STRINGSTRING
STAU1 STAU1 DLG4 DLG4 SHANK3 SHANK3 P2RX3 P2RX3 ENSMNEP00000000829 ENSMNEP00000000829 LRRTM1 LRRTM1 RAPGEF2 RAPGEF2 CYP46A1 CYP46A1 HRH1 HRH1 SCT SCT ENSMNEP00000002319 ENSMNEP00000002319 MAP1A MAP1A DGKI DGKI SERPINE2 SERPINE2 GRID2 GRID2 PTN PTN DRD5 DRD5 MECP2 MECP2 CPLX2 CPLX2 MPP6 MPP6 KCNB1 KCNB1 CRTC1 CRTC1 NEUROD2 NEUROD2 EIF2AK4 EIF2AK4 FMR1 FMR1 BRAF BRAF GSK3B GSK3B CDC20 CDC20 PLK2 PLK2 SHISA7 SHISA7 PTEN PTEN ANAPC2 ANAPC2 BRSK1 BRSK1 ABL1 ABL1 PAIP2 PAIP2 GFAP GFAP ADCY1 ADCY1 NETO1 NETO1 NSMF NSMF NPTN NPTN GRIN2C GRIN2C RASGRF2 RASGRF2 RARA RARA NF1 NF1 SLC1A1 SLC1A1 NTRK2 NTRK2 CALB1 CALB1 DBN1 DBN1 MAP1B MAP1B MAPK1 MAPK1 GRIK2 GRIK2 NPAS4 NPAS4 NFATC4 NFATC4 RIMS2 RIMS2 ITPKA ITPKA YTHDF1 YTHDF1 GRIN2B GRIN2B ACE ACE ARC ARC STX4 STX4 CX3CR1 CX3CR1 SHANK2 SHANK2 LRRTM2 LRRTM2 SLC24A2 SLC24A2 GRIN1 GRIN1 RAB3GAP1 RAB3GAP1 ENSMNEP00000016378 ENSMNEP00000016378 ERC1 ERC1 RIMS1 RIMS1 SLC8A2 SLC8A2 EIF4EBP2 EIF4EBP2 SHISA8 SHISA8 GIPC2 GIPC2 PPP3CB PPP3CB APOE APOE TSHZ3 TSHZ3 PTK2B PTK2B ADORA2A ADORA2A KIT KIT AGER AGER GIPC3 GIPC3 SYP SYP CX3CL1 CX3CL1 NRGN NRGN EPHA4 EPHA4 PTGS2 PTGS2 ENSMNEP00000020320 ENSMNEP00000020320 ERC2 ERC2 GRM5 GRM5 SLC4A10 SLC4A10 NR2E1 NR2E1 S100B S100B RIMS3 RIMS3 MPP2 MPP2 KAT2A KAT2A STAU2 STAU2 MCTP1 MCTP1 ZDHHC2 ZDHHC2 PENK PENK IGSF11 IGSF11 SYT12 SYT12 MEF2C MEF2C NCDN NCDN CNTN2 CNTN2 JPH3 JPH3 GRID2IP GRID2IP ITPR3 ITPR3 JPH4 JPH4 ADGRB1 ADGRB1 CLN3 CLN3 SYT4 SYT4 SYNPR SYNPR ACP4 ACP4 ARF1 ARF1 NEURL1 NEURL1 PSEN1 PSEN1 ATF4 ATF4 SORCS3 SORCS3 ABHD6 ABHD6 ZZEF1 ZZEF1 VGF VGF PRKCZ PRKCZ NOG NOG ENSMNEP00000029705 ENSMNEP00000029705 SYNGAP1 SYNGAP1 GRIN2A GRIN2A SYAP1 SYAP1 CALB2 CALB2 RELN RELN SIPA1L1 SIPA1L1 CBLN1 CBLN1 HRAS HRAS STX3 STX3 CAMK2B CAMK2B CHRDL1 CHRDL1 PRRT2 PRRT2 LGMN LGMN YWHAH YWHAH SNAP25 SNAP25 RGS14 RGS14 ADCY8 ADCY8 CRHR2 CRHR2 GRIA1 GRIA1 SCGN SCGN SLC8A3 SLC8A3 SLC24A1 SLC24A1 SRF SRF BAIAP2 BAIAP2 EPHB2 EPHB2 DRD2 DRD2 SORCS2 SORCS2 EGR2 EGR2 GIP GIP PICK1 PICK1 NSG1 NSG1 PRRT1 PRRT1 NCSTN NCSTN SNAP47 SNAP47 SHISA9 SHISA9 SYNGR1 SYNGR1 GRIN2D GRIN2D ENSMNEP00000042829 ENSMNEP00000042829 MME MME CNTN4 CNTN4 PPFIA3 PPFIA3 LZTS1 LZTS1 RASGRF1 RASGRF1 CDK5 CDK5 SCTR SCTR ENSMNEP00000044158 ENSMNEP00000044158 GIPC1 GIPC1 TNR TNR SYT7 SYT7 KRAS KRAS APP APP CPEB3 CPEB3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STAU1Staufen double-stranded RNA binding protein 1. (577 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (767 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1663 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
ENSMNEP00000000829Uncharacterized protein. (278 aa)
LRRTM1Leucine rich repeat transmembrane neuronal 1. (522 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1701 aa)
CYP46A1Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (500 aa)
HRH1Histamine receptor H1; Belongs to the G-protein coupled receptor 1 family. (487 aa)
SCTSecretin. (117 aa)
ENSMNEP00000002319Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (226 aa)
MAP1AMicrotubule associated protein 1A. (3042 aa)
DGKIDiacylglycerol kinase. (1079 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (409 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (1007 aa)
PTNPleiotrophin. (172 aa)
DRD5Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (478 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
CPLX2Complexin 2. (134 aa)
MPP6Membrane palmitoylated protein 6; Belongs to the MAGUK family. (582 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
CRTC1CREB regulated transcription coactivator 1. (650 aa)
NEUROD2Neurogenic differentiation factor. (382 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1649 aa)
FMR1Fragile X mental retardation 1. (632 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (763 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa)
CDC20Cell division cycle 20. (499 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
SHISA7Shisa family member 7. (538 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (822 aa)
BRSK1BR serine/threonine kinase 1. (734 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
PAIP2Poly(A) binding protein interacting protein 2. (124 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (517 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1088 aa)
NETO1Neuropilin and tolloid like 1. (533 aa)
NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor. (538 aa)
NPTNNeuroplastin. (398 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1242 aa)
RASGRF2Ras protein specific guanine nucleotide releasing factor 2. (1237 aa)
RARARetinoic acid receptor alpha. (477 aa)
NF1Neurofibromin 1. (2839 aa)
SLC1A1Solute carrier family 1 member 1. (524 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
CALB1Calbindin 1. (261 aa)
DBN1Drebrin 1. (695 aa)
MAP1BMicrotubule associated protein 1B. (2584 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (908 aa)
NPAS4Neuronal PAS domain protein 4. (802 aa)
NFATC4Nuclear factor of activated T cells 4. (961 aa)
RIMS2Regulating synaptic membrane exocytosis 2. (1367 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (461 aa)
YTHDF1YTH N6-methyladenosine RNA binding protein 1. (559 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
ACEAngiotensin-converting enzyme. (1160 aa)
ARCActivity regulated cytoskeleton associated protein. (471 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (297 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (386 aa)
SHANK2SH3 and multiple ankyrin repeat domains 2. (1849 aa)
LRRTM2Leucine rich repeat transmembrane neuronal 2. (516 aa)
SLC24A2Solute carrier family 24 member 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (664 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (996 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (989 aa)
ENSMNEP00000016378Protein kinase domain-containing protein. (652 aa)
ERC1ELKS/RAB6-interacting/CAST family member 1. (1080 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1691 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
EIF4EBP2Eukaryotic translation initiation factor 4E binding protein 2. (120 aa)
SHISA8Shisa family member 8. (398 aa)
GIPC2GIPC PDZ domain containing family member 2. (319 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
APOEApolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa)
TSHZ3Teashirt zinc finger homeobox 3. (1081 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
AGERAdvanced glycosylation end-product specific receptor. (414 aa)
GIPC3GIPC PDZ domain containing family member 3. (312 aa)
SYPSynaptophysin. (313 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (407 aa)
NRGNNeurogranin. (78 aa)
EPHA4EPH receptor A4. (997 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
ENSMNEP00000020320Uncharacterized protein. (109 aa)
ERC2ELKS/RAB6-interacting/CAST family member 2. (910 aa)
GRM5Glutamate metabotropic receptor 5. (1212 aa)
SLC4A10Anion exchange protein. (1175 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
S100BS_100 domain-containing protein; Belongs to the S-100 family. (94 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (308 aa)
MPP2Membrane palmitoylated protein 2; Belongs to the MAGUK family. (594 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
STAU2Staufen double-stranded RNA binding protein 2. (538 aa)
MCTP1Multiple C2 and transmembrane domain containing 1. (998 aa)
ZDHHC2Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (367 aa)
PENKProenkephalin. (267 aa)
IGSF11Immunoglobulin superfamily member 11. (431 aa)
SYT12Synaptotagmin 12. (421 aa)
MEF2CMyocyte enhancer factor 2C. (486 aa)
NCDNNeurochondrin. (729 aa)
CNTN2Contactin 2. (1040 aa)
JPH3Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (748 aa)
GRID2IPGrid2 interacting protein. (1211 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
JPH4Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (628 aa)
ADGRB1Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1566 aa)
CLN3Battenin. (438 aa)
SYT4Synaptotagmin 4. (425 aa)
SYNPRSynaptoporin. (285 aa)
ACP4Acid phosphatase 4; Belongs to the histidine acid phosphatase family. (428 aa)
ARF1ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (574 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
ATF4Activating transcription factor 4. (351 aa)
SORCS3Sortilin related VPS10 domain containing receptor 3. (1239 aa)
ABHD6Abhydrolase domain containing 6. (337 aa)
ZZEF1Zinc finger ZZ-type and EF-hand domain containing 1. (2962 aa)
VGFVGF nerve growth factor inducible. (595 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
ENSMNEP00000029705Uncharacterized protein. (336 aa)
SYNGAP1Synaptic Ras GTPase activating protein 1. (1328 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
SYAP1Synapse associated protein 1. (352 aa)
CALB2Calbindin 2. (271 aa)
RELNReelin. (3460 aa)
SIPA1L1Signal induced proliferation associated 1 like 1. (1804 aa)
CBLN1Cerebellin 1 precursor. (193 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (290 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
CHRDL1Chordin like 1. (458 aa)
PRRT2Proline rich transmembrane protein 2. (340 aa)
LGMNLegumain. (433 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
RGS14Regulator of G protein signaling 14. (583 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (431 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (893 aa)
SCGNSecretagogin, EF-hand calcium binding protein. (276 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (928 aa)
SLC24A1Solute carrier family 24 member 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (1075 aa)
SRFSerum response factor. (508 aa)
BAIAP2BAI1 associated protein 2. (552 aa)
EPHB2EPH receptor B2. (1063 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
SORCS2Sortilin related VPS10 domain containing receptor 2. (1162 aa)
EGR2Early growth response 2. (426 aa)
GIPGastric inhibitory polypeptide. (153 aa)
PICK1Protein interacting with PRKCA 1. (414 aa)
NSG1Neuronal vesicle trafficking associated 1. (185 aa)
PRRT1Proline rich transmembrane protein 1. (306 aa)
NCSTNNicastrin. (721 aa)
SNAP47Synaptosome associated protein 47. (419 aa)
SHISA9Shisa family member 9. (424 aa)
SYNGR1Synaptogyrin. (230 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (1299 aa)
ENSMNEP00000042829Uncharacterized protein. (204 aa)
MMEMembrane metalloendopeptidase. (750 aa)
CNTN4Contactin 4. (1010 aa)
PPFIA3PTPRF interacting protein alpha 3. (1220 aa)
LZTS1Leucine zipper tumor suppressor 1. (596 aa)
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1273 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
SCTRSecretin receptor; Belongs to the G-protein coupled receptor 2 family. (410 aa)
ENSMNEP00000044158Protein kinase domain-containing protein. (279 aa)
GIPC1GIPC PDZ domain containing family member 1. (333 aa)
TNRTenascin R. (1358 aa)
SYT7Synaptotagmin 7. (686 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
APPAmyloid beta precursor protein. (770 aa)
CPEB3Cytoplasmic polyadenylation element binding protein 3. (721 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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