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CCN3 CCN3 PTEN PTEN MYH9 MYH9 ABL1 ABL1 ROBO1 ROBO1 HMGB1 HMGB1 RAB13 RAB13 ENSMNEP00000010344 ENSMNEP00000010344 EPHB4 EPHB4 PAXIP1 PAXIP1 NR4A1 NR4A1 ITGB2 ITGB2 MIA3 MIA3 FAP FAP EMP2 EMP2 TGFBR1 TGFBR1 MMRN2 MMRN2 VSTM4 VSTM4 GIPC2 GIPC2 ADGRA2 ADGRA2 PTK2B PTK2B GIPC3 GIPC3 PIK3CA PIK3CA SOX18 SOX18 SNAI2 SNAI2 TNFSF12 TNFSF12 GIPC1 GIPC1 CORO1B CORO1B PLEKHG5 PLEKHG5 SLIT2 SLIT2 TDGF1 TDGF1 KDR KDR CDH5 CDH5 ENSMNEP00000039545 ENSMNEP00000039545 CCBE1 CCBE1 PIK3R3 PIK3R3 RHOA RHOA PTP4A3 PTP4A3 CALCA CALCA S100P S100P LOXL2 LOXL2 SRF SRF LGALS12 LGALS12 S100A2 S100A2 FSTL1 FSTL1 ID1 ID1 ADTRP ADTRP PXN PXN NRP1 NRP1 EFNB2 EFNB2 SCARB1 SCARB1 EDN2 EDN2 CYP1B1 CYP1B1 LPXN LPXN DPP4 DPP4 AKT1 AKT1 AMOT AMOT ENSMNEP00000025766 ENSMNEP00000025766 PLXND1 PLXND1 EGR3 EGR3 GPLD1 GPLD1 CXCL13 CXCL13 LGALS8 LGALS8 STARD13 STARD13 NOS3 NOS3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCN3Cellular communication network factor 3. (376 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
ROBO1Roundabout guidance receptor 1. (1539 aa)
HMGB1High mobility group box 1. (215 aa)
RAB13Uncharacterized protein. (203 aa)
ENSMNEP00000010344Uncharacterized protein. (206 aa)
EPHB4EPH receptor B4. (987 aa)
PAXIP1PAX interacting protein 1. (1069 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (652 aa)
ITGB2Integrin beta. (921 aa)
MIA3MIA SH3 domain ER export factor 3. (1907 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
MMRN2Multimerin 2. (953 aa)
VSTM4V-set and transmembrane domain containing 4. (321 aa)
GIPC2GIPC PDZ domain containing family member 2. (319 aa)
ADGRA2Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1340 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
GIPC3GIPC PDZ domain containing family member 3. (312 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SOX18SRY-box transcription factor 18. (354 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
TNFSF12TNF superfamily member 12; Belongs to the tumor necrosis factor family. (249 aa)
GIPC1GIPC PDZ domain containing family member 1. (333 aa)
CORO1BCoronin; Belongs to the WD repeat coronin family. (489 aa)
PLEKHG5Pleckstrin homology and RhoGEF domain containing G5. (1066 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
TDGF1Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (187 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
ENSMNEP00000039545Uncharacterized protein. (196 aa)
CCBE1Collagen and calcium binding EGF domains 1. (406 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (463 aa)
RHOARas homolog family member A. (193 aa)
PTP4A3Protein tyrosine phosphatase 4A3. (173 aa)
CALCACalcitonin related polypeptide alpha. (140 aa)
S100PS100 calcium binding protein P. (95 aa)
LOXL2Lysyl oxidase like 2. (774 aa)
SRFSerum response factor. (508 aa)
LGALS12Galectin. (327 aa)
S100A2Protein S100; Belongs to the S-100 family. (98 aa)
FSTL1Follistatin like 1. (319 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (154 aa)
ADTRPAndrogen dependent TFPI regulating protein. (248 aa)
PXNPaxillin. (1082 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (925 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (336 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (553 aa)
EDN2Endothelin 2. (206 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (542 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (766 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
AMOTAngiomotin. (1101 aa)
ENSMNEP00000025766CFC domain-containing protein. (170 aa)
PLXND1Plexin D1. (1925 aa)
EGR3Early growth response 3. (387 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (847 aa)
CXCL13C-X-C motif chemokine. (109 aa)
LGALS8Galectin. (358 aa)
STARD13StAR related lipid transfer domain containing 13. (1113 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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