16 items (Macaca nemestrina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FGB	Fibrinogen beta chain. (491 aa)
	LCK	Tyrosine-protein kinase. (540 aa)
	CD44	CD44 molecule (Indian blood group). (742 aa)
	SKAP1	Src kinase associated phosphoprotein 1. (359 aa)
	FGA	Fibrinogen alpha chain. (862 aa)
	BMP7	Bone morphogenetic protein 7. (431 aa)
	THY1	Thy-1 cell surface antigen. (161 aa)
	LOC105495285	Uncharacterized protein. (344 aa)
	GCNT2-2	Uncharacterized protein. (409 aa)
	GCNT2	Glucosaminyl (N-acetyl) transferase 2 (I blood group). (351 aa)
	FLOT1	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
	AGER	Advanced glycosylation end-product specific receptor. (414 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
	IL1B	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
	FGG	Fibrinogen gamma chain. (437 aa)
	ENSMNEP00000028413	Uncharacterized protein. (313 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGER	IL1B	ENSMNEP00000018479	ENSMNEP00000033521	Advanced glycosylation end-product specific receptor.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.421
CD44	LCK	ENSMNEP00000005624	ENSMNEP00000026636	CD44 molecule (Indian blood group).	Tyrosine-protein kinase.	0.485
CD44	THY1	ENSMNEP00000005624	ENSMNEP00000005372	CD44 molecule (Indian blood group).	Thy-1 cell surface antigen.	0.715
CD44	TNF	ENSMNEP00000005624	ENSMNEP00000029202	CD44 molecule (Indian blood group).	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.587
FGA	FGB	ENSMNEP00000021706	ENSMNEP00000025577	Fibrinogen alpha chain.	Fibrinogen beta chain.	0.999
FGA	FGG	ENSMNEP00000021706	ENSMNEP00000030951	Fibrinogen alpha chain.	Fibrinogen gamma chain.	0.999
FGB	FGA	ENSMNEP00000025577	ENSMNEP00000021706	Fibrinogen beta chain.	Fibrinogen alpha chain.	0.999
FGB	FGG	ENSMNEP00000025577	ENSMNEP00000030951	Fibrinogen beta chain.	Fibrinogen gamma chain.	0.999
FGG	FGA	ENSMNEP00000030951	ENSMNEP00000021706	Fibrinogen gamma chain.	Fibrinogen alpha chain.	0.999
FGG	FGB	ENSMNEP00000030951	ENSMNEP00000025577	Fibrinogen gamma chain.	Fibrinogen beta chain.	0.999
IL1B	AGER	ENSMNEP00000033521	ENSMNEP00000018479	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Advanced glycosylation end-product specific receptor.	0.421
IL1B	TNF	ENSMNEP00000033521	ENSMNEP00000029202	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.953
LCK	CD44	ENSMNEP00000026636	ENSMNEP00000005624	Tyrosine-protein kinase.	CD44 molecule (Indian blood group).	0.485
LCK	SKAP1	ENSMNEP00000026636	ENSMNEP00000003343	Tyrosine-protein kinase.	Src kinase associated phosphoprotein 1.	0.516
SKAP1	LCK	ENSMNEP00000003343	ENSMNEP00000026636	Src kinase associated phosphoprotein 1.	Tyrosine-protein kinase.	0.516
THY1	CD44	ENSMNEP00000005372	ENSMNEP00000005624	Thy-1 cell surface antigen.	CD44 molecule (Indian blood group).	0.715
TNF	CD44	ENSMNEP00000029202	ENSMNEP00000005624	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	CD44 molecule (Indian blood group).	0.587
TNF	IL1B	ENSMNEP00000029202	ENSMNEP00000033521	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.953