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PLN | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa) | ||||
SPTBN4 | Spectrin beta chain; Belongs to the spectrin family. (2543 aa) | ||||
GJD3 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (294 aa) | ||||
GRK2 | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa) | ||||
PDE5A | Phosphodiesterase. (875 aa) | ||||
SPX | Spexin hormone. (116 aa) | ||||
BIN1 | Bridging integrator 1. (608 aa) | ||||
AGTR2 | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa) | ||||
TRPV1 | Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (748 aa) | ||||
PDE4D | Phosphodiesterase. (809 aa) | ||||
SRI | Sorcin. (198 aa) | ||||
ATP2A2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa) | ||||
ADRA1A | Adrenoceptor alpha 1A. (466 aa) | ||||
RNLS | Renalase, FAD dependent amine oxidase. (342 aa) | ||||
ATP1A1 | Sodium/potassium-transporting ATPase subunit alpha. (1027 aa) | ||||
ATP1A2 | Sodium/potassium-transporting ATPase subunit alpha. (1023 aa) | ||||
ZC3H12A | Zinc finger CCCH-type containing 12A. (601 aa) | ||||
ENSMNEP00000034665 | Uncharacterized protein. (98 aa) | ||||
PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) | ||||
FKBP1B | Peptidylprolyl isomerase. (108 aa) |