66 items (Macaca nemestrina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TUB	Tubby-like protein; Belongs to the TUB family. (562 aa)
	AHSG	Alpha 2-HS glycoprotein. (367 aa)
	RAB27A	RAB27A, member RAS oncogene family. (221 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
	SIRPA	Uncharacterized protein. (507 aa)
	DOCK2	Dedicator of cytokinesis 2; Belongs to the DOCK family. (1830 aa)
	SIRPG	Signal regulatory protein gamma. (387 aa)
	ENSMNEP00000007926	Uncharacterized protein. (483 aa)
	CD36	CD36 molecule; Belongs to the CD36 family. (472 aa)
	STAP1	Signal transducing adaptor family member 1. (295 aa)
	IL15RA	Interleukin 15 receptor subunit alpha. (301 aa)
	DNM2	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
	GATA2	GATA binding protein 2. (480 aa)
	MFGE8	Milk fat globule-EGF factor 8 protein. (387 aa)
	BCR	BCR activator of RhoGEF and GTPase. (1271 aa)
	NCKAP1L	NCK associated protein 1 like. (1134 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (1310 aa)
	IL2RG	Fibronectin type-III domain-containing protein. (369 aa)
	RAB31	RAB31, member RAS oncogene family. (194 aa)
	MASP1	Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family. (730 aa)
	PTX3	Pentraxin 3. (392 aa)
	NOD2	Nucleotide binding oligomerization domain containing 2. (1044 aa)
	SIRPD	Signal regulatory protein delta. (198 aa)
	ANO6	Anoctamin. (931 aa)
	SFTPD	Surfactant protein D. (375 aa)
	APOA2	Apolipoprotein A2. (132 aa)
	FCGR1A	Uncharacterized protein. (357 aa)
	COLEC11	Collectin subfamily member 11. (280 aa)
	SIRPB1	Uncharacterized protein. (422 aa)
	AZU1	Azurocidin 1. (250 aa)
	MERTK	MER proto-oncogene, tyrosine kinase. (989 aa)
	MYO18A	Myosin XVIIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2054 aa)
	CALR	Calreticulin. (417 aa)
	LOC105485223	NTR domain-containing protein. (131 aa)
	PLA2G5	Phospholipase A(2). (138 aa)
	ABCA7	ATP binding cassette subfamily A member 7. (2128 aa)
	COLEC10	Collectin subfamily member 10. (277 aa)
	TREM2	Triggering receptor expressed on myeloid cells 2. (230 aa)
	GAS6	Growth arrest specific 6. (683 aa)
	BTK	Tyrosine-protein kinase. (659 aa)
	LOC105477893	Uncharacterized protein. (1747 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
	LMAN2	Lectin, mannose binding 2. (356 aa)
	TULP1	Tubby-like protein; Belongs to the TUB family. (542 aa)
	FCN3	Ficolin 3. (299 aa)
	CD300LF	CD300 molecule like family member f. (294 aa)
	FCN2	Ficolin 2. (337 aa)
	C3	Complement C3. (1642 aa)
	APPL2	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (786 aa)
	IL1B	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
	CAMK1D	Calcium/calmodulin dependent protein kinase ID; Belongs to the protein kinase superfamily. (385 aa)
	IL15	Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
	CD47	CD47 molecule. (323 aa)
	CYBA	Cytochrome b-245 alpha chain. (197 aa)
	CLEC7A	C-type lectin domain containing 7A. (247 aa)
	MBL2	Mannose binding lectin 2. (255 aa)
	APOA1	Apolipoprotein A1. (267 aa)
	PYCARD	PYD and CARD domain containing. (195 aa)
	C4A	Uncharacterized protein. (1744 aa)
	MASP2	Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family. (686 aa)
	IL2RB	Interleukin 2 receptor subunit beta. (551 aa)
	SLC11A1	Solute carrier family 11 member 1. (477 aa)
	PTPRJ	Protein tyrosine phosphatase receptor type J. (1340 aa)
	ITGA2	Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
	LYAR	Ly1 antibody reactive. (379 aa)
	LOC105465950	C-type lectin domain-containing protein. (249 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA7	TREM2	ENSMNEP00000023061	ENSMNEP00000026141	ATP binding cassette subfamily A member 7.	Triggering receptor expressed on myeloid cells 2.	0.601
AHSG	APOA2	ENSMNEP00000001403	ENSMNEP00000000098	Alpha 2-HS glycoprotein.	Apolipoprotein A2.	0.922
APOA1	APOA2	ENSMNEP00000035632	ENSMNEP00000000098	Apolipoprotein A1.	Apolipoprotein A2.	0.821
APOA2	AHSG	ENSMNEP00000000098	ENSMNEP00000001403	Apolipoprotein A2.	Alpha 2-HS glycoprotein.	0.922
APOA2	APOA1	ENSMNEP00000000098	ENSMNEP00000035632	Apolipoprotein A2.	Apolipoprotein A1.	0.821
APPL2	RAB31	ENSMNEP00000032952	ENSMNEP00000014771	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	RAB31, member RAS oncogene family.	0.868
BTK	IL2RB	ENSMNEP00000027450	ENSMNEP00000039786	Tyrosine-protein kinase.	Interleukin 2 receptor subunit beta.	0.462
BTK	NCKAP1L	ENSMNEP00000027450	ENSMNEP00000012123	Tyrosine-protein kinase.	NCK associated protein 1 like.	0.531
BTK	PLCG2	ENSMNEP00000027450	ENSMNEP00000003170	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.970
C3	C4A	ENSMNEP00000031258	ENSMNEP00000037486	Complement C3.	Uncharacterized protein.	0.894
C3	FCN3	ENSMNEP00000031258	ENSMNEP00000030863	Complement C3.	Ficolin 3.	0.406
C3	LOC105465950	ENSMNEP00000031258	ENSMNEP00000044168	Complement C3.	C-type lectin domain-containing protein.	0.457
C3	LOC105477893	ENSMNEP00000031258	ENSMNEP00000028254	Complement C3.	Uncharacterized protein.	0.566
C3	LOC105485223	ENSMNEP00000031258	ENSMNEP00000022146	Complement C3.	NTR domain-containing protein.	0.894
C3	MASP1	ENSMNEP00000031258	ENSMNEP00000014827	Complement C3.	Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family.	0.725
C3	MASP2	ENSMNEP00000031258	ENSMNEP00000037945	Complement C3.	Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family.	0.841
C3	MBL2	ENSMNEP00000031258	ENSMNEP00000035173	Complement C3.	Mannose binding lectin 2.	0.666
C4A	C3	ENSMNEP00000037486	ENSMNEP00000031258	Uncharacterized protein.	Complement C3.	0.894
C4A	FCN3	ENSMNEP00000037486	ENSMNEP00000030863	Uncharacterized protein.	Ficolin 3.	0.565
C4A	LOC105465950	ENSMNEP00000037486	ENSMNEP00000044168	Uncharacterized protein.	C-type lectin domain-containing protein.	0.924