STRINGSTRING
MYO1C MYO1C ACE ACE LRRC4B LRRC4B TJP1 TJP1 NPHP1 NPHP1 WDPCP WDPCP FMN1 FMN1 COL16A1 COL16A1 RAB17 RAB17 SIX4 SIX4 PPM1F PPM1F ENSMNEP00000000829 ENSMNEP00000000829 LRRTM1 LRRTM1 BDNF BDNF RAPGEF2 RAPGEF2 NRXN1 NRXN1 SLITRK6 SLITRK6 SRPX2 SRPX2 FLRT3 FLRT3 IL1RAPL2 IL1RAPL2 SLC9A1 SLC9A1 FLRT2 FLRT2 SLITRK2 SLITRK2 GPBAR1 GPBAR1 SLITRK3 SLITRK3 LINGO2 LINGO2 GRID2 GRID2 TPBG TPBG AMIGO1 AMIGO1 WNT5A WNT5A TPBGL TPBGL LRRN1 LRRN1 FZD5 FZD5 THY1 THY1 ARHGAP6 ARHGAP6 LIMS1 LIMS1 SLITRK4 SLITRK4 ENSMNEP00000005714 ENSMNEP00000005714 DLG5 DLG5 CLDN5 CLDN5 SRC SRC MYOC MYOC AMIGO3 AMIGO3 SEMA4A SEMA4A ENSMNEP00000006921 ENSMNEP00000006921 PTEN PTEN LINGO4 LINGO4 SLITRK1 SLITRK1 NLGN2 NLGN2 ABL1 ABL1 CAMSAP3 CAMSAP3 NTN1 NTN1 EFNA5 EFNA5 WNT4 WNT4 CHRNB2 CHRNB2 SYNDIG1 SYNDIG1 IRX3 IRX3 RAPGEF1 RAPGEF1 NTRK2 NTRK2 DKK1 DKK1 BCAS3 BCAS3 PTPRA PTPRA AGT AGT SLIT1 SLIT1 ROCK1 ROCK1 HOPX HOPX FLOT1 FLOT1 SLITRK5 SLITRK5 GPC4 GPC4 EIF4G1 EIF4G1 LOC105499779 LOC105499779 HRG HRG WNT7A WNT7A TSC1 TSC1 WNT3A WNT3A SFRP1 SFRP1 SNAI1 SNAI1 NLGN1 NLGN1 IL1RAP IL1RAP ADGRB1 ADGRB1 PTPRD PTPRD LIMCH1 LIMCH1 IL1RAPL1 IL1RAPL1 TEK TEK ABI3 ABI3 MEF2C MEF2C ENSMNEP00000025369 ENSMNEP00000025369 POLDIP2 POLDIP2 LRTM2 LRTM2 GPM6B GPM6B EPHA3 EPHA3 DUSP22 DUSP22 PTK2 PTK2 CLDN1 CLDN1 STAU2 STAU2 MYCBP2 MYCBP2 ARF6 ARF6 MAP4K4 MAP4K4 F11R F11R PHLDB2 PHLDB2 ROBO2 ROBO2 MACF1 MACF1 PTPRS PTPRS EPHA7 EPHA7 CLDN19 CLDN19 DAPK3 DAPK3 VCL VCL FERMT2 FERMT2 SNAI2 SNAI2 ADGRB3 ADGRB3 S100A10 S100A10 SEMA4D SEMA4D SMAD3 SMAD3 NTNG2 NTNG2 SLK SLK TBX5 TBX5 LHFPL4 LHFPL4 EPB41L5 EPB41L5 GHSR GHSR LRRTM2 LRRTM2 RAP1A RAP1A VSTM5 VSTM5 APP APP SETD5 SETD5 EPHB1 EPHB1 MUSK MUSK ENSMNEP00000044937 ENSMNEP00000044937 CAV1 CAV1 DMTN DMTN CLASP1 CLASP1 PTPRJ PTPRJ NPHP4 NPHP4 ROCK2 ROCK2 GHRL GHRL NTRK1 NTRK1 CNTNAP2 CNTNAP2 PEAK1 PEAK1 ITGB1BP1 ITGB1BP1 EPHA2 EPHA2 KDR KDR ADNP ADNP ENSMNEP00000039571 ENSMNEP00000039571 THBS1 THBS1 LRRTM3 LRRTM3 LRRC24 LRRC24 EPHB3 EPHB3 EPHB2 EPHB2 CLSTN1 CLSTN1 CBLN2 CBLN2 VEGFA VEGFA ENSMNEP00000035777 ENSMNEP00000035777 IL17A IL17A SDC4 SDC4 RAP1B RAP1B COLQ COLQ CRB3 CRB3 OXT OXT LRFN3 LRFN3 NECTIN1 NECTIN1 RCC2 RCC2 NPTX1 NPTX1 IKBKB IKBKB IL1B IL1B THBS2 THBS2 CLASP2 CLASP2 LDB1 LDB1 LRFN5 LRFN5 CUX2 CUX2 LRRTM4 LRRTM4 LRFN4 LRFN4 EEF2K EEF2K CBLN1 CBLN1 AGRN AGRN TLN1 TLN1 CORO1C CORO1C VPS35 VPS35 MDGA1 MDGA1 ACVRL1 ACVRL1 ACE2 ACE2 NRP1 NRP1 CLSTN2 CLSTN2 TNF TNF CLDN3 CLDN3 DLC1 DLC1 PDLIM5 PDLIM5 LRFN1 LRFN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (968 aa)
ACEAngiotensin-converting enzyme. (1160 aa)
LRRC4BLeucine rich repeat containing 4B. (713 aa)
TJP1Tight junction protein 1. (1743 aa)
NPHP1Nephrocystin 1. (717 aa)
WDPCPWD repeat containing planar cell polarity effector. (731 aa)
FMN1Formin 1. (1398 aa)
COL16A1Collagen type XVI alpha 1 chain. (1604 aa)
RAB17RAB17, member RAS oncogene family. (212 aa)
SIX4SIX homeobox 4. (772 aa)
PPM1FProtein phosphatase, Mg2+/Mn2+ dependent 1F. (455 aa)
ENSMNEP00000000829Uncharacterized protein. (278 aa)
LRRTM1Leucine rich repeat transmembrane neuronal 1. (522 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (312 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1701 aa)
NRXN1Neurexin 1. (1507 aa)
SLITRK6SLIT and NTRK like family member 6. (841 aa)
SRPX2Sushi repeat containing protein X-linked 2. (465 aa)
FLRT3Fibronectin leucine rich transmembrane protein 3. (649 aa)
IL1RAPL2Interleukin 1 receptor accessory protein like 2. (686 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa)
FLRT2Fibronectin leucine rich transmembrane protein 2. (660 aa)
SLITRK2SLIT and NTRK like family member 2. (845 aa)
GPBAR1G protein-coupled bile acid receptor 1. (330 aa)
SLITRK3SLIT and NTRK like family member 3. (979 aa)
LINGO2Leucine rich repeat and Ig domain containing 2. (606 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (1007 aa)
TPBGTrophoblast glycoprotein. (420 aa)
AMIGO1Adhesion molecule with Ig like domain 1. (493 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (419 aa)
TPBGLTrophoblast glycoprotein like. (384 aa)
LRRN1Leucine rich repeat neuronal 1. (716 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
THY1Thy-1 cell surface antigen. (161 aa)
ARHGAP6Rho GTPase activating protein 6. (977 aa)
LIMS1LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (398 aa)
SLITRK4SLIT and NTRK like family member 4. (837 aa)
ENSMNEP00000005714Uncharacterized protein. (462 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1919 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
SRCTyrosine-protein kinase. (644 aa)
MYOCMyocilin. (491 aa)
AMIGO3Adhesion molecule with Ig like domain 3. (504 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (760 aa)
ENSMNEP00000006921Uncharacterized protein. (522 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
LINGO4Leucine rich repeat and Ig domain containing 4. (593 aa)
SLITRK1SLIT and NTRK like family member 1. (696 aa)
NLGN2Neuroligin 2. (849 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
CAMSAP3Calmodulin regulated spectrin associated protein family member 3. (1226 aa)
NTN1Netrin 1. (604 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
CHRNB2Cholinergic receptor nicotinic beta 2 subunit. (502 aa)
SYNDIG1Synapse differentiation inducing 1. (258 aa)
IRX3Iroquois homeobox 3. (501 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1265 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
BCAS3BCAS3 microtubule associated cell migration factor. (922 aa)
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (804 aa)
AGTAngiotensinogen; Belongs to the serpin family. (485 aa)
SLIT1Slit guidance ligand 1. (1534 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
HOPXHOP homeobox. (112 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
SLITRK5SLIT and NTRK like family member 5. (958 aa)
GPC4Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1604 aa)
LOC105499779Arm_2 domain-containing protein. (547 aa)
HRGHistidine rich glycoprotein. (526 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
TSC1TSC complex subunit 1. (1138 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
NLGN1Neuroligin 1. (823 aa)
IL1RAPInterleukin 1 receptor accessory protein. (687 aa)
ADGRB1Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1566 aa)
PTPRDProtein tyrosine phosphatase receptor type D. (1912 aa)
LIMCH1LIM and calponin homology domains 1. (1626 aa)
IL1RAPL1Interleukin 1 receptor accessory protein like 1. (437 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
ABI3ABI family member 3. (366 aa)
MEF2CMyocyte enhancer factor 2C. (486 aa)
ENSMNEP00000025369Uncharacterized protein. (129 aa)
POLDIP2DNA polymerase delta interacting protein 2. (408 aa)
LRTM2Leucine rich repeats and transmembrane domains 2. (370 aa)
GPM6BGlycoprotein M6B. (305 aa)
EPHA3EPH receptor A3. (984 aa)
DUSP22Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1054 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
STAU2Staufen double-stranded RNA binding protein 2. (538 aa)
MYCBP2MYC binding protein 2. (4710 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (148 aa)
MAP4K4Mitogen-activated protein kinase kinase kinase kinase 4. (1326 aa)
F11RF11 receptor. (328 aa)
PHLDB2Pleckstrin homology like domain family B member 2. (1372 aa)
ROBO2Roundabout guidance receptor 2. (1439 aa)
MACF1Microtubule actin crosslinking factor 1. (7594 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1911 aa)
EPHA7EPH receptor A7. (998 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
DAPK3Death associated protein kinase 3. (429 aa)
VCLVinculin. (1134 aa)
FERMT2Fermitin family member 2. (689 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
ADGRB3Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family. (1522 aa)
S100A10S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
NTNG2Netrin G2. (530 aa)
SLKSTE20 like kinase. (1236 aa)
TBX5T-box transcription factor 5. (518 aa)
LHFPL4LHFPL tetraspan subfamily member 4. (247 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (733 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
LRRTM2Leucine rich repeat transmembrane neuronal 2. (516 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
VSTM5V-set and transmembrane domain containing 5. (200 aa)
APPAmyloid beta precursor protein. (770 aa)
SETD5SET domain containing 5. (1461 aa)
EPHB1EPH receptor B1. (984 aa)
MUSKMuscle associated receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. (737 aa)
ENSMNEP00000044937Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (297 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
DMTNDematin actin binding protein. (412 aa)
CLASP1Cytoplasmic linker associated protein 1. (1533 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1340 aa)
NPHP4Nephrocystin 4. (1426 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1474 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
CNTNAP2Contactin associated protein like 2. (1331 aa)
PEAK1Pseudopodium enriched atypical kinase 1. (1746 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
EPHA2EPH receptor A2. (976 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
ADNPActivity dependent neuroprotector homeobox. (1103 aa)
ENSMNEP00000039571Uncharacterized protein. (136 aa)
THBS1Thrombospondin 1. (1173 aa)
LRRTM3Leucine rich repeat transmembrane neuronal 3. (581 aa)
LRRC24Leucine rich repeat containing 24. (543 aa)
EPHB3EPH receptor B3. (1008 aa)
EPHB2EPH receptor B2. (1063 aa)
CLSTN1Calsyntenin 1. (1037 aa)
CBLN2Cerebellin 2 precursor. (224 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (452 aa)
ENSMNEP00000035777Apolipoprotein D. (167 aa)
IL17AInterleukin 17A. (155 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (194 aa)
RAP1BUncharacterized protein. (137 aa)
COLQCollagen like tail subunit of asymmetric acetylcholinesterase. (458 aa)
CRB3Crumbs cell polarity complex component 3. (123 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (125 aa)
LRFN3Leucine rich repeat and fibronectin type III domain containing 3. (628 aa)
NECTIN1Nectin cell adhesion molecule 1. (519 aa)
RCC2Regulator of chromosome condensation 2. (508 aa)
NPTX1Neuronal pentraxin 1. (432 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
THBS2Thrombospondin 2. (1172 aa)
CLASP2Uncharacterized protein. (1514 aa)
LDB1LIM domain binding 1. (411 aa)
LRFN5Leucine rich repeat and fibronectin type III domain containing 5. (724 aa)
CUX2Cut like homeobox 2. (1453 aa)
LRRTM4Leucine rich repeat transmembrane neuronal 4. (591 aa)
LRFN4Leucine rich repeat and fibronectin type III domain containing 4. (635 aa)
EEF2KEukaryotic elongation factor 2 kinase. (713 aa)
CBLN1Cerebellin 1 precursor. (193 aa)
AGRNAgrin. (2041 aa)
TLN1Talin 1. (2556 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (524 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
MDGA1MAM domain containing glycosylphosphatidylinositol anchor 1. (955 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (528 aa)
ACE2Angiotensin-converting enzyme. (805 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (925 aa)
CLSTN2Calsyntenin 2. (955 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
DLC1DLC1 Rho GTPase activating protein. (1528 aa)
PDLIM5PDZ and LIM domain 5. (616 aa)
LRFN1Leucine rich repeat and fibronectin type III domain containing 1. (767 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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