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TIRAP | TIR domain containing adaptor protein. (234 aa) | ||||
APP | Amyloid beta precursor protein. (770 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa) | ||||
OAS3 | 2'-5'-oligoadenylate synthetase 3. (1076 aa) | ||||
IL6R | Interleukin 6 receptor. (467 aa) | ||||
OAS1 | 2'-5'-oligoadenylate synthetase 1. (488 aa) | ||||
EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (545 aa) | ||||
TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa) | ||||
HIF1A | Hypoxia inducible factor 1 subunit alpha. (826 aa) | ||||
ALOX15B | Arachidonate 15-lipoxygenase type B. (676 aa) | ||||
ADIPOQ | Adiponectin, C1Q and collagen domain containing. (274 aa) | ||||
IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) | ||||
RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa) | ||||
IL33 | Interleukin 33. (270 aa) | ||||
PYCARD | PYD and CARD domain containing. (195 aa) | ||||
HAVCR2 | Hepatitis A virus cellular receptor 2. (294 aa) | ||||
CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa) | ||||
IL17A | Interleukin 17A. (155 aa) | ||||
MIF | Macrophage migration inhibitory factor. (115 aa) | ||||
TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (826 aa) | ||||
CLEC7A | C-type lectin domain containing 7A. (247 aa) | ||||
EIF2AK2 | Eukaryotic translation initiation factor 2 alpha kinase 2. (488 aa) | ||||
IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa) | ||||
CD84 | CD84 molecule. (345 aa) | ||||
MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa) | ||||
IL17F | Interleukin 17F. (163 aa) | ||||
IL7 | Interleukin 7. (184 aa) | ||||
TICAM1 | Toll like receptor adaptor molecule 1. (519 aa) | ||||
TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) | ||||
SYK | Tyrosine-protein kinase. (629 aa) | ||||
TLR7 | Toll like receptor 7; Belongs to the Toll-like receptor family. (1049 aa) | ||||
AIF1 | Allograft inflammatory factor 1. (147 aa) | ||||
CD74 | CD74 molecule. (294 aa) | ||||
IL17RA | Interleukin 17 receptor A. (865 aa) | ||||
TNFSF4 | TNF superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa) | ||||
LBP | Lipopolysaccharide binding protein. (481 aa) | ||||
DEFB124 | Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (73 aa) | ||||
ADCYAP1 | Adenylate cyclase activating polypeptide 1. (176 aa) | ||||
LPL | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa) | ||||
AZU1 | Azurocidin 1. (250 aa) | ||||
ENSMNEP00000018637 | Uncharacterized protein. (309 aa) | ||||
AGER | Advanced glycosylation end-product specific receptor. (414 aa) | ||||
CHIA | Chitinase acidic; Belongs to the glycosyl hydrolase 18 family. (470 aa) | ||||
TSLP | Thymic stromal lymphopoietin. (159 aa) | ||||
NOD2 | Nucleotide binding oligomerization domain containing 2. (1044 aa) | ||||
IL4R | Interleukin 4 receptor. (825 aa) | ||||
ADORA2B | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (331 aa) | ||||
DDX3X | DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (733 aa) | ||||
MCOLN2 | Mucolipin 2. (566 aa) | ||||
TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa) | ||||
ADAM17 | ADAM metallopeptidase domain 17. (803 aa) | ||||
CARD9 | Caspase recruitment domain family member 9. (535 aa) | ||||
ENSMNEP00000010344 | Uncharacterized protein. (206 aa) | ||||
HMGB1 | High mobility group box 1. (215 aa) | ||||
FFAR2 | Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (330 aa) | ||||
WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (419 aa) | ||||
AIRE | Autoimmune regulator. (542 aa) | ||||
TRIM32 | Tripartite motif containing 32. (596 aa) | ||||
C5 | Complement C5. (1676 aa) | ||||
MBP | Myelin basic protein. (330 aa) | ||||
IL6 | Interleukin 6. (214 aa) |