STRINGSTRING
ENSMNEP00000016907 ENSMNEP00000016907 MNAT1 MNAT1 ENSMNEP00000014571 ENSMNEP00000014571 HMOX1 HMOX1 ENSMNEP00000012842 ENSMNEP00000012842 PHB PHB NF1 NF1 MEF2D MEF2D HBEGF HBEGF DNMT1 DNMT1 ITGB3 ITGB3 FOXP1 FOXP1 EDN1 EDN1 LDLRAP1 LDLRAP1 SRC SRC ELANE ELANE ENSMNEP00000005266 ENSMNEP00000005266 P2RY6 P2RY6 IRAK1 IRAK1 S1PR1 S1PR1 RBPMS2 RBPMS2 FOXJ2 FOXJ2 ENSMNEP00000002536 ENSMNEP00000002536 IGF1 IGF1 STAT1 STAT1 IL6 IL6 NOX1 NOX1 DDR2 DDR2 RPS6KB1 RPS6KB1 MFN2 MFN2 IL6R IL6R ENSMNEP00000043817 ENSMNEP00000043817 ITGA2 ITGA2 ERN1 ERN1 SERPINF2 SERPINF2 HES5 HES5 MAP3K5 MAP3K5 SMPD3 SMPD3 IL18 IL18 TGFB1 TGFB1 THBS1 THBS1 ENSMNEP00000037716 ENSMNEP00000037716 TERT TERT TGFBR2 TGFBR2 FGFR2 FGFR2 TLR4 TLR4 CYBA CYBA ZNF143 ZNF143 CCN4 CCN4 IRAK4 IRAK4 EREG EREG ENSMNEP00000032223 ENSMNEP00000032223 ID2 ID2 ADAMTS1 ADAMTS1 NR4A3 NR4A3 IGF1R IGF1R PDGFB PDGFB TNF TNF CALCRL CALCRL HTR1B HTR1B AIF1 AIF1 ENSMNEP00000026182 ENSMNEP00000026182 BMP4 BMP4 AKT1 AKT1 FRS2 FRS2 IGFBP5 IGFBP5 MMP9 MMP9 ALOX12 ALOX12 XBP1 XBP1 NOTCH3 NOTCH3 FGF9 FGF9 PIK3CA PIK3CA PTGS2 PTGS2 PDGFRB PDGFRB CX3CL1 CX3CL1 BMPR1A BMPR1A MMP2 MMP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMNEP00000016907Prohibitin. (173 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (316 aa)
ENSMNEP00000014571Prohibitin. (318 aa)
HMOX1Heme oxygenase 1. (288 aa)
ENSMNEP00000012842Prohibitin. (239 aa)
PHBProhibitin. (272 aa)
NF1Neurofibromin 1. (2839 aa)
MEF2DMyocyte enhancer factor 2D. (521 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1712 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
FOXP1Forkhead box P1. (693 aa)
EDN1Endothelin 1. (211 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (308 aa)
SRCTyrosine-protein kinase. (644 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (263 aa)
ENSMNEP00000005266Prohibitin. (198 aa)
P2RY6Pyrimidinergic receptor P2Y6. (328 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (717 aa)
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
RBPMS2RNA binding protein, mRNA processing factor 2. (209 aa)
FOXJ2Forkhead box J2. (574 aa)
ENSMNEP00000002536Prohibitin. (151 aa)
IGF1Insulin like growth factor 1. (208 aa)
STAT1Signal transducer and activator of transcription. (758 aa)
IL6Interleukin 6. (214 aa)
NOX1NADPH oxidase 1. (564 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (873 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
IL6RInterleukin 6 receptor. (467 aa)
ENSMNEP00000043817Prohibitin. (263 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (978 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (491 aa)
HES5Hes family bHLH transcription factor 5. (166 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1374 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
THBS1Thrombospondin 1. (1173 aa)
ENSMNEP00000037716Prohibitin. (236 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1132 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
FGFR2Fibroblast growth factor receptor. (822 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (826 aa)
CYBACytochrome b-245 alpha chain. (197 aa)
ZNF143Zinc finger protein 143. (638 aa)
CCN4Cellular communication network factor 4. (367 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (460 aa)
EREGEpiregulin. (169 aa)
ENSMNEP00000032223Prohibitin. (133 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif 1. (967 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (637 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
CALCRLCalcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (472 aa)
HTR1B5-hydroxytryptamine receptor 1B. (390 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
ENSMNEP00000026182Prohibitin. (238 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
FRS2Fibroblast growth factor receptor substrate 2. (515 aa)
IGFBP5Insulin like growth factor binding protein 5. (272 aa)
MMP9Matrix metallopeptidase 9. (694 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S type. (663 aa)
XBP1BZIP domain-containing protein. (380 aa)
NOTCH3Notch receptor 3. (2275 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (407 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
MMP2Matrix metallopeptidase 2. (660 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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