STRINGSTRING
ENSMNEP00000025089 ENSMNEP00000025089 NCK1 NCK1 FOXP3 FOXP3 NFKBIZ NFKBIZ EGR3 EGR3 ACTL6B ACTL6B SART1 SART1 ENSMNEP00000024033 ENSMNEP00000024033 TNFSF4 TNFSF4 KAT5 KAT5 CORO1A CORO1A CSK CSK IL6ST IL6ST VCAM1 VCAM1 EFNB1 EFNB1 LEP LEP YES1 YES1 HHLA2 HHLA2 ENSMNEP00000021409 ENSMNEP00000021409 SMARCD2 SMARCD2 XBP1 XBP1 BCL6 BCL6 FCHO1 FCHO1 CD24 CD24 PIK3CA PIK3CA IL4 IL4 SMARCB1 SMARCB1 PIK3R6 PIK3R6 LOC105470432 LOC105470432 SIRPB1 SIRPB1 VAV1 VAV1 CD28 CD28 DNAJA3 DNAJA3 CCDC88B CCDC88B CD3E CD3E ARID2 ARID2 CD209 CD209 AGER AGER SMARCD3 SMARCD3 PBRM1 PBRM1 RASGRP1 RASGRP1 HLA-DMA HLA-DMA MAP3K8 MAP3K8 SIRPD SIRPD ITPKB ITPKB IL12RB2 IL12RB2 STAT5B STAT5B IL4R IL4R ZBTB1 ZBTB1 TNFSF9 TNFSF9 ADA ADA CD70 CD70 AP3D1 AP3D1 RPS3 RPS3 TNFSF13B TNFSF13B CD86 CD86 ENSMNEP00000015304 ENSMNEP00000015304 TNFSF11 TNFSF11 IL7R IL7R SMARCA4 SMARCA4 JAK2 JAK2 IL4I1 IL4I1 IL2RG IL2RG IL1RL2 IL1RL2 CD6 CD6 IL21 IL21 ENSMNEP00000013168 ENSMNEP00000013168 CCR7 CCR7 PTPRC PTPRC VSIR VSIR ENSMNEP00000012406 ENSMNEP00000012406 NCKAP1L NCKAP1L PTPN22 PTPN22 ENSMNEP00000012002 ENSMNEP00000012002 NFKBID NFKBID SHB SHB EFNB3 EFNB3 HLA-DPB1 HLA-DPB1 ICOSLG ICOSLG ICOS ICOS RARA RARA DUSP10 DUSP10 ZP4 ZP4 GLI2 GLI2 PNP PNP CBFB CBFB LOC105474889 LOC105474889 CD80 CD80 CD55 CD55 ANXA1 ANXA1 FYN FYN ENSMNEP00000007926 ENSMNEP00000007926 SIRPG SIRPG ABL1 ABL1 PRKCQ PRKCQ SOX13 SOX13 SRC SRC PHF10 PHF10 THY1 THY1 IL12RB1 IL12RB1 WNT10B WNT10B PDCD1LG2 PDCD1LG2 LOC105470433 LOC105470433 IL2 IL2 EPHB6 EPHB6 CARD11 CARD11 IL6 IL6 TNFRSF14 TNFRSF14 CD81 CD81 IGF1 IGF1 MDK MDK RAG1 RAG1 CD27 CD27 HLA-DOA HLA-DOA RHOH RHOH SMARCE1 SMARCE1 ENSMNEP00000002245 ENSMNEP00000002245 SOCS5 SOCS5 SOX12 SOX12 IL36B IL36B SOCS1 SOCS1 CD5 CD5 SIRPA SIRPA HLA-DRA HLA-DRA GLI3 GLI3 SOX4 SOX4 ARID1B ARID1B PTPN11 PTPN11 ENSMNEP00000004521 ENSMNEP00000004521 CCL19 CCL19 CD1D CD1D IFNG IFNG RUNX1 RUNX1 CAV1 CAV1 SMARCD1 SMARCD1 BAD BAD IL27RA IL27RA LOC105474426 LOC105474426 GATA3 GATA3 SLC7A1 SLC7A1 DHPS DHPS LOC105474413 LOC105474413 SMARCC2 SMARCC2 CD274 CD274 IL12A IL12A FLOT2 FLOT2 NLRP3 NLRP3 VTCN1 VTCN1 SMARCC1 SMARCC1 RASAL3 RASAL3 HLA-DOB HLA-DOB LEF1 LEF1 AP3B1 AP3B1 CD160 CD160 ENSMNEP00000040701 ENSMNEP00000040701 TNFRSF13C TNFRSF13C CD4 CD4 IL18 IL18 TGFB1 TGFB1 DOCK8 DOCK8 Mane-DRB1 Mane-DRB1 IHH IHH CD83 CD83 ENSMNEP00000038649 ENSMNEP00000038649 ZBTB7B ZBTB7B RHOA RHOA SHH SHH TRAF6 TRAF6 VNN1 VNN1 MYB MYB RIPK2 RIPK2 SMARCA2 SMARCA2 ZMIZ1 ZMIZ1 KITLG KITLG ENSMNEP00000037627 ENSMNEP00000037627 TNFSF14 TNFSF14 LYN LYN SPTA1 SPTA1 TMIGD2 TMIGD2 ADAM8 ADAM8 TESPA1 TESPA1 AMBRA1 AMBRA1 ENSMNEP00000036565 ENSMNEP00000036565 PYCARD PYCARD IL23R IL23R HAVCR2 HAVCR2 BCL10 BCL10 GPAM GPAM TGFBR2 TGFBR2 MALT1 MALT1 HLA-DPA1 HLA-DPA1 BTN2A2 BTN2A2 JAK3 JAK3 LGALS1 LGALS1 IGFBP2 IGFBP2 IL15 IL15 ENSMNEP00000033549 ENSMNEP00000033549 IL1B IL1B ARID1A ARID1A TFRC TFRC CD40LG CD40LG NCK2 NCK2 PCK1 PCK1 TYK2 TYK2 IL7 IL7 HLA-DQA1 HLA-DQA1 PTPN6 PTPN6 EFNB2 EFNB2 RUNX3 RUNX3 FADD FADD PRKCZ PRKCZ ZBTB16 ZBTB16 SYK SYK LOC105496925 LOC105496925 FAM49B FAM49B ZAP70 ZAP70 ENSMNEP00000027695 ENSMNEP00000027695 CD276 CD276 PPP3CA PPP3CA HLX HLX LCK LCK AIF1 AIF1 ABL2 ABL2 CD74 CD74 DPP4 DPP4 AKT1 AKT1 IGF2 IGF2 SLAMF1 SLAMF1 IL23A IL23A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMNEP00000025089Ig-like domain-containing protein. (235 aa)
NCK1Cytoplasmic protein. (377 aa)
FOXP3Forkhead box P3. (456 aa)
NFKBIZNFKB inhibitor zeta. (719 aa)
EGR3Early growth response 3. (387 aa)
ACTL6BActin like 6B; Belongs to the actin family. (447 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (800 aa)
ENSMNEP00000024033Uncharacterized protein. (265 aa)
TNFSF4TNF superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
CSKTyrosine-protein kinase. (450 aa)
IL6STInterleukin 6 signal transducer. (942 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (346 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
YES1Tyrosine-protein kinase. (548 aa)
HHLA2HERV-H LTR-associating 2. (426 aa)
ENSMNEP00000021409Uncharacterized protein. (123 aa)
SMARCD2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (531 aa)
XBP1BZIP domain-containing protein. (380 aa)
BCL6BCL6 transcription repressor. (708 aa)
FCHO1FCH domain only 1. (872 aa)
CD24Uncharacterized protein. (127 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (867 aa)
LOC105470432Ig-like domain-containing protein; Belongs to the MHC class II family. (260 aa)
SIRPB1Uncharacterized protein. (422 aa)
VAV1Vav guanine nucleotide exchange factor 1. (846 aa)
CD28CD28 molecule. (220 aa)
DNAJA3DnaJ heat shock protein family (Hsp40) member A3. (480 aa)
CCDC88BCoiled-coil domain containing 88B. (1476 aa)
CD3ECD3e molecule. (198 aa)
ARID2AT-rich interaction domain 2. (1836 aa)
CD209CD209 antigen; Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response. Probably recognizes in a calcium- dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens (By similarity). (413 aa)
AGERAdvanced glycosylation end-product specific receptor. (414 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (508 aa)
PBRM1Polybromo 1. (1709 aa)
RASGRP1RAS guanyl releasing protein 1. (832 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (290 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (572 aa)
SIRPDSignal regulatory protein delta. (198 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (945 aa)
IL12RB2Interleukin 12 receptor subunit beta 2. (842 aa)
STAT5BSignal transducer and activator of transcription. (783 aa)
IL4RInterleukin 4 receptor. (825 aa)
ZBTB1Zinc finger and BTB domain containing 1. (644 aa)
TNFSF9TNF superfamily member 9; Belongs to the tumor necrosis factor family. (251 aa)
ADAAdenosine deaminase. (449 aa)
CD70TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (316 aa)
AP3D1Adaptor related protein complex 3 subunit delta 1. (1325 aa)
RPS3KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (284 aa)
TNFSF13BTNF superfamily member 13b; Belongs to the tumor necrosis factor family. (285 aa)
CD86CD86 molecule. (329 aa)
ENSMNEP00000015304Uncharacterized protein. (358 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
IL7RInterleukin 7 receptor. (459 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1677 aa)
JAK2Tyrosine-protein kinase. (1139 aa)
IL4I1Amine oxidase. (589 aa)
IL2RGFibronectin type-III domain-containing protein. (369 aa)
IL1RL2Interleukin 1 receptor like 2. (562 aa)
CD6CD6 molecule. (699 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
ENSMNEP00000013168Ribosomal_S3_C domain-containing protein. (225 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1310 aa)
VSIRV-set immunoregulatory receptor. (311 aa)
ENSMNEP00000012406Uncharacterized protein. (72 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (813 aa)
ENSMNEP00000012002TNF receptor-associated factor. (457 aa)
NFKBIDNFKB inhibitor delta. (469 aa)
SHBSH2 domain containing adaptor protein B. (509 aa)
EFNB3Ephrin B3; Belongs to the ephrin family. (340 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (268 aa)
ICOSLGUncharacterized protein. (302 aa)
ICOSInducible T cell costimulator. (199 aa)
RARARetinoic acid receptor alpha. (477 aa)
DUSP10Dual specificity phosphatase 10. (488 aa)
ZP4Zona pellucida glycoprotein 4. (538 aa)
GLI2GLI family zinc finger 2. (1586 aa)
PNPPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa)
CBFBCore-binding factor subunit beta. (182 aa)
LOC105474889AIG1-type G domain-containing protein. (307 aa)
CD80CD80 molecule. (288 aa)
CD55CD55 molecule (Cromer blood group). (551 aa)
ANXA1Annexin. (346 aa)
FYNTyrosine-protein kinase. (537 aa)
ENSMNEP00000007926Uncharacterized protein. (483 aa)
SIRPGSignal regulatory protein gamma. (387 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
SOX13SRY-box transcription factor 13. (621 aa)
SRCTyrosine-protein kinase. (644 aa)
PHF10PHD finger protein 10. (498 aa)
THY1Thy-1 cell surface antigen. (161 aa)
IL12RB1Interleukin 12 receptor subunit beta 1. (678 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
PDCD1LG2Programmed cell death 1 ligand 2. (273 aa)
LOC105470433MHC class II antigen. (260 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (154 aa)
EPHB6EPH receptor B6. (1017 aa)
CARD11Caspase recruitment domain family member 11. (1154 aa)
IL6Interleukin 6. (214 aa)
TNFRSF14TNF receptor superfamily member 14. (280 aa)
CD81Tetraspanin. (274 aa)
IGF1Insulin like growth factor 1. (208 aa)
MDKMidkine. (168 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa)
CD27CD27 molecule. (260 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa)
RHOHUncharacterized protein. (191 aa)
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa)
ENSMNEP00000002245Ig-like domain-containing protein. (232 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
SOX12Transcription factor SOX. (314 aa)
IL36BInterleukin 36 beta. (164 aa)
SOCS1Suppressor of cytokine signaling 1. (213 aa)
CD5CD5 molecule. (499 aa)
SIRPAUncharacterized protein. (507 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
GLI3GLI family zinc finger 3. (1580 aa)
SOX4Transcription factor SOX. (475 aa)
ARID1BAT-rich interaction domain 1B. (1539 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
ENSMNEP00000004521Ig-like domain-containing protein. (230 aa)
CCL19C-C motif chemokine. (123 aa)
CD1DCD1d molecule. (337 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa)
BADBCL2 associated agonist of cell death. (167 aa)
IL27RAInterleukin 27 receptor subunit alpha. (636 aa)
LOC105474426Ig-like domain-containing protein. (263 aa)
GATA3GATA binding protein 3. (444 aa)
SLC7A1Solute carrier family 7 member 1. (629 aa)
DHPSUncharacterized protein. (369 aa)
LOC105474413Ig-like domain-containing protein. (295 aa)
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1268 aa)
CD274CD274 molecule. (318 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (505 aa)
NLRP3NLR family pyrin domain containing 3. (1035 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (285 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1105 aa)
RASAL3RAS protein activator like 3. (1011 aa)
HLA-DOBMajor histocompatibility complex, class II, DO beta. (285 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa)
CD160CD160 molecule. (181 aa)
ENSMNEP00000040701Uncharacterized protein. (164 aa)
TNFRSF13CTNF receptor superfamily member 13C. (172 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2096 aa)
Mane-DRB1MHC class II protein. (266 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
CD83CD83 molecule. (205 aa)
ENSMNEP00000038649Ig-like domain-containing protein. (235 aa)
ZBTB7BZinc finger and BTB domain containing 7B. (573 aa)
RHOARas homolog family member A. (193 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (462 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
VNN1Vanin 1. (513 aa)
MYBMYB proto-oncogene, transcription factor. (761 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1583 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1073 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
ENSMNEP00000037627Uncharacterized protein. (339 aa)
TNFSF14TNF superfamily member 14; Belongs to the tumor necrosis factor family. (240 aa)
LYNTyrosine-protein kinase. (512 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2420 aa)
TMIGD2Transmembrane and immunoglobulin domain containing 2. (170 aa)
ADAM8ADAM metallopeptidase domain 8. (824 aa)
TESPA1Thymocyte expressed, positive selection associated 1. (521 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1298 aa)
ENSMNEP00000036565HMG box domain-containing protein. (177 aa)
PYCARDPYD and CARD domain containing. (195 aa)
IL23RInterleukin 23 receptor. (576 aa)
HAVCR2Hepatitis A virus cellular receptor 2. (294 aa)
BCL10BCL10 immune signaling adaptor. (233 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
MALT1MALT1 paracaspase. (824 aa)
HLA-DPA1Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa)
BTN2A2Uncharacterized protein. (519 aa)
JAK3Tyrosine-protein kinase. (1088 aa)
LGALS1Galectin. (135 aa)
IGFBP2Insulin like growth factor binding protein 2. (326 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
ENSMNEP00000033549Uncharacterized protein. (168 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
ARID1AAT-rich interaction domain 1A. (2290 aa)
TFRCTransferrin receptor. (764 aa)
CD40LGCD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] (261 aa)
NCK2Cytoplasmic protein. (382 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
TYK2Tyrosine-protein kinase. (1190 aa)
IL7Interleukin 7. (184 aa)
HLA-DQA1Major histocompatibility complex, class II, DQ alpha 1; Belongs to the MHC class II family. (267 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (336 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (429 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
SYKTyrosine-protein kinase. (629 aa)
LOC105496925Rho-related GTP-binding protein RhoH. (191 aa)
FAM49BFamily with sequence similarity 49 member B. (365 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
ENSMNEP00000027695Uncharacterized protein. (445 aa)
CD276CD276 molecule. (534 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
HLXH2.0 like homeobox. (495 aa)
LCKTyrosine-protein kinase. (540 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
ABL2Tyrosine-protein kinase. (1182 aa)
CD74CD74 molecule. (294 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (766 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
IGF2Insulin like growth factor 2. (236 aa)
SLAMF1Signaling lymphocytic activation molecule family member 1. (356 aa)
IL23AInterleukin 23 subunit alpha. (189 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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