STRINGSTRING
TRIM25 TRIM25 ANKRD42 ANKRD42 TRIM26 TRIM26 ZC4H2 ZC4H2 ENSMNEP00000044641 ENSMNEP00000044641 RTKN2 RTKN2 CAV1 CAV1 ARHGEF5 ARHGEF5 UBE2N UBE2N DDIT3 DDIT3 IKBKG IKBKG DDR2 DDR2 NEUROD1 NEUROD1 CARD11 CARD11 SAV1 SAV1 IL6 IL6 CTNNB1 CTNNB1 ENSMNEP00000001266 ENSMNEP00000001266 NHLH2 NHLH2 ENSMNEP00000001510 ENSMNEP00000001510 NEUROG2 NEUROG2 TRIM22 TRIM22 IL5 IL5 ROR1 ROR1 CD40 CD40 PSMA6 PSMA6 TRIM32 TRIM32 LPAR5 LPAR5 CTH CTH NEUROG1 NEUROG1 LAMTOR5 LAMTOR5 EPHA5 EPHA5 PLCG2 PLCG2 LOC105499496 LOC105499496 PRKD1 PRKD1 SPHK1 SPHK1 ENSMNEP00000003725 ENSMNEP00000003725 MBTPS2 MBTPS2 TRADD TRADD ENSMNEP00000004092 ENSMNEP00000004092 ENSMNEP00000004093 ENSMNEP00000004093 TRAF2 TRAF2 WNT5A WNT5A CIB1 CIB1 IRAK2 IRAK2 IRAK1 IRAK1 CRTC1 CRTC1 WNT10B WNT10B NEUROD2 NEUROD2 TNFRSF11A TNFRSF11A RIPK4 RIPK4 ENSMNEP00000005430 ENSMNEP00000005430 PRKCB PRKCB CEBPG CEBPG TRIM21 TRIM21 EDA2R EDA2R THAP11 THAP11 PRKCQ PRKCQ PTEN PTEN TRIM14 TRIM14 CSF3 CSF3 STK3 STK3 ENSMNEP00000007520 ENSMNEP00000007520 TRIM27 TRIM27 ENSMNEP00000007919 ENSMNEP00000007919 RAB7B RAB7B EDN1 EDN1 CD36 CD36 PPARGC1A PPARGC1A ADCY1 ADCY1 PIDD1 PIDD1 ADGRF1 ADGRF1 FZD4 FZD4 TRIM15 TRIM15 AR AR NKX3-1 NKX3-1 ENSMNEP00000010524 ENSMNEP00000010524 RIPK1 RIPK1 TRAPPC9 TRAPPC9 DDRGK1 DDRGK1 ENSMNEP00000010989 ENSMNEP00000010989 ANXA3 ANXA3 TRIM5 TRIM5 FANK1 FANK1 NTSR1 NTSR1 DVL2 DVL2 ARHGEF2 ARHGEF2 PARK7 PARK7 ENSMNEP00000012002 ENSMNEP00000012002 ENSMNEP00000012230 ENSMNEP00000012230 ENSMNEP00000012292 ENSMNEP00000012292 TCF3 TCF3 CHUK CHUK AIM2 AIM2 CARD9 CARD9 ENSMNEP00000013103 ENSMNEP00000013103 ENSMNEP00000013168 ENSMNEP00000013168 TSSK4 TSSK4 ITGB2 ITGB2 CYTL1 CYTL1 TLR3 TLR3 SMARCA4 SMARCA4 CX3CR1 CX3CR1 RIPK3 RIPK3 CLOCK CLOCK TRIML1 TRIML1 PPRC1 PPRC1 TNFSF11 TNFSF11 ENSMNEP00000015849 ENSMNEP00000015849 RPS6KA4 RPS6KA4 RPS3 RPS3 ENSMNEP00000016207 ENSMNEP00000016207 RHEBL1 RHEBL1 ERC1 ERC1 ABRA ABRA NOD2 NOD2 PINK1 PINK1 TNFSF18 TNFSF18 COPS5 COPS5 TAF12 TAF12 IRAK3 IRAK3 ESR2 ESR2 AMH AMH SMAD3 SMAD3 KIT KIT AGER AGER HDAC4 HDAC4 ESR1 ESR1 MTDH MTDH CX3CL1 CX3CL1 STAT3 STAT3 TRIM31 TRIM31 CRTC2 CRTC2 TRIM37 TRIM37 ZBTB7A ZBTB7A ENSMNEP00000020157 ENSMNEP00000020157 S100A9 S100A9 TRIML2 TRIML2 SMARCB1 SMARCB1 SMO SMO PPARGC1B PPARGC1B ENSMNEP00000020734 ENSMNEP00000020734 SLCO3A1 SLCO3A1 BUD31 BUD31 ENSMNEP00000021409 ENSMNEP00000021409 LRP6 LRP6 TIRAP TIRAP ENSMNEP00000022200 ENSMNEP00000022200 FZD2 FZD2 PLA2G1B PLA2G1B DHX33 DHX33 SP100 SP100 ENSMNEP00000022756 ENSMNEP00000022756 TRIM13 TRIM13 FER FER ENSMNEP00000024169 ENSMNEP00000024169 ZIC2 ZIC2 WNT2 WNT2 NFAM1 NFAM1 TRIM41 TRIM41 JUP JUP NODAL NODAL KDM1A KDM1A CARD14 CARD14 AKT1 AKT1 BMP2 BMP2 NOD1 NOD1 RGCC RGCC IL1RAP IL1RAP PPP3CA PPP3CA NDP NDP BTK BTK WNT3A WNT3A FOXA1 FOXA1 CAPN3 CAPN3 LTF LTF IL18RAP IL18RAP RELA RELA CLUL1 CLUL1 FLOT1 FLOT1 PPP2R5B PPP2R5B RPS6KA5 RPS6KA5 PRKCZ PRKCZ ATF2 ATF2 TNF TNF CRTC3 CRTC3 TICAM1 TICAM1 PRKD2 PRKD2 TRIM6 TRIM6 TRIM8 TRIM8 LOC105468609 LOC105468609 TP53BP1 TP53BP1 TRIM68 TRIM68 EDA EDA NPM1 NPM1 RELN RELN HIPK2 HIPK2 TRAF5 TRAF5 CD40LG CD40LG RNF25 RNF25 RNF31 RNF31 STING1 STING1 MYD88 MYD88 TERF2IP TERF2IP PLPP3 PLPP3 TFRC TFRC ENSMNEP00000032418 ENSMNEP00000032418 OPRD1 OPRD1 IL1B IL1B IKBKB IKBKB CAMK1D CAMK1D NTS NTS EIF2AK2 EIF2AK2 RNF220 RNF220 ADCY8 ADCY8 LOC105466675 LOC105466675 ENSMNEP00000034131 ENSMNEP00000034131 TAF1 TAF1 TLR4 TLR4 MALT1 MALT1 BCL10 BCL10 DHX9 DHX9 HCLS1 HCLS1 CRNN CRNN SRF SRF PYCARD PYCARD MAP3K13 MAP3K13 ARID5B ARID5B IL10 IL10 STK36 STK36 ADAM8 ADAM8 IKBKE IKBKE ENSMNEP00000037489 ENSMNEP00000037489 DDX58 DDX58 ENSMNEP00000037725 ENSMNEP00000037725 ALK ALK TRIM52 TRIM52 RIPK2 RIPK2 MID2 MID2 TRAF6 TRAF6 SHH SHH IL18R1 IL18R1 S100A8 S100A8 LRP8 LRP8 TGFB1 TGFB1 IL18 IL18 CLU CLU PRKCI PRKCI JMY JMY EP300 EP300 ENSMNEP00000040701 ENSMNEP00000040701 LOC105491382 LOC105491382 RBCK1 RBCK1 FOSL1 FOSL1 CAT CAT NTRK1 NTRK1 TRIM62 TRIM62 WNT1 WNT1 NLRP3 NLRP3 FLOT2 FLOT2 TRAF1 TRAF1 TRIM38 TRIM38 LRP5 LRP5 TFDP1 TFDP1 RWDD1 RWDD1 MTPN MTPN LOC105480535 LOC105480535 S100A12 S100A12 APP APP HSF1 HSF1 MYOCD MYOCD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRIM25Tripartite motif containing 25. (630 aa)
ANKRD42Ankyrin repeat domain 42. (527 aa)
TRIM26Tripartite motif containing 26. (542 aa)
ZC4H2Zinc finger C4H2-type containing. (224 aa)
ENSMNEP00000044641Uncharacterized protein. (111 aa)
RTKN2Rhotekin 2. (609 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5. (1597 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (411 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (873 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
CARD11Caspase recruitment domain family member 11. (1154 aa)
SAV1Salvador family WW domain containing protein 1. (384 aa)
IL6Interleukin 6. (214 aa)
CTNNB1Catenin beta 1. (781 aa)
ENSMNEP00000001266Uncharacterized protein. (234 aa)
NHLH2Nescient helix-loop-helix 2. (135 aa)
ENSMNEP00000001510Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (155 aa)
NEUROG2Neurogenin 2. (272 aa)
TRIM22Tripartite motif containing 22. (498 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
CD40CD40 molecule. (278 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
TRIM32Tripartite motif containing 32. (596 aa)
LPAR5Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (372 aa)
CTHCystathionine gamma-lyase. (465 aa)
NEUROG1Neurogenin 1. (237 aa)
LAMTOR5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (169 aa)
EPHA5EPH receptor A5. (1038 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
LOC105499496UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (892 aa)
SPHK1Sphingosine kinase 1. (470 aa)
ENSMNEP00000003725Nucleoplasmin domain-containing protein. (218 aa)
MBTPS2Membrane bound transcription factor peptidase, site 2. (517 aa)
TRADDTNFRSF1A associated via death domain. (308 aa)
ENSMNEP00000004092Proteasome subunit alpha type. (231 aa)
ENSMNEP00000004093Uncharacterized protein. (305 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (532 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (419 aa)
CIB1Calcium and integrin binding 1. (231 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (625 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (717 aa)
CRTC1CREB regulated transcription coactivator 1. (650 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
NEUROD2Neurogenic differentiation factor. (382 aa)
TNFRSF11ATNF receptor superfamily member 11a. (616 aa)
RIPK4Receptor interacting serine/threonine kinase 4. (838 aa)
ENSMNEP00000005430Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (165 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
CEBPGCCAAT enhancer binding protein gamma. (150 aa)
TRIM21Tripartite motif containing 21. (475 aa)
EDA2REctodysplasin A2 receptor. (318 aa)
THAP11THAP domain containing 11. (309 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
TRIM14Tripartite motif containing 14. (442 aa)
CSF3Colony stimulating factor 3. (207 aa)
STK3Serine/threonine kinase 3. (519 aa)
ENSMNEP00000007520CARD domain-containing protein. (359 aa)
TRIM27Tripartite motif containing 27. (513 aa)
ENSMNEP00000007919Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (154 aa)
RAB7BRAB7B, member RAS oncogene family. (199 aa)
EDN1Endothelin 1. (211 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
PPARGC1APPARG coactivator 1 alpha. (798 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1088 aa)
PIDD1P53-induced death domain protein 1. (936 aa)
ADGRF1Adhesion G protein-coupled receptor F1; Belongs to the G-protein coupled receptor 2 family. (903 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
TRIM15Tripartite motif containing 15. (465 aa)
ARAndrogen receptor. (898 aa)
NKX3-1NK3 homeobox 1. (232 aa)
ENSMNEP00000010524DJ-1_PfpI domain-containing protein. (186 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (693 aa)
TRAPPC9Trafficking protein particle complex 9. (1100 aa)
DDRGK1DDRGK domain containing 1. (342 aa)
ENSMNEP00000010989Proteasome endopeptidase complex. (241 aa)
ANXA3Annexin. (323 aa)
TRIM5Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1- UBE2N (als [...] (484 aa)
FANK1Fibronectin type III and ankyrin repeat domains 1. (345 aa)
NTSR1Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (418 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (1003 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
ENSMNEP00000012002TNF receptor-associated factor. (457 aa)
ENSMNEP00000012230Uncharacterized protein. (216 aa)
ENSMNEP00000012292Uncharacterized protein. (208 aa)
TCF3Transcription factor 3. (680 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
AIM2Absent in melanoma 2. (343 aa)
CARD9Caspase recruitment domain family member 9. (535 aa)
ENSMNEP00000013103Uncharacterized protein. (90 aa)
ENSMNEP00000013168Ribosomal_S3_C domain-containing protein. (225 aa)
TSSK4Testis specific serine kinase 4. (338 aa)
ITGB2Integrin beta. (921 aa)
CYTL1Cytokine like 1. (136 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1677 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (386 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (518 aa)
CLOCKClock circadian regulator. (851 aa)
TRIML1Tripartite motif family like 1. (447 aa)
PPRC1PPARG related coactivator 1. (1667 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
ENSMNEP00000015849Transcription factor. (392 aa)
RPS6KA4Non-specific serine/threonine protein kinase. (649 aa)
RPS3KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (284 aa)
ENSMNEP00000016207Uncharacterized protein. (253 aa)
RHEBL1RHEB like 1. (183 aa)
ERC1ELKS/RAB6-interacting/CAST family member 1. (1080 aa)
ABRAActin binding Rho activating protein. (381 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1044 aa)
PINK1PTEN induced kinase 1. (581 aa)
TNFSF18TNF superfamily member 18. (199 aa)
COPS5COP9 signalosome subunit 5. (334 aa)
TAF12TATA-box binding protein associated factor 12. (213 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (596 aa)
ESR2Estrogen receptor 2. (530 aa)
AMHAnti-Mullerian hormone. (562 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
AGERAdvanced glycosylation end-product specific receptor. (414 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1094 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
MTDHMetadherin. (535 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (407 aa)
STAT3Signal transducer and activator of transcription. (660 aa)
TRIM31Tripartite motif containing 31. (370 aa)
CRTC2CREB regulated transcription coactivator 2. (694 aa)
TRIM37Tripartite motif containing 37. (963 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (584 aa)
ENSMNEP00000020157Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (121 aa)
S100A9Protein S100; Belongs to the S-100 family. (114 aa)
TRIML2Tripartite motif family like 2. (437 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (657 aa)
PPARGC1BPPARG coactivator 1 beta. (1023 aa)
ENSMNEP00000020734Uncharacterized protein. (74 aa)
SLCO3A1Solute carrier organic anion transporter family member. (692 aa)
BUD31BUD31 homolog. (144 aa)
ENSMNEP00000021409Uncharacterized protein. (123 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
TIRAPTIR domain containing adaptor protein. (234 aa)
ENSMNEP00000022200Uncharacterized protein. (232 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (562 aa)
PLA2G1BPhospholipase A(2). (148 aa)
DHX33DEAH-box helicase 33. (680 aa)
SP100SP100 nuclear antigen. (863 aa)
ENSMNEP00000022756RWD domain-containing protein. (200 aa)
TRIM13Tripartite motif containing 13. (409 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
ENSMNEP00000024169Nucleoplasmin domain-containing protein. (220 aa)
ZIC2Zic family member 2. (521 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
NFAM1NFAT activating protein with ITAM motif 1. (271 aa)
TRIM41Tripartite motif containing 41. (631 aa)
JUPJunction plakoglobin. (745 aa)
NODALNodal growth differentiation factor. (347 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
CARD14Caspase recruitment domain family member 14. (1003 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
RGCCRegulator of cell cycle. (137 aa)
IL1RAPInterleukin 1 receptor accessory protein. (687 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
NDPNorrin cystine knot growth factor NDP. (133 aa)
BTKTyrosine-protein kinase. (659 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
FOXA1Forkhead box A1. (470 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (821 aa)
LTFLactotransferrin; Belongs to the transferrin family. (747 aa)
IL18RAPInterleukin 18 receptor accessory protein. (598 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
CLUL1Clusterin; Belongs to the clusterin family. (518 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (596 aa)
RPS6KA5Ribosomal protein S6 kinase. (802 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
CRTC3CREB regulated transcription coactivator 3. (619 aa)
TICAM1Toll like receptor adaptor molecule 1. (519 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
TRIM6Tripartite motif containing 6. (559 aa)
TRIM8Tripartite motif containing 8. (551 aa)
LOC105468609Uncharacterized protein. (488 aa)
TP53BP1Tumor protein p53 binding protein 1. (1926 aa)
TRIM68Tripartite motif containing 68. (485 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (391 aa)
NPM1Nucleophosmin 1. (294 aa)
RELNReelin. (3460 aa)
HIPK2Homeodomain interacting protein kinase 2. (1198 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa)
CD40LGCD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] (261 aa)
RNF25Ring finger protein 25. (470 aa)
RNF31Uncharacterized protein. (1078 aa)
STING1Transmembrane protein 173. (379 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
TERF2IPTERF2 interacting protein. (400 aa)
PLPP3acidPPc domain-containing protein. (353 aa)
TFRCTransferrin receptor. (764 aa)
ENSMNEP00000032418DJ-1_PfpI domain-containing protein. (166 aa)
OPRD1Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (372 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
CAMK1DCalcium/calmodulin dependent protein kinase ID; Belongs to the protein kinase superfamily. (385 aa)
NTSNeurotensin. (170 aa)
EIF2AK2Eukaryotic translation initiation factor 2 alpha kinase 2. (488 aa)
RNF220Ring finger protein 220. (566 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
LOC105466675UBIQUITIN_CONJUGAT_2 domain-containing protein. (87 aa)
ENSMNEP00000034131DJ-1_PfpI domain-containing protein. (170 aa)
TAF1Transcription initiation factor TFIID subunit. (1875 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (826 aa)
MALT1MALT1 paracaspase. (824 aa)
BCL10BCL10 immune signaling adaptor. (233 aa)
DHX9DExH-box helicase 9. (1275 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (475 aa)
CRNNCornulin. (495 aa)
SRFSerum response factor. (508 aa)
PYCARDPYD and CARD domain containing. (195 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13. (939 aa)
ARID5BAT-rich interaction domain 5B. (1188 aa)
IL10Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa)
STK36Serine/threonine kinase 36. (1315 aa)
ADAM8ADAM metallopeptidase domain 8. (824 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa)
ENSMNEP00000037489Uncharacterized protein. (254 aa)
DDX58DExD/H-box helicase 58. (925 aa)
ENSMNEP00000037725UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
ALKTyrosine-protein kinase receptor. (1620 aa)
TRIM52Tripartite motif containing 52. (296 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
MID2Midline 2. (735 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (462 aa)
IL18R1Interleukin 18 receptor 1. (540 aa)
S100A8Protein S100; Belongs to the S-100 family. (93 aa)
LRP8LDL receptor related protein 8. (959 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
CLUClusterin. (534 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (690 aa)
JMYJunction mediating and regulatory protein, p53 cofactor. (990 aa)
EP300E1A binding protein p300. (2397 aa)
ENSMNEP00000040701Uncharacterized protein. (164 aa)
LOC105491382UBIQUITIN_CONJUGAT_2 domain-containing protein. (87 aa)
RBCK1RANBP2-type and C3HC4-type zinc finger containing 1. (496 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
TRIM62Tripartite motif containing 62. (475 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
NLRP3NLR family pyrin domain containing 3. (1035 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (505 aa)
TRAF1TNF receptor-associated factor. (416 aa)
TRIM38Tripartite motif containing 38. (465 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1599 aa)
TFDP1Transcription factor. (410 aa)
RWDD1RWD domain containing 1. (243 aa)
MTPNMyotrophin. (118 aa)
LOC105480535TIR domain-containing protein. (1033 aa)
S100A12S100 calcium binding protein A12. (81 aa)
APPAmyloid beta precursor protein. (770 aa)
HSF1Heat shock transcription factor 1. (529 aa)
MYOCDMyocardin. (986 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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