STRINGSTRING
CDC73 CDC73 MED29 MED29 MED23 MED23 CCNK CCNK ELL3 ELL3 MED8 MED8 EAPP EAPP MED9 MED9 MED27 MED27 ENSMNEP00000019186 ENSMNEP00000019186 MED11 MED11 BTBD18 BTBD18 MED19 MED19 MED22 MED22 MED14 MED14 BRD4 BRD4 MED30 MED30 MED24 MED24 CDK12 CDK12 LOC105498354 LOC105498354 MED7 MED7 TCERG1 TCERG1 CTNNB1 CTNNB1 CCNT2 CCNT2 SUPT16H SUPT16H PWWP2B PWWP2B CCNT1 CCNT1 MED16 MED16 SUPT6H SUPT6H ELL ELL MED31 MED31 MED15 MED15 CDK13 CDK13 PWWP2A PWWP2A MED4 MED4 MED18 MED18 MED21 MED21 CDK9 CDK9 CBX7 CBX7 ELL2 ELL2 MED26 MED26 NCBP1 NCBP1 GTF2F1 GTF2F1 MED28 MED28 MED25 MED25
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDC73Cell division cycle 73. (531 aa)
MED29Mediator complex subunit 29. (201 aa)
MED23Mediator complex subunit 23. (1329 aa)
CCNKCyclin K; Belongs to the cyclin family. (571 aa)
ELL3Elongation factor for RNA polymerase II 3. (399 aa)
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (337 aa)
EAPPE2F associated phosphoprotein. (245 aa)
MED9Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (146 aa)
MED27Mediator complex subunit 27. (311 aa)
ENSMNEP00000019186Occludin_ELL domain-containing protein. (347 aa)
MED11Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (117 aa)
BTBD18BTB domain containing 18. (713 aa)
MED19Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (261 aa)
MED22Mediator complex subunit 22. (200 aa)
MED14Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1454 aa)
BRD4Bromodomain containing 4. (1337 aa)
MED30Mediator complex subunit 30. (178 aa)
MED24Uncharacterized protein. (1008 aa)
CDK12Cyclin dependent kinase 12. (1490 aa)
LOC105498354Uncharacterized protein. (998 aa)
MED7Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (232 aa)
TCERG1Transcription elongation regulator 1. (1096 aa)
CTNNB1Catenin beta 1. (781 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (760 aa)
SUPT16HSPT16 homolog, facilitates chromatin remodeling subunit. (1029 aa)
PWWP2BPWWP domain containing 2B. (590 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (728 aa)
MED16Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (841 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1713 aa)
ELLElongation factor for RNA polymerase II. (637 aa)
MED31Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa)
MED15Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (788 aa)
CDK13Cyclin dependent kinase 13. (1511 aa)
PWWP2APWWP domain containing 2A. (755 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (270 aa)
MED18Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (208 aa)
MED21Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (160 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
CBX7Chromobox 7. (251 aa)
ELL2Elongation factor for RNA polymerase II 2. (640 aa)
MED26TFIIS N-terminal domain-containing protein. (600 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (517 aa)
MED28Mediator complex subunit 28. (178 aa)
MED25Mediator complex subunit 25. (747 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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