhead box P3. | 0.831 |
| IL10 | HAVCR2 | ENSMNEP00000036763 | ENSMNEP00000036358 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | Hepatitis A virus cellular receptor 2. | 0.528 |
| IL10 | HGF | ENSMNEP00000036763 | ENSMNEP00000033889 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | Hepatocyte growth factor; Belongs to the peptidase S1 family. | 0.615 |
| IL10 | IL27RA | ENSMNEP00000036763 | ENSMNEP00000044094 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | Interleukin 27 receptor subunit alpha. | 0.799 |
| IL10 | TLR4 | ENSMNEP00000036763 | ENSMNEP00000035110 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | Toll like receptor 4; Belongs to the Toll-like receptor family. | 0.747 |
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