STRINGSTRING
PSEN1 PSEN1 BACE1 BACE1 ADAM19 ADAM19 NCSTN NCSTN ADAM10 ADAM10 PSENEN PSENEN CLN3 CLN3 PSEN2 PSEN2 ABCA7 ABCA7 APH1B APH1B APH1A APH1A LOC105493395 LOC105493395 ADAM17 ADAM17 ABCG1 ABCG1 DYRK1A DYRK1A ADAM9 ADAM9 LOC105493392 LOC105493392
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
BACE1Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa)
ADAM19ADAM metallopeptidase domain 19. (918 aa)
NCSTNNicastrin. (721 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
CLN3Battenin. (438 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa)
ABCA7ATP binding cassette subfamily A member 7. (2128 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
LOC105493395Uncharacterized protein. (905 aa)
ADAM17ADAM metallopeptidase domain 17. (803 aa)
ABCG1ATP binding cassette subfamily G member 1. (690 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (763 aa)
ADAM9ADAM metallopeptidase domain 9. (816 aa)
LOC105493392Uncharacterized protein. (825 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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