STRINGSTRING
RPTOR RPTOR MECP2 MECP2 CDC6 CDC6 NEUROG1 NEUROG1 ENSMNEP00000002161 ENSMNEP00000002161 ENSMNEP00000001503 ENSMNEP00000001503 ENSMNEP00000001266 ENSMNEP00000001266 CCNB1 CCNB1 KCNA5 KCNA5 DDR2 DDR2 CDC25A CDC25A CCND3 CCND3 EIF4G1 EIF4G1 RGCC RGCC HYAL1 HYAL1 MAD1L1 MAD1L1 AIF1 AIF1 AKT1 AKT1 PBX1 PBX1 MTA3 MTA3 FBXO5 FBXO5 CDC25C CDC25C CDCA5 CDCA5 CUL4B CUL4B SIN3A SIN3A RRM1 RRM1 HSPA2 HSPA2 FGF10 FGF10 KLHL18 KLHL18 CDK4 CDK4 ENSMNEP00000015849 ENSMNEP00000015849 DDX3X DDX3X CCND2 CCND2 ADAM17 ADAM17 MEPCE MEPCE SASS6 SASS6 CENPJ CENPJ STOX1 STOX1 DBF4B DBF4B APP APP BIRC5 BIRC5 LSM11 LSM11 TFDP1 TFDP1 CDC27 CDC27 STIL STIL PLCB1 PLCB1 CDK1 CDK1 CDC25B CDC25B DLGAP5 DLGAP5 CUL4A CUL4A LOC105475288 LOC105475288 TGFB1 TGFB1 ENSMNEP00000039662 ENSMNEP00000039662 ANAPC7 ANAPC7 MAD2L1BP MAD2L1BP RDX RDX ENSMNEP00000038452 ENSMNEP00000038452 PLRG1 PLRG1 PRAP1 PRAP1 KMT2E KMT2E TERT TERT CDT1 CDT1 MTBP MTBP CCND1 CCND1 LOC105467972 LOC105467972 RCC2 RCC2 UBE2E2 UBE2E2 RAD51B RAD51B CUL3 CUL3 RAD51C RAD51C ENSMNEP00000032397 ENSMNEP00000032397 CPSF3 CPSF3 ESPL1 ESPL1 ADAMTS1 ADAMTS1 ANAPC11 ANAPC11 RB1 RB1 BRD4 BRD4 PHOX2B PHOX2B DTL DTL ANKRD17 ANKRD17 CDC23 CDC23 ANXA1 ANXA1 TMOD3 TMOD3 RRM2 RRM2 CDC7 CDC7 CDC16 CDC16 EGFR EGFR WNT10B WNT10B NSMCE2 NSMCE2 CDK10 CDK10 LSM10 LSM10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPTORRegulatory associated protein of MTOR complex 1. (1335 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (544 aa)
NEUROG1Neurogenin 1. (237 aa)
ENSMNEP00000002161Uncharacterized protein. (142 aa)
ENSMNEP00000001503Uncharacterized protein. (73 aa)
ENSMNEP00000001266Uncharacterized protein. (234 aa)
CCNB1Cyclin B1; Belongs to the cyclin family. (433 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (605 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (873 aa)
CDC25ACell division cycle 25A. (524 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (242 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1604 aa)
RGCCRegulator of cell cycle. (137 aa)
HYAL1Hyaluronidase. (435 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (829 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PBX1PBX homeobox 1. (430 aa)
MTA3Metastasis associated 1 family member 3. (582 aa)
FBXO5F-box protein 5. (401 aa)
CDC25CCell division cycle 25C. (507 aa)
CDCA5Cell division cycle associated 5. (267 aa)
CUL4BCullin 4B; Belongs to the cullin family. (913 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (792 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (602 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
KLHL18Kelch like family member 18. (574 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (260 aa)
ENSMNEP00000015849Transcription factor. (392 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (733 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa)
ADAM17ADAM metallopeptidase domain 17. (803 aa)
MEPCEMethylphosphate capping enzyme. (689 aa)
SASS6SAS-6 centriolar assembly protein. (657 aa)
CENPJCentromere protein J. (1340 aa)
STOX1Storkhead box 1. (887 aa)
DBF4BDBF4 zinc finger B. (425 aa)
APPAmyloid beta precursor protein. (770 aa)
BIRC5Uncharacterized protein. (147 aa)
LSM11LSM11, U7 small nuclear RNA associated. (360 aa)
TFDP1Transcription factor. (410 aa)
CDC27Cell division cycle 27. (834 aa)
STILSTIL centriolar assembly protein. (1294 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
CDC25BCell division cycle 25B. (580 aa)
DLGAP5DLG associated protein 5. (851 aa)
CUL4ACullin 4A; Belongs to the cullin family. (745 aa)
LOC105475288SP-RING-type domain-containing protein. (216 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
ENSMNEP00000039662Protein kinase domain-containing protein. (539 aa)
ANAPC7Anaphase promoting complex subunit 7. (524 aa)
MAD2L1BPMAD2L1 binding protein. (293 aa)
RDXRadixin. (604 aa)
ENSMNEP00000038452Uncharacterized protein. (396 aa)
PLRG1Pleiotropic regulator 1. (514 aa)
PRAP1Uncharacterized protein. (153 aa)
KMT2ELysine methyltransferase 2E. (1859 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1132 aa)
CDT1Chromatin licensing and DNA replication factor 1. (545 aa)
MTBPMDM2 binding protein. (904 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
LOC105467972SP-RING-type domain-containing protein. (170 aa)
RCC2Regulator of chromosome condensation 2. (508 aa)
UBE2E2Ubiquitin conjugating enzyme E2 E2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
RAD51BRAD51 paralog B. (425 aa)
CUL3Cullin 3; Belongs to the cullin family. (767 aa)
RAD51CRAD51 paralog C. (379 aa)
ENSMNEP00000032397Uncharacterized protein. (298 aa)
CPSF3Cleavage and polyadenylation specific factor 3. (625 aa)
ESPL1Extra spindle pole bodies like 1, separase. (2082 aa)
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif 1. (967 aa)
ANAPC11Anaphase promoting complex subunit 11. (177 aa)
RB1RB transcriptional corepressor 1. (928 aa)
BRD4Bromodomain containing 4. (1337 aa)
PHOX2BPaired like homeobox 2B. (314 aa)
DTLDenticleless E3 ubiquitin protein ligase homolog. (730 aa)
ANKRD17Ankyrin repeat domain 17. (2603 aa)
CDC23Cell division cycle 23. (597 aa)
ANXA1Annexin. (346 aa)
TMOD3Tropomodulin 3. (352 aa)
RRM2Ribonucleotide reductase regulatory subunit M2. (439 aa)
CDC7Protein kinase domain-containing protein. (574 aa)
CDC16Cell division cycle 16. (620 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
NSMCE2Uncharacterized protein. (157 aa)
CDK10Cyclin dependent kinase 10; Belongs to the protein kinase superfamily. (361 aa)
LSM10LSM10, U7 small nuclear RNA associated. (123 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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