50 items (Macaca nemestrina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CRK	CRK proto-oncogene, adaptor protein. (304 aa)
	MYADM	Myeloid associated differentiation marker. (322 aa)
	MDK	Midkine. (168 aa)
	ENSMNEP00000045127	Uncharacterized protein. (183 aa)
	DMTN	Dematin actin binding protein. (412 aa)
	PREX1	Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1733 aa)
	C1QBP	Complement C1q binding protein. (281 aa)
	DOCK5	Dedicator of cytokinesis 5; Belongs to the DOCK family. (1860 aa)
	FLNA	Filamin A. (2647 aa)
	P4HB	Prolyl 4-hydroxylase subunit beta; Belongs to the protein disulfide isomerase family. (569 aa)
	TESK1	Testis associated actin remodelling kinase 1. (626 aa)
	TRIOBP	TRIO and F-actin binding protein. (2092 aa)
	LOC105464826	Uncharacterized protein. (316 aa)
	CIB1	Calcium and integrin binding 1. (231 aa)
	ENSMNEP00000004647	Uncharacterized protein. (185 aa)
	LIMS2	LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (365 aa)
	UNC13D	Unc-13 homolog D. (1126 aa)
	LIMS1	LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (398 aa)
	BRAF	B-Raf proto-oncogene, serine/threonine kinase. (763 aa)
	MYOC	Myocilin. (491 aa)
	ABL1	Tyrosine-protein kinase. (1148 aa)
	RAC3	Rac family small GTPase 3. (192 aa)
	LRRC45	Leucine rich repeat containing 45. (670 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (788 aa)
	DNM2	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
	DAB2	DAB adaptor protein 2. (770 aa)
	ENSMNEP00000011554	Uncharacterized protein. (157 aa)
	CARMIL1	Capping protein regulator and myosin 1 linker 1. (1371 aa)
	ENSMNEP00000016378	Protein kinase domain-containing protein. (652 aa)
	OLFM4	Olfactomedin 4. (512 aa)
	CRKL	CRK like proto-oncogene, adaptor protein. (303 aa)
	S100A10	S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa)
	CDC42	Uncharacterized protein. (191 aa)
	FERMT2	Fermitin family member 2. (689 aa)
	FGA	Fibrinogen alpha chain. (862 aa)
	DOCK1	Dedicator of cytokinesis 1; Belongs to the DOCK family. (1886 aa)
	ENSMNEP00000021981	Uncharacterized protein. (161 aa)
	CALR	Calreticulin. (417 aa)
	ARPC2	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (306 aa)
	HAS2	Hyaluronan synthase 2. (552 aa)
	FGB	Fibrinogen beta chain. (491 aa)
	CSPG5	Chondroitin sulfate proteoglycan 5. (556 aa)
	HPSE	Heparanase. (545 aa)
	ENSMNEP00000029022	Uncharacterized protein. (185 aa)
	NEDD9	Neural precursor cell expressed, developmentally down-regulated 9. (839 aa)
	NRP1	Neuropilin; Belongs to the neuropilin family. (925 aa)
	RREB1	Ras responsive element binding protein 1. (1746 aa)
	FGG	Fibrinogen gamma chain. (437 aa)
	ARHGEF7	Rho guanine nucleotide exchange factor 7. (862 aa)
	RAC1	Rac family small GTPase 1. (211 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	CDC42	ENSMNEP00000007383	ENSMNEP00000021122	Tyrosine-protein kinase.	Uncharacterized protein.	0.425
ABL1	CRK	ENSMNEP00000007383	ENSMNEP00000032388	Tyrosine-protein kinase.	CRK proto-oncogene, adaptor protein.	0.992
ABL1	CRKL	ENSMNEP00000007383	ENSMNEP00000019589	Tyrosine-protein kinase.	CRK like proto-oncogene, adaptor protein.	0.999
ABL1	DOCK5	ENSMNEP00000007383	ENSMNEP00000041661	Tyrosine-protein kinase.	Dedicator of cytokinesis 5; Belongs to the DOCK family.	0.484
ABL1	ENSMNEP00000004647	ENSMNEP00000007383	ENSMNEP00000004647	Tyrosine-protein kinase.	Uncharacterized protein.	0.425
ABL1	ENSMNEP00000011554	ENSMNEP00000007383	ENSMNEP00000011554	Tyrosine-protein kinase.	Uncharacterized protein.	0.425
ABL1	ENSMNEP00000029022	ENSMNEP00000007383	ENSMNEP00000029022	Tyrosine-protein kinase.	Uncharacterized protein.	0.425
ABL1	ENSMNEP00000045127	ENSMNEP00000007383	ENSMNEP00000045127	Tyrosine-protein kinase.	Uncharacterized protein.	0.425
ABL1	RAC1	ENSMNEP00000007383	ENSMNEP00000031265	Tyrosine-protein kinase.	Rac family small GTPase 1.	0.886
ABL1	RAC3	ENSMNEP00000007383	ENSMNEP00000008005	Tyrosine-protein kinase.	Rac family small GTPase 3.	0.927
ARHGEF7	CDC42	ENSMNEP00000031112	ENSMNEP00000021122	Rho guanine nucleotide exchange factor 7.	Uncharacterized protein.	0.909
ARHGEF7	ENSMNEP00000004647	ENSMNEP00000031112	ENSMNEP00000004647	Rho guanine nucleotide exchange factor 7.	Uncharacterized protein.	0.709
ARHGEF7	ENSMNEP00000011554	ENSMNEP00000031112	ENSMNEP00000011554	Rho guanine nucleotide exchange factor 7.	Uncharacterized protein.	0.909
ARHGEF7	ENSMNEP00000029022	ENSMNEP00000031112	ENSMNEP00000029022	Rho guanine nucleotide exchange factor 7.	Uncharacterized protein.	0.709
ARHGEF7	ENSMNEP00000045127	ENSMNEP00000031112	ENSMNEP00000045127	Rho guanine nucleotide exchange factor 7.	Uncharacterized protein.	0.909
ARHGEF7	RAC1	ENSMNEP00000031112	ENSMNEP00000031265	Rho guanine nucleotide exchange factor 7.	Rac family small GTPase 1.	0.929
ARHGEF7	RAC3	ENSMNEP00000031112	ENSMNEP00000008005	Rho guanine nucleotide exchange factor 7.	Rac family small GTPase 3.	0.956
ARPC2	CDC42	ENSMNEP00000023317	ENSMNEP00000021122	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Uncharacterized protein.	0.520
ARPC2	ENSMNEP00000004647	ENSMNEP00000023317	ENSMNEP00000004647	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Uncharacterized protein.	0.520
ARPC2	ENSMNEP00000011554	ENSMNEP00000023317	ENSMNEP00000011554	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Uncharacterized protein.	0.520