STRINGSTRING
BMP10 BMP10 TBX20 TBX20 TGFB1 TGFB1 TGFB2 TGFB2 MED1 MED1 MYL3 MYL3 LOC105499514 LOC105499514 ANKRD1 ANKRD1 HAND1 HAND1 ZFPM2 ZFPM2 XIRP2 XIRP2 ENG ENG TGFBR3 TGFBR3 WNT2 WNT2 TNNI3 TNNI3 BMP2 BMP2 HEY2 HEY2 FOXC2 FOXC2 NOG NOG HEG1 HEG1 NRG1 NRG1 DLL4 DLL4 EDNRA EDNRA FOXC1 FOXC1 PTCD2 PTCD2 RYR2 RYR2 NKX2-5 NKX2-5 LRP2 LRP2 WNT5A WNT5A S1PR1 S1PR1 MYL10 MYL10 COL11A1 COL11A1 TTN TTN MYBPC3 MYBPC3 PKP2 PKP2 NOTCH1 NOTCH1 TNNC1 TNNC1 FOXH1 FOXH1 SMAD4 SMAD4 ENSMNEP00000013651 ENSMNEP00000013651 PROX1 PROX1 TGFBR1 TGFBR1 TCAP TCAP BMPR1A BMPR1A MYLK2 MYLK2 SMAD7 SMAD7 MYH6 MYH6 POU4F1 POU4F1 DSP DSP EGLN1 EGLN1 CHD7 CHD7 FGFR2 FGFR2 TNNT2 TNNT2 ISL1 ISL1 MYL2 MYL2 TNNI1 TNNI1 ZFPM1 ZFPM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMP10Bone morphogenetic protein 10. (424 aa)
TBX20T-box transcription factor 20. (447 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1490 aa)
MYL3Myosin light chain 3. (227 aa)
LOC105499514Uncharacterized protein. (5591 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
XIRP2Xin actin binding repeat containing 2. (3550 aa)
ENGEndoglin. (658 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
TNNI3Troponin I3, cardiac type. (210 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
FOXC2Forkhead box C2. (501 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
HEG1Heart development protein with EGF like domains 1. (1346 aa)
NRG1Neuregulin 1. (645 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
FOXC1Forkhead box C1. (552 aa)
PTCD2Pentatricopeptide repeat domain 2. (383 aa)
RYR2Ryanodine receptor 2. (4951 aa)
NKX2-5NK2 homeobox 5. (324 aa)
LRP2LDL receptor related protein 2. (4655 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (419 aa)
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
MYL10Myosin light chain 10. (226 aa)
COL11A1Collagen type XI alpha 1 chain. (1818 aa)
TTNTitin. (22498 aa)
MYBPC3Myosin binding protein C, cardiac. (1276 aa)
PKP2Plakophilin 2. (869 aa)
NOTCH1Notch receptor 1. (2556 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (161 aa)
FOXH1Forkhead box H1. (366 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ENSMNEP00000013651Uncharacterized protein. (568 aa)
PROX1Prospero homeobox 1. (737 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
TCAPTitin-cap. (167 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
MYLK2Myosin light chain kinase 2. (595 aa)
SMAD7Mothers against decapentaplegic homolog. (488 aa)
MYH6Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
POU4F1POU domain protein. (380 aa)
DSPDesmoplakin. (2272 aa)
EGLN1Egl-9 family hypoxia inducible factor 1. (426 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2998 aa)
FGFR2Fibroblast growth factor receptor. (822 aa)
TNNT2Troponin T2, cardiac type. (302 aa)
ISL1ISL LIM homeobox 1. (349 aa)
MYL2Myosin light chain 2. (166 aa)
TNNI1Troponin I1, slow skeletal type. (187 aa)
ZFPM1Zinc finger protein, FOG family member 1. (976 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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