30 items (Macaca nemestrina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VAV2	Vav guanine nucleotide exchange factor 2. (878 aa)
	CCL19	C-C motif chemokine. (123 aa)
	CCL21	C-C motif chemokine ligand 21. (131 aa)
	AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1192 aa)
	FGR	Tyrosine-protein kinase. (529 aa)
	FGFR3	Fibroblast growth factor receptor. (808 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
	IRS1	Insulin receptor substrate 1. (1241 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	ERBB4	Receptor protein-tyrosine kinase. (1308 aa)
	AMBRA1	Autophagy and beclin 1 regulator 1. (1298 aa)
	PDGFB	Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
	PIK3R4	Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa)
	TEK	TEK receptor tyrosine kinase. (1124 aa)
	PTK2	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1054 aa)
	CD19	CD19 molecule. (583 aa)
	PDGFRB	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
	KIT	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
	PTK2B	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
	ENSMNEP00000017998	Protein kinase domain-containing protein. (356 aa)
	NOD2	Nucleotide binding oligomerization domain containing 2. (1044 aa)
	FLT3	Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (995 aa)
	FLT1	Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
	ATG14	Autophagy related 14. (493 aa)
	CCR7	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (875 aa)
	SRC	Tyrosine-protein kinase. (644 aa)
	EPHA8	EPH receptor A8. (999 aa)
	PRKD1	Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (892 aa)
	TNFAIP8L3	TNF alpha induced protein 8 like 3. (292 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMBRA1	ATG14	ENSMNEP00000036577	ENSMNEP00000014955	Autophagy and beclin 1 regulator 1.	Autophagy related 14.	0.975
AMBRA1	PIK3R4	ENSMNEP00000036577	ENSMNEP00000028123	Autophagy and beclin 1 regulator 1.	Phosphoinositide-3-kinase regulatory subunit 4.	0.955
ATG14	AMBRA1	ENSMNEP00000014955	ENSMNEP00000036577	Autophagy related 14.	Autophagy and beclin 1 regulator 1.	0.975
ATG14	PIK3R4	ENSMNEP00000014955	ENSMNEP00000028123	Autophagy related 14.	Phosphoinositide-3-kinase regulatory subunit 4.	0.998
CCL19	CCL21	ENSMNEP00000046138	ENSMNEP00000043476	C-C motif chemokine.	C-C motif chemokine ligand 21.	0.995
CCL19	CCR7	ENSMNEP00000046138	ENSMNEP00000012848	C-C motif chemokine.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.999
CCL21	CCL19	ENSMNEP00000043476	ENSMNEP00000046138	C-C motif chemokine ligand 21.	C-C motif chemokine.	0.995
CCL21	CCR7	ENSMNEP00000043476	ENSMNEP00000012848	C-C motif chemokine ligand 21.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.996
CCR7	CCL19	ENSMNEP00000012848	ENSMNEP00000046138	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine.	0.999
CCR7	CCL21	ENSMNEP00000012848	ENSMNEP00000043476	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine ligand 21.	0.996
CCR7	CD19	ENSMNEP00000012848	ENSMNEP00000022968	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	CD19 molecule.	0.778
CD19	CCR7	ENSMNEP00000022968	ENSMNEP00000012848	CD19 molecule.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.778
CD19	LYN	ENSMNEP00000022968	ENSMNEP00000037491	CD19 molecule.	Tyrosine-protein kinase.	0.964
CD19	SRC	ENSMNEP00000022968	ENSMNEP00000006319	CD19 molecule.	Tyrosine-protein kinase.	0.491
CD19	VAV2	ENSMNEP00000022968	ENSMNEP00000024197	CD19 molecule.	Vav guanine nucleotide exchange factor 2.	0.946
CD19	VAV3	ENSMNEP00000022968	ENSMNEP00000009315	CD19 molecule.	Vav guanine nucleotide exchange factor 3.	0.946
ENSMNEP00000017998	PDGFB	ENSMNEP00000017998	ENSMNEP00000029459	Protein kinase domain-containing protein.	Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.	0.756
ENSMNEP00000017998	PDGFRB	ENSMNEP00000017998	ENSMNEP00000019066	Protein kinase domain-containing protein.	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.	0.627
ENSMNEP00000017998	PTK2	ENSMNEP00000017998	ENSMNEP00000024613	Protein kinase domain-containing protein.	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.583
ENSMNEP00000017998	PTK2B	ENSMNEP00000017998	ENSMNEP00000018352	Protein kinase domain-containing protein.	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.437