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CLIC1 CLIC1 LRP5 LRP5 PDLIM7 PDLIM7 IL6R IL6R CCN1 CCN1 DDR2 DDR2 LOC105470579 LOC105470579 IL6 IL6 CTNNB1 CTNNB1 IGF1 IGF1 BMP7 BMP7 CEBPB CEBPB SOX11 SOX11 PRKD1 PRKD1 GLI3 GLI3 WNT10B WNT10B SCUBE3 SCUBE3 NELL1 NELL1 LRP3 LRP3 SMAD1 SMAD1 FBN2 FBN2 WWTR1 WWTR1 TENT5A TENT5A WNT4 WNT4 ENSMNEP00000010426 ENSMNEP00000010426 WNT7B WNT7B TP63 TP63 FFAR4 FFAR4 YAP1 YAP1 NPPC NPPC BMPR2 BMPR2 GDPD2 GDPD2 BMPR1A BMPR1A ACVR2B ACVR2B CTNNBIP1 CTNNBIP1 FERMT2 FERMT2 IL6ST IL6ST BMP6 BMP6 MEF2C MEF2C FBXO5 FBXO5 BMP4 BMP4 BMP2 BMP2 SCUBE2 SCUBE2 PPP3CA PPP3CA GDF10 GDF10 ACVR1 ACVR1 LTF LTF FAM20C FAM20C CEBPD CEBPD TMEM119 TMEM119 JAG1 JAG1 CTHRC1 CTHRC1 WDR63 WDR63 SFRP2 SFRP2 SUCO SUCO ATRAID ATRAID CCN4 CCN4 HGF HGF BMPR1B BMPR1B ZHX3 ZHX3 SMAD5 SMAD5 RUNX2 RUNX2 ENSMNEP00000039881 ENSMNEP00000039881 ACVR2A ACVR2A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLIC1Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (241 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1599 aa)
PDLIM7PDZ and LIM domain 7. (457 aa)
IL6RInterleukin 6 receptor. (467 aa)
CCN1Cellular communication network factor 1. (381 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (873 aa)
LOC105470579Uncharacterized protein. (245 aa)
IL6Interleukin 6. (214 aa)
CTNNB1Catenin beta 1. (781 aa)
IGF1Insulin like growth factor 1. (208 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
CEBPBCCAAT/enhancer-binding protein. (344 aa)
SOX11Transcription factor SOX. (441 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (892 aa)
GLI3GLI family zinc finger 3. (1580 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
SCUBE3Signal peptide, CUB domain and EGF like domain containing 3. (993 aa)
NELL1Neural EGFL like 1. (838 aa)
LRP3LDL receptor related protein 3. (770 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
FBN2Fibrillin 2. (2912 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
TENT5ATerminal nucleotidyltransferase 5A. (465 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
ENSMNEP00000010426Uncharacterized protein. (225 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (686 aa)
FFAR4Free fatty acid receptor 4. (377 aa)
YAP1Yes associated protein 1. (506 aa)
NPPCNatriuretic peptide C. (126 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
GDPD2Glycerophosphodiester phosphodiesterase domain containing 2. (590 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
FERMT2Fermitin family member 2. (689 aa)
IL6STInterleukin 6 signal transducer. (942 aa)
BMP6Bone morphogenetic protein 6. (513 aa)
MEF2CMyocyte enhancer factor 2C. (486 aa)
FBXO5F-box protein 5. (401 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (996 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (477 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
LTFLactotransferrin; Belongs to the transferrin family. (747 aa)
FAM20CFAM20C golgi associated secretory pathway kinase. (584 aa)
CEBPDCCAAT/enhancer-binding protein. (269 aa)
TMEM119Transmembrane protein 119. (280 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
CTHRC1Collagen triple helix repeat containing 1. (243 aa)
WDR63WD repeat domain 63. (861 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
SUCOSUN domain containing ossification factor. (1384 aa)
ATRAIDAll-trans retinoic acid induced differentiation factor. (284 aa)
CCN4Cellular communication network factor 4. (367 aa)
HGFHepatocyte growth factor; Belongs to the peptidase S1 family. (788 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ZHX3Zinc fingers and homeoboxes 3. (969 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
RUNX2RUNX family transcription factor 2. (542 aa)
ENSMNEP00000039881Uncharacterized protein. (210 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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