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ENSMNEP00000001975 ENSMNEP00000001975 ENSMNEP00000002472 ENSMNEP00000002472 ERCC1 ERCC1 MED7 MED7 LOC105498354 LOC105498354 NKX2-5 NKX2-5 WNT10B WNT10B TAF10 TAF10 MED24 MED24 MED30 MED30 TBP TBP PAXIP1 PAXIP1 ENSMNEP00000012207 ENSMNEP00000012207 TAF4B TAF4B GTF2A2 GTF2A2 MED14 MED14 MED22 MED22 MED19 MED19 TAF12 TAF12 ESR1 ESR1 MED11 MED11 MED27 MED27 ENSMNEP00000020161 ENSMNEP00000020161 TAF2 TAF2 MED9 MED9 TAF3 TAF3 MED8 MED8 ENSMNEP00000022472 ENSMNEP00000022472 TAF5 TAF5 MED16 MED16 ENSMNEP00000042381 ENSMNEP00000042381 ENSMNEP00000042090 ENSMNEP00000042090 MED26 MED26 ENSMNEP00000041910 ENSMNEP00000041910 ERCC6 ERCC6 MED1 MED1 TAF13 TAF13 MED13 MED13 MED12 MED12 ENSMNEP00000036869 ENSMNEP00000036869 SRF SRF MED31 MED31 TAF6 TAF6 MED15 MED15 TAF1 TAF1 MED4 MED4 MED18 MED18 DHX36 DHX36 MED21 MED21 MED28 MED28 MED25 MED25 HNF1B HNF1B HNF1A HNF1A MED29 MED29 TAF8 TAF8 SUB1 SUB1 MED23 MED23 TAF4 TAF4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMNEP00000001975Uncharacterized protein. (235 aa)
ENSMNEP00000002472Uncharacterized protein. (245 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (323 aa)
MED7Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (232 aa)
LOC105498354Uncharacterized protein. (998 aa)
NKX2-5NK2 homeobox 5. (324 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
MED24Uncharacterized protein. (1008 aa)
MED30Mediator complex subunit 30. (178 aa)
TBPTATA-box binding protein. (327 aa)
PAXIP1PAX interacting protein 1. (1069 aa)
ENSMNEP00000012207Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (104 aa)
TAF4BTATA-box binding protein associated factor 4b. (862 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
MED14Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1454 aa)
MED22Mediator complex subunit 22. (200 aa)
MED19Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (261 aa)
TAF12TATA-box binding protein associated factor 12. (213 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
MED11Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (117 aa)
MED27Mediator complex subunit 27. (311 aa)
ENSMNEP00000020161Uncharacterized protein. (247 aa)
TAF2TATA-box binding protein associated factor 2. (1186 aa)
MED9Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (146 aa)
TAF3TATA-box binding protein associated factor 3. (931 aa)
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (337 aa)
ENSMNEP00000022472AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
TAF5TATA-box binding protein associated factor 5. (779 aa)
MED16Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (841 aa)
ENSMNEP00000042381Uncharacterized protein. (312 aa)
ENSMNEP00000042090TFIIA_gamma_C domain-containing protein. (74 aa)
MED26TFIIS N-terminal domain-containing protein. (600 aa)
ENSMNEP00000041910Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (197 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1496 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1490 aa)
TAF13TATA-box binding protein associated factor 13. (124 aa)
MED13Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2138 aa)
MED12Mediator complex subunit 12. (2178 aa)
ENSMNEP00000036869Uncharacterized protein. (97 aa)
SRFSerum response factor. (508 aa)
MED31Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa)
TAF6TATA-box binding protein associated factor 6. (719 aa)
MED15Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (788 aa)
TAF1Transcription initiation factor TFIID subunit. (1875 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (270 aa)
MED18Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (208 aa)
DHX36DEAH-box helicase 36. (1008 aa)
MED21Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (160 aa)
MED28Mediator complex subunit 28. (178 aa)
MED25Mediator complex subunit 25. (747 aa)
HNF1BHNF1 homeobox B. (557 aa)
HNF1AHNF1 homeobox A. (662 aa)
MED29Mediator complex subunit 29. (201 aa)
TAF8TATA-box binding protein associated factor 8. (261 aa)
SUB1SUB1 regulator of transcription. (127 aa)
MED23Mediator complex subunit 23. (1329 aa)
TAF4TATA-box binding protein associated factor 4. (635 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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