Your Input: | |
| | PCK2 | Phosphoenolpyruvate carboxykinase 2, mitochondrial. (645 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa) |
| | GPT | Glutamic--pyruvic transaminase. (496 aa) |
| | RNF152 | Ring finger protein 152. (203 aa) |
| | GAS2L1 | Growth arrest specific 2 like 1. (681 aa) |
| | NPRL3 | NPR3 like, GATOR1 complex subunit. (505 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | GALP | Galanin-like peptide; [Isoform 1]: Hypothalamic neuropeptide which binds to the G- protein-coupled galanin receptors (GALR1, GALR2 and GALR3). Involved in a large number of putative physiological functions in CNS homeostatic processes, including the regulation of gonadotropin-releasing hormone secretion (By similarity). (115 aa) |
| | LOC105468592 | Perilipin; Belongs to the perilipin family. (437 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (892 aa) |
| | FLCN | Folliculin. (579 aa) |
| | ENSMNEP00000003819 | Uncharacterized protein. (322 aa) |
| | GABARAPL2 | GABA type A receptor associated protein like 2. (117 aa) |
| | RRAGA | Ras related GTP binding A. (313 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1335 aa) |
| | SSTR3 | Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family. (418 aa) |
| | BHLHA15 | Basic helix-loop-helix family member a15. (191 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | COMT | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (221 aa) |
| | STK26 | Serine/threonine kinase 26. (428 aa) |
| | EIF2AK4 | Eukaryotic translation initiation factor 2 alpha kinase 4. (1649 aa) |
| | HSPA5 | Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa) |
| | DSC2 | Desmocollin 2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (901 aa) |
| | SLC34A1 | Solute carrier family 34 member 1. (639 aa) |
| | HFE | Homeostatic iron regulator; Belongs to the MHC class I family. (348 aa) |
| | BRSK1 | BR serine/threonine kinase 1. (734 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity). (331 aa) |
| | NIM1K | NIM1 serine/threonine protein kinase; Belongs to the protein kinase superfamily. (436 aa) |
| | NFE2L2 | Nuclear factor, erythroid 2 like 2. (618 aa) |
| | TBL2 | Transducin beta like 2. (446 aa) |
| | ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (704 aa) |
| | GLUL | Glutamine synthetase. (373 aa) |
| | PLIN3 | Perilipin; Belongs to the perilipin family. (438 aa) |
| | MFSD2A | Major facilitator superfamily domain containing 2A. (530 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (798 aa) |
| | SLC38A3 | Solute carrier family 38 member 3. (521 aa) |
| | ENSMNEP00000008701 | Uncharacterized protein. (126 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2546 aa) |
| | ENSMNEP00000010061 | Uncharacterized protein. (102 aa) |
| | KRT20 | Keratin 20; Belongs to the intermediate filament family. (424 aa) |
| | LRRK2 | Leucine rich repeat kinase 2. (2512 aa) |
| | MTMR3 | Myotubularin related protein 3. (1207 aa) |
| | RRP8 | Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (498 aa) |
| | GCN1 | GCN1 activator of EIF2AK4. (2671 aa) |
| | FOXK1 | Forkhead box K1. (715 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) |
| | BCAS3 | BCAS3 microtubule associated cell migration factor. (922 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa) |
| | SESN3 | Sestrin 3. (492 aa) |
| | INHBB | Inhibin subunit beta B. (407 aa) |
| | ENSMNEP00000012226 | Uncharacterized protein. (104 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | ULK2 | Unc-51 like autophagy activating kinase 2. (1035 aa) |
| | TTC5 | Tetratricopeptide repeat domain 5. (440 aa) |
| | UPP1 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (314 aa) |
| | SLC39A5 | Solute carrier family 39 member 5. (423 aa) |
| | BECN1 | Beclin 1. (450 aa) |
| | LOC105476784 | Uncharacterized protein. (147 aa) |
| | FOXO1 | Forkhead box O1. (655 aa) |
| | MAX | MYC associated factor X. (160 aa) |
| | ATG14 | Autophagy related 14. (493 aa) |
| | CBL | Cbl proto-oncogene. (907 aa) |
| | RIPOR1 | RHO family interacting cell polarization regulator 1. (1217 aa) |
| | C12orf66 | Chromosome 12 open reading frame 66. (504 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | RRAGB | Ras related GTP binding B. (349 aa) |
| | ENSMNEP00000016623 | Uncharacterized protein. (111 aa) |
| | PRKAG1 | Protein kinase AMP-activated non-catalytic subunit gamma 1. (331 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa) |
| | WRN | WRN RecQ like helicase. (1432 aa) |
| | MYBBP1A | MYB binding protein 1a. (1328 aa) |
| | LRP11 | LDL receptor related protein 11. (500 aa) |
| | KLF10 | Kruppel like factor 10. (480 aa) |
| | SESN1 | Sestrin 1. (551 aa) |
| | KIAA1324 | KIAA1324. (993 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) |
| | ENSMNEP00000018005 | Uncharacterized protein. (133 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2 alpha kinase 3. (1115 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) |
| | WDR24 | WD repeat domain 24. (902 aa) |
| | VPS41 | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa) |
| | XPR1 | Xenotropic and polytropic retrovirus receptor 1. (696 aa) |
| | PPM1D | Protein phosphatase, Mg2+/Mn2+ dependent 1D. (605 aa) |
| | MAP1LC3A | Microtubule associated protein 1 light chain 3 alpha. (125 aa) |
| | SREBF1 | Sterol regulatory element binding transcription factor 1. (1177 aa) |
| | PAGE1 | PAGE family member 1. (143 aa) |
| | SIK1 | Uncharacterized protein. (785 aa) |
| | RRAGD | Ras related GTP binding D. (400 aa) |
| | RNF167 | Ring finger protein 167. (350 aa) |
| | DAPL1 | Uncharacterized protein. (123 aa) |
| | XBP1 | BZIP domain-containing protein. (380 aa) |
| | ENSMNEP00000021069 | ZIP4_domain domain-containing protein. (585 aa) |
| | ULK1 | Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1049 aa) |
| | LAMP2 | Lysosomal associated membrane protein 2. (411 aa) |
| | CBWD1 | CobW C-terminal domain-containing protein. (395 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (467 aa) |
| | PRAF2 | Uncharacterized protein. (361 aa) |
| | SIRT1 | Sirtuin 1. (743 aa) |
| | EIF2A | Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (576 aa) |
| | CPEB4 | Cytoplasmic polyadenylation element binding protein 4. (729 aa) |
| | LOC105493965 | GAGE domain-containing protein. (68 aa) |
| | MAP1LC3B | Uncharacterized protein. (125 aa) |
| | WIPI2 | WD repeat domain, phosphoinositide interacting 2. (451 aa) |
| | KPTN | Kaptin, actin binding protein. (435 aa) |
| | AOC1 | Amine oxidase. (755 aa) |
| | SLC2A1 | Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (506 aa) |
| | ENSMNEP00000023592 | RWD domain-containing protein. (306 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (891 aa) |
| | CPS1 | Carbamoyl-phosphate synthase 1. (1500 aa) |
| | GNPAT | Dihydroxyacetone phosphate acyltransferase. (684 aa) |
| | NUAK2 | NUAK family kinase 2. (672 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa) |
| | MIOS | Meiosis regulator for oocyte development. (875 aa) |
| | PCSK9 | Proprotein convertase subtilisin/kexin type 9; Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway. May prevent the recycling of LDLR from endosomes to [...] (811 aa) |
| | EHMT2 | Euchromatic histone lysine methyltransferase 2. (1266 aa) |
| | TFEB | Transcription factor EB. (490 aa) |
| | FOXK2 | Forkhead box K2. (658 aa) |
| | RRAGC | Ras related GTP binding C. (399 aa) |
| | HCRT | Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family. (131 aa) |
| | GAS6 | Growth arrest specific 6. (683 aa) |
| | NUAK1 | NUAK family kinase 1. (667 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (314 aa) |
| | HMGCS2 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa) |
| | WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa) |
| | PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa) |
| | PIK3R4 | Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa) |
| | ATF4 | Activating transcription factor 4. (351 aa) |
| | SSTR2 | Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family. (402 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | CLEC16A | C-type lectin domain containing 16A. (1053 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (568 aa) |
| | IFI16 | Interferon gamma inducible protein 16. (729 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) |
| | DNAJC15 | DnaJ heat shock protein family (Hsp40) member C15. (150 aa) |
| | LARP1 | La ribonucleoprotein domain family member 1. (978 aa) |
| | ENSMNEP00000032267 | GAGE domain-containing protein. (100 aa) |
| | PFKFB1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (471 aa) |
| | ITFG2 | Integrin alpha FG-GAP repeat containing 2. (447 aa) |
| | TBC1D5 | TBC1 domain family member 5. (821 aa) |
| | ZFP36 | ZFP36 ring finger protein. (332 aa) |
| | EIF2AK2 | Eukaryotic translation initiation factor 2 alpha kinase 2. (488 aa) |
| | SESN2 | Sestrin 2. (480 aa) |
| | WDR45B | WD repeat domain 45B. (298 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (601 aa) |
| | FOXA3 | Forkhead box A3. (351 aa) |
| | BMT2 | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (405 aa) |
| | SREBF2 | Sterol regulatory element binding transcription factor 2. (1248 aa) |
| | AMBRA1 | Autophagy and beclin 1 regulator 1. (1298 aa) |
| | CARTPT | CART prepropeptide. (116 aa) |
| | FBXO22 | F-box protein 22. (404 aa) |
| | SZT2 | SZT2 subunit of KICSTOR complex. (3432 aa) |
| | CHKA | Choline kinase alpha. (453 aa) |
| | ADM | Adrenomedullin. (185 aa) |
| | WIPI1 | WD repeat domain, phosphoinositide interacting 1. (462 aa) |
| | GIP | Gastric inhibitory polypeptide. (153 aa) |
| | MYH13 | Myosin heavy chain 13; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1903 aa) |
| | PDK4 | Protein-serine/threonine kinase. (411 aa) |
| | ENSMNEP00000038888 | GAGE domain-containing protein. (78 aa) |
| | NPRL2 | NPR2 like, GATOR1 complex subunit. (380 aa) |
| | PICK1 | Protein interacting with PRKCA 1. (414 aa) |
| | SEH1L | SEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (429 aa) |
| | JMY | Junction mediating and regulatory protein, p53 cofactor. (990 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1374 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (489 aa) |
| | ENSMNEP00000041082 | Uncharacterized protein; Belongs to the heat shock protein 70 family. (558 aa) |
| | SLC7A5 | Solute carrier family 7 member 5. (507 aa) |
| | MYOD1 | Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa) |
| | STK24 | Serine/threonine kinase 24. (443 aa) |
| | FNIP1 | Folliculin interacting protein 1. (1166 aa) |
| | DAP | Uncharacterized protein. (102 aa) |
| | ENSMNEP00000043437 | WD_REPEATS_REGION domain-containing protein. (500 aa) |
| | PIK3C2B | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1634 aa) |
| | ALB | Albumin. (608 aa) |
| | ATF3 | Activating transcription factor 3. (181 aa) |
| | BRSK2 | BR serine/threonine kinase 2. (759 aa) |
| | GCGR | Glucagon receptor; Belongs to the G-protein coupled receptor 2 family. (491 aa) |
| | IMPACT | RWD domain-containing protein. (320 aa) |
