STRINGSTRING
GPR68 GPR68 LOC105470579 LOC105470579 IL20 IL20 NINJ1 NINJ1 NOTCH2 NOTCH2 CREB1 CREB1 ENSMNEP00000012002 ENSMNEP00000012002 FOS FOS TNFSF11 TNFSF11 KLF10 KLF10 PPARGC1B PPARGC1B IL23A IL23A OCSTAMP OCSTAMP POU4F2 POU4F2 TREM2 TREM2 PPP3CA PPP3CA CSF1 CSF1 TNF TNF NEDD9 NEDD9 TMEM64 TMEM64 POU4F1 POU4F1 IL17A IL17A IL23R IL23R TRAF6 TRAF6 SLC9B2 SLC9B2 IFNG IFNG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GPR68G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (375 aa)
LOC105470579Uncharacterized protein. (245 aa)
IL20Interleukin 20. (176 aa)
NINJ1Ninjurin 1. (152 aa)
NOTCH2Notch receptor 2. (2471 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
ENSMNEP00000012002TNF receptor-associated factor. (457 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
KLF10Kruppel like factor 10. (480 aa)
PPARGC1BPPARG coactivator 1 beta. (1023 aa)
IL23AInterleukin 23 subunit alpha. (189 aa)
OCSTAMPOsteoclast stimulatory transmembrane protein. (555 aa)
POU4F2POU domain protein. (408 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (555 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (839 aa)
TMEM64Transmembrane protein 64. (381 aa)
POU4F1POU domain protein. (380 aa)
IL17AInterleukin 17A. (155 aa)
IL23RInterleukin 23 receptor. (576 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
SLC9B2Solute carrier family 9 member B2. (522 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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