STRINGSTRING
APOA5 APOA5 ANGPT1 ANGPT1 TNK2 TNK2 EFNB2 EFNB2 NECAB2 NECAB2 PICK1 PICK1 HIP1 HIP1 TF TF CLU CLU ANXA2 ANXA2 ADIPOQ ADIPOQ ENSMNEP00000040501 ENSMNEP00000040501 RABGEF1 RABGEF1 PPP3R1 PPP3R1 HIP1R HIP1R BICD1 BICD1 RIN3 RIN3 DTNBP1 DTNBP1 DGKD DGKD HNRNPK HNRNPK CCL19 CCL19 DLG4 DLG4 PIK3CB PIK3CB MKLN1 MKLN1 LRRTM1 LRRTM1 GSG1L GSG1L ARRB2 ARRB2 B2M B2M AHI1 AHI1 ENSMNEP00000002319 ENSMNEP00000002319 ITGAV ITGAV PLCG2 PLCG2 INSR INSR ANKRD13B ANKRD13B FLOT1 FLOT1 CLUL1 CLUL1 SYK SYK RAB21 RAB21 UBQLN2 UBQLN2 LOC105477893 LOC105477893 ARF1 ARF1 WNT3A WNT3A ABCA2 ABCA2 PPT1 PPT1 PCSK9 PCSK9 NEU3 NEU3 ATXN2 ATXN2 WASL WASL WDR54 WDR54 ARF6 ARF6 ANKRD13D ANKRD13D CD2AP CD2AP RSPO1 RSPO1 NUMB NUMB SNAP91 SNAP91 SMAP1 SMAP1 EGF EGF HPCAL1 HPCAL1 APELA APELA SELE SELE CD63 CD63 AAK1 AAK1 ANKRD13A ANKRD13A USH1G USH1G CBL CBL LRRTM2 LRRTM2 OPHN1 OPHN1 ARC ARC ENSMNEP00000013458 ENSMNEP00000013458 SGIP1 SGIP1 LRPAP1 LRPAP1 DKK1 DKK1 PICALM PICALM HPCA HPCA SFRP4 SFRP4 DRD4 DRD4 FMR1 FMR1 APLN APLN SH3GL3 SH3GL3 SERPINE1 SERPINE1 LDLRAP1 LDLRAP1 HFE HFE ENSMNEP00000007269 ENSMNEP00000007269 ENSMNEP00000007493 ENSMNEP00000007493 GSG1 GSG1 ITGB3 ITGB3 DNM2 DNM2 SCRIB SCRIB DAB2 DAB2 ATAD1 ATAD1 LRRC1 LRRC1 DNAJC6 DNAJC6 APOC2 APOC2 ENSMNEP00000030578 ENSMNEP00000030578 BMP2K BMP2K C3 C3 NRG1 NRG1 SCYL2 SCYL2 SDCBP SDCBP UNC119 UNC119 TBC1D5 TBC1D5 NTF3 NTF3 SYNJ1 SYNJ1 ENSMNEP00000034429 ENSMNEP00000034429 MAGI2 MAGI2 ARRB1 ARRB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APOA5Apolipoprotein A5. (366 aa)
ANGPT1Angiopoietin 1. (498 aa)
TNK2Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (336 aa)
NECAB2N-terminal EF-hand calcium binding protein 2. (386 aa)
PICK1Protein interacting with PRKCA 1. (414 aa)
HIP1Huntingtin interacting protein 1. (968 aa)
TFTransferrin; Belongs to the transferrin family. (698 aa)
CLUClusterin. (534 aa)
ANXA2Annexin. (357 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (274 aa)
ENSMNEP00000040501AAA domain-containing protein; Belongs to the AAA ATPase family. (342 aa)
RABGEF1A20-type domain-containing protein. (469 aa)
PPP3R1Uncharacterized protein. (189 aa)
HIP1RHuntingtin interacting protein 1 related. (1068 aa)
BICD1BICD cargo adaptor 1. (975 aa)
RIN3Ras and Rab interactor 3. (982 aa)
DTNBP1Dystrobrevin binding protein 1. (350 aa)
DGKDDiacylglycerol kinase. (1216 aa)
HNRNPKHeterogeneous nuclear ribonucleoprotein K. (464 aa)
CCL19C-C motif chemokine. (123 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (767 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
MKLN1Muskelin 1. (735 aa)
LRRTM1Leucine rich repeat transmembrane neuronal 1. (522 aa)
GSG1LGSG1 like. (195 aa)
ARRB2Arrestin beta 2. (454 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa)
AHI1Abelson helper integration site 1. (1155 aa)
ENSMNEP00000002319Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (226 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1017 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
INSRTyrosine-protein kinase receptor. (1306 aa)
ANKRD13BAnkyrin repeat domain 13B. (626 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
CLUL1Clusterin; Belongs to the clusterin family. (518 aa)
SYKTyrosine-protein kinase. (629 aa)
RAB21RAB21, member RAS oncogene family. (223 aa)
UBQLN2Ubiquilin 2. (624 aa)
LOC105477893Uncharacterized protein. (1747 aa)
ARF1ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
ABCA2ATP binding cassette subfamily A member 2. (2406 aa)
PPT1Palmitoyl-protein thioesterase 1. (335 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9; Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway. May prevent the recycling of LDLR from endosomes to [...] (811 aa)
NEU3Neuraminidase 3. (461 aa)
ATXN2Ataxin 2. (1217 aa)
WASLWASP like actin nucleation promoting factor. (505 aa)
WDR54WD repeat domain 54. (334 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (148 aa)
ANKRD13DAnkyrin repeat domain 13D. (605 aa)
CD2APCD2 associated protein. (639 aa)
RSPO1R-spondin 1. (262 aa)
NUMBNUMB endocytic adaptor protein. (652 aa)
SNAP91Synaptosome associated protein 91. (907 aa)
SMAP1Small ArfGAP 1. (460 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1166 aa)
HPCAL1Hippocalcin like 1. (193 aa)
APELAUncharacterized protein. (54 aa)
SELESelectin E. (612 aa)
CD63Tetraspanin. (238 aa)
AAK1AP2 associated kinase 1. (962 aa)
ANKRD13AAnkyrin repeat domain 13A. (584 aa)
USH1GUSH1 protein network component sans. (461 aa)
CBLCbl proto-oncogene. (907 aa)
LRRTM2Leucine rich repeat transmembrane neuronal 2. (516 aa)
OPHN1Oligophrenin 1. (802 aa)
ARCActivity regulated cytoskeleton associated protein. (471 aa)
ENSMNEP00000013458PDZ domain-containing protein. (259 aa)
SGIP1SH3 domain GRB2 like endophilin interacting protein 1. (859 aa)
LRPAP1LDL receptor related protein associated protein 1. (358 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (686 aa)
HPCAHippocalcin. (193 aa)
SFRP4Secreted frizzled related protein 4. (368 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (380 aa)
FMR1Fragile X mental retardation 1. (632 aa)
APLNApelin. (77 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (354 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (379 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (308 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (348 aa)
ENSMNEP00000007269VPS9 domain-containing protein. (363 aa)
ENSMNEP00000007493Uncharacterized protein. (283 aa)
GSG1Germ cell associated 1. (340 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
SCRIBScribble planar cell polarity protein. (1698 aa)
DAB2DAB adaptor protein 2. (770 aa)
ATAD1AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
LRRC1Leucine rich repeat containing 1. (524 aa)
DNAJC6DnaJ heat shock protein family (Hsp40) member C6. (913 aa)
APOC2Apolipoprotein C2. (101 aa)
ENSMNEP00000030578PDZ domain-containing protein. (262 aa)
BMP2KBMP2 inducible kinase. (1153 aa)
C3Complement C3. (1642 aa)
NRG1Neuregulin 1. (645 aa)
SCYL2SCY1 like pseudokinase 2. (933 aa)
SDCBPSyndecan binding protein. (318 aa)
UNC119Unc-119 lipid binding chaperone. (240 aa)
TBC1D5TBC1 domain family member 5. (821 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (278 aa)
SYNJ1Synaptojanin 1. (1653 aa)
ENSMNEP00000034429Uncharacterized protein. (291 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1452 aa)
ARRB1Arrestin beta 1. (443 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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