STRINGSTRING
DMTN DMTN WNT5A WNT5A ARHGAP6 ARHGAP6 SRC SRC PTEN PTEN DKK1 DKK1 BCAS3 BCAS3 SLIT1 SLIT1 ACE ACE EPHA7 EPHA7 ROBO2 ROBO2 PHLDB2 PHLDB2 DUSP22 DUSP22 ROCK1 ROCK1 DLC1 DLC1 TNF TNF ACVRL1 ACVRL1 CORO1C CORO1C CBLN1 CBLN1 CLASP2 CLASP2 IL1B IL1B IKBKB IKBKB RCC2 RCC2 ENSMNEP00000035777 ENSMNEP00000035777 THBS1 THBS1 ITGB1BP1 ITGB1BP1 ROCK2 ROCK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DMTNDematin actin binding protein. (412 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (419 aa)
ARHGAP6Rho GTPase activating protein 6. (977 aa)
SRCTyrosine-protein kinase. (644 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
BCAS3BCAS3 microtubule associated cell migration factor. (922 aa)
SLIT1Slit guidance ligand 1. (1534 aa)
ACEAngiotensin-converting enzyme. (1160 aa)
EPHA7EPH receptor A7. (998 aa)
ROBO2Roundabout guidance receptor 2. (1439 aa)
PHLDB2Pleckstrin homology like domain family B member 2. (1372 aa)
DUSP22Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
DLC1DLC1 Rho GTPase activating protein. (1528 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (528 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (524 aa)
CBLN1Cerebellin 1 precursor. (193 aa)
CLASP2Uncharacterized protein. (1514 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
RCC2Regulator of chromosome condensation 2. (508 aa)
ENSMNEP00000035777Apolipoprotein D. (167 aa)
THBS1Thrombospondin 1. (1173 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1474 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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