STRINGSTRING
FKBP1B FKBP1B REEP5 REEP5 CAMK2D CAMK2D MRLN MRLN SRL SRL ITPR2 ITPR2 SLN SLN CASQ1 CASQ1 JSRP1 JSRP1 SRI SRI ASPH ASPH TMEM38B TMEM38B ATP2A2 ATP2A2 DHRS7C DHRS7C RYR3 RYR3 ENSMNEP00000019763 ENSMNEP00000019763 RTN2 RTN2 STRIT1 STRIT1 RYR1 RYR1 TRDN TRDN ART1 ART1 ENSMNEP00000024989 ENSMNEP00000024989 TMEM109 TMEM109 NOS1AP NOS1AP JPH3 JPH3 JPH4 JPH4 DMPK DMPK STIM1 STIM1 ATP2A1 ATP2A1 KLHL41 KLHL41 CAMK2B CAMK2B AKAP6 AKAP6 ENSMNEP00000034665 ENSMNEP00000034665 CAMK2G CAMK2G ATP2A3 ATP2A3 JPH1 JPH1 JPH2 JPH2 RYR2 RYR2 PLN PLN CHERP CHERP TMEM38A TMEM38A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FKBP1BPeptidylprolyl isomerase. (108 aa)
REEP5Receptor expression-enhancing protein. (193 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
MRLNMyoregulin. (46 aa)
SRLDynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1016 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
SLNUncharacterized protein. (31 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (399 aa)
JSRP1Junctional sarcoplasmic reticulum protein 1. (333 aa)
SRISorcin. (198 aa)
ASPHAspartate beta-hydroxylase. (762 aa)
TMEM38BTransmembrane protein 38B. (291 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
DHRS7CDehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (311 aa)
RYR3Ryanodine receptor 3. (4856 aa)
ENSMNEP00000019763Uncharacterized protein. (285 aa)
RTN2Reticulon. (545 aa)
STRIT1Small transmembrane regulator of ion transport 1. (35 aa)
RYR1Ryanodine receptor 1. (4913 aa)
TRDNTriadin. (725 aa)
ART1NAD(P)(+)--arginine ADP-ribosyltransferase. (361 aa)
ENSMNEP00000024989KASH domain-containing protein. (3507 aa)
TMEM109Transmembrane protein 109. (243 aa)
NOS1APPID domain-containing protein. (695 aa)
JPH3Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (748 aa)
JPH4Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (628 aa)
DMPKDM1 protein kinase. (630 aa)
STIM1Stromal interaction molecule 1. (790 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1030 aa)
KLHL41Kelch like family member 41. (544 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
AKAP6A-kinase anchoring protein 6. (2319 aa)
ENSMNEP00000034665Uncharacterized protein. (98 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (556 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1037 aa)
JPH1Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (661 aa)
JPH2Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (696 aa)
RYR2Ryanodine receptor 2. (4951 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
CHERPCalcium homeostasis endoplasmic reticulum protein. (927 aa)
TMEM38ATransmembrane protein 38A. (299 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.