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ABL1 | Tyrosine-protein kinase. (1148 aa) | ||||
IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (154 aa) | ||||
EPHB6 | EPH receptor B6. (1017 aa) | ||||
CARD11 | Caspase recruitment domain family member 11. (1154 aa) | ||||
IL6 | Interleukin 6. (214 aa) | ||||
PAWR | Pro-apoptotic WT1 regulator. (342 aa) | ||||
TNFRSF14 | TNF receptor superfamily member 14. (280 aa) | ||||
CD81 | Tetraspanin. (274 aa) | ||||
IGF1 | Insulin like growth factor 1. (208 aa) | ||||
MDK | Midkine. (168 aa) | ||||
GCNT1 | Glucosaminyl (N-acetyl) transferase 1. (428 aa) | ||||
RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa) | ||||
CD27 | CD27 molecule. (260 aa) | ||||
HLA-DOA | Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa) | ||||
RHOH | Uncharacterized protein. (191 aa) | ||||
SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa) | ||||
ENSMNEP00000002245 | Ig-like domain-containing protein. (232 aa) | ||||
CHST4 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (388 aa) | ||||
SOCS5 | Suppressor of cytokine signaling 5. (536 aa) | ||||
SOX12 | Transcription factor SOX. (314 aa) | ||||
SKAP1 | Src kinase associated phosphoprotein 1. (359 aa) | ||||
IL36B | Interleukin 36 beta. (164 aa) | ||||
SOCS1 | Suppressor of cytokine signaling 1. (213 aa) | ||||
ETS1 | ETS proto-oncogene 1, transcription factor. (548 aa) | ||||
CD5 | CD5 molecule. (499 aa) | ||||
SIRPA | Uncharacterized protein. (507 aa) | ||||
HLA-DRA | Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa) | ||||
GLI3 | GLI family zinc finger 3. (1580 aa) | ||||
SOX4 | Transcription factor SOX. (475 aa) | ||||
ARID1B | AT-rich interaction domain 1B. (1539 aa) | ||||
PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) | ||||
ENSMNEP00000004521 | Ig-like domain-containing protein. (230 aa) | ||||
LOC105470433 | MHC class II antigen. (260 aa) | ||||
IRAK1 | Interleukin 1 receptor associated kinase 1. (717 aa) | ||||
PDCD1LG2 | Programmed cell death 1 ligand 2. (273 aa) | ||||
WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) | ||||
IL12RB1 | Interleukin 12 receptor subunit beta 1. (678 aa) | ||||
THY1 | Thy-1 cell surface antigen. (161 aa) | ||||
ELANE | Elastase, neutrophil expressed; Belongs to the peptidase S1 family. (263 aa) | ||||
CD44 | CD44 molecule (Indian blood group). (742 aa) | ||||
PHF10 | PHD finger protein 10. (498 aa) | ||||
SRC | Tyrosine-protein kinase. (644 aa) | ||||
CHST2 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (530 aa) | ||||
SOX13 | SRY-box transcription factor 13. (621 aa) | ||||
PRKCQ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa) | ||||
SIRPG | Signal regulatory protein gamma. (387 aa) | ||||
ENSMNEP00000007926 | Uncharacterized protein. (483 aa) | ||||
FYN | Tyrosine-protein kinase. (537 aa) | ||||
ANXA1 | Annexin. (346 aa) | ||||
CD55 | CD55 molecule (Cromer blood group). (551 aa) | ||||
CD80 | CD80 molecule. (288 aa) | ||||
LOC105474889 | AIG1-type G domain-containing protein. (307 aa) | ||||
CBFB | Core-binding factor subunit beta. (182 aa) | ||||
PNP | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa) | ||||
GLI2 | GLI family zinc finger 2. (1586 aa) | ||||
ZP4 | Zona pellucida glycoprotein 4. (538 aa) | ||||
DUSP10 | Dual specificity phosphatase 10. (488 aa) | ||||
RARA | Retinoic acid receptor alpha. (477 aa) | ||||
ICOS | Inducible T cell costimulator. (199 aa) | ||||
ICOSLG | Uncharacterized protein. (302 aa) | ||||
HLA-DPB1 | Major histocompatibility complex, class II, DP beta 1. (268 aa) | ||||
FUT7 | Fucosyltransferase 7. (342 aa) | ||||
EFNB3 | Ephrin B3; Belongs to the ephrin family. (340 aa) | ||||
SHB | SH2 domain containing adaptor protein B. (509 aa) | ||||
NFKBID | NFKB inhibitor delta. (469 aa) | ||||
ENSMNEP00000012002 | TNF receptor-associated factor. (457 aa) | ||||
PTPN22 | Protein tyrosine phosphatase non-receptor type 22. (813 aa) | ||||
NCKAP1L | NCK associated protein 1 like. (1134 aa) | ||||
ENSMNEP00000012406 | Uncharacterized protein. (72 aa) | ||||
VSIR | V-set immunoregulatory receptor. (311 aa) | ||||
PTPRC | Protein tyrosine phosphatase receptor type C. (1310 aa) | ||||
CCR7 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa) | ||||
ENSMNEP00000013168 | Ribosomal_S3_C domain-containing protein. (225 aa) | ||||
IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) | ||||
ITGB2 | Integrin beta. (921 aa) | ||||
CD6 | CD6 molecule. (699 aa) | ||||
IL1RL2 | Interleukin 1 receptor like 2. (562 aa) | ||||
IL2RG | Fibronectin type-III domain-containing protein. (369 aa) | ||||
IL4I1 | Amine oxidase. (589 aa) | ||||
JAK2 | Tyrosine-protein kinase. (1139 aa) | ||||
SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1677 aa) | ||||
IL7R | Interleukin 7 receptor. (459 aa) | ||||
TNFSF11 | Tumor necrosis factor ligand superfamily member. (317 aa) | ||||
ENSMNEP00000015304 | Uncharacterized protein. (358 aa) | ||||
CD86 | CD86 molecule. (329 aa) | ||||
TNFSF13B | TNF superfamily member 13b; Belongs to the tumor necrosis factor family. (285 aa) | ||||
RPS3 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (284 aa) | ||||
AP3D1 | Adaptor related protein complex 3 subunit delta 1. (1325 aa) | ||||
CD70 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (316 aa) | ||||
ADA | Adenosine deaminase. (449 aa) | ||||
TNFSF9 | TNF superfamily member 9; Belongs to the tumor necrosis factor family. (251 aa) | ||||
ZBTB1 | Zinc finger and BTB domain containing 1. (644 aa) | ||||
IL4R | Interleukin 4 receptor. (825 aa) | ||||
STAT5B | Signal transducer and activator of transcription. (783 aa) | ||||
IL12RB2 | Interleukin 12 receptor subunit beta 2. (842 aa) | ||||
SELE | Selectin E. (612 aa) | ||||
ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (945 aa) | ||||
SIRPD | Signal regulatory protein delta. (198 aa) | ||||
MAP3K8 | Mitogen-activated protein kinase kinase kinase 8. (572 aa) | ||||
HLA-DMA | Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (290 aa) | ||||
RASGRP1 | RAS guanyl releasing protein 1. (832 aa) | ||||
PBRM1 | Polybromo 1. (1709 aa) | ||||
SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (508 aa) | ||||
AGER | Advanced glycosylation end-product specific receptor. (414 aa) | ||||
CD209 | CD209 antigen; Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response. Probably recognizes in a calcium- dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens (By similarity). (413 aa) | ||||
ARID2 | AT-rich interaction domain 2. (1836 aa) | ||||
CD3E | CD3e molecule. (198 aa) | ||||
CCDC88B | Coiled-coil domain containing 88B. (1476 aa) | ||||
DNAJA3 | DnaJ heat shock protein family (Hsp40) member A3. (480 aa) | ||||
CD28 | CD28 molecule. (220 aa) | ||||
VAV1 | Vav guanine nucleotide exchange factor 1. (846 aa) | ||||
SIRPB1 | Uncharacterized protein. (422 aa) | ||||
LOC105470432 | Ig-like domain-containing protein; Belongs to the MHC class II family. (260 aa) | ||||
PIK3R6 | Phosphoinositide-3-kinase regulatory subunit 6. (867 aa) | ||||
SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa) | ||||
IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
CD24 | Uncharacterized protein. (127 aa) | ||||
FCHO1 | FCH domain only 1. (872 aa) | ||||
BCL6 | BCL6 transcription repressor. (708 aa) | ||||
XBP1 | BZIP domain-containing protein. (380 aa) | ||||
SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (531 aa) | ||||
ENSMNEP00000021409 | Uncharacterized protein. (123 aa) | ||||
HHLA2 | HERV-H LTR-associating 2. (426 aa) | ||||
YES1 | Tyrosine-protein kinase. (548 aa) | ||||
LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) | ||||
EFNB1 | Ephrin B1; Belongs to the ephrin family. (346 aa) | ||||
VCAM1 | Vascular cell adhesion molecule 1. (739 aa) | ||||
IL6ST | Interleukin 6 signal transducer. (942 aa) | ||||
CSK | Tyrosine-protein kinase. (450 aa) | ||||
CORO1A | Coronin; Belongs to the WD repeat coronin family. (461 aa) | ||||
KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa) | ||||
TNFSF4 | TNF superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa) | ||||
ENSMNEP00000024033 | Uncharacterized protein. (265 aa) | ||||
SART1 | Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (800 aa) | ||||
ACTL6B | Actin like 6B; Belongs to the actin family. (447 aa) | ||||
EGR3 | Early growth response 3. (387 aa) | ||||
HAS2 | Hyaluronan synthase 2. (552 aa) | ||||
NFKBIZ | NFKB inhibitor zeta. (719 aa) | ||||
ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (333 aa) | ||||
FOXP3 | Forkhead box P3. (456 aa) | ||||
NCK1 | Cytoplasmic protein. (377 aa) | ||||
IL23A | Interleukin 23 subunit alpha. (189 aa) | ||||
ENSMNEP00000025089 | Ig-like domain-containing protein. (235 aa) | ||||
SLAMF1 | Signaling lymphocytic activation molecule family member 1. (356 aa) | ||||
IGF2 | Insulin like growth factor 2. (236 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) | ||||
DPP4 | Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (766 aa) | ||||
CD74 | CD74 molecule. (294 aa) | ||||
ABL2 | Tyrosine-protein kinase. (1182 aa) | ||||
AIF1 | Allograft inflammatory factor 1. (147 aa) | ||||
LCK | Tyrosine-protein kinase. (540 aa) | ||||
HLX | H2.0 like homeobox. (495 aa) | ||||
PPP3CA | Serine/threonine-protein phosphatase. (521 aa) | ||||
CD276 | CD276 molecule. (534 aa) | ||||
ENSMNEP00000027695 | Uncharacterized protein. (445 aa) | ||||
ZAP70 | Tyrosine-protein kinase. (619 aa) | ||||
FAM49B | Family with sequence similarity 49 member B. (365 aa) | ||||
LOC105496925 | Rho-related GTP-binding protein RhoH. (191 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (548 aa) | ||||
SYK | Tyrosine-protein kinase. (629 aa) | ||||
ZBTB16 | Zinc finger and BTB domain containing 16. (673 aa) | ||||
PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa) | ||||
FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) | ||||
TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) | ||||
RUNX3 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (429 aa) | ||||
EFNB2 | Ephrin B2; Belongs to the ephrin family. (336 aa) | ||||
PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa) | ||||
HLA-DQA1 | Major histocompatibility complex, class II, DQ alpha 1; Belongs to the MHC class II family. (267 aa) | ||||
IL7 | Interleukin 7. (184 aa) | ||||
TYK2 | Tyrosine-protein kinase. (1190 aa) | ||||
NR4A3 | Nuclear receptor subfamily 4 group A member 3. (637 aa) | ||||
PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) | ||||
NCK2 | Cytoplasmic protein. (382 aa) | ||||
CD40LG | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] (261 aa) | ||||
TFRC | Transferrin receptor. (764 aa) | ||||
ARID1A | AT-rich interaction domain 1A. (2290 aa) | ||||
IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa) | ||||
ENSMNEP00000033549 | Uncharacterized protein. (168 aa) | ||||
IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) | ||||
IGFBP2 | Insulin like growth factor binding protein 2. (326 aa) | ||||
LGALS1 | Galectin. (135 aa) | ||||
ALOX5 | Arachidonate 5-lipoxygenase. (674 aa) | ||||
JAK3 | Tyrosine-protein kinase. (1088 aa) | ||||
BTN2A2 | Uncharacterized protein. (519 aa) | ||||
HLA-DPA1 | Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa) | ||||
SELP | Selectin P. (830 aa) | ||||
MALT1 | MALT1 paracaspase. (824 aa) | ||||
NFAT5 | Nuclear factor of activated T cells 5. (1548 aa) | ||||
TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) | ||||
GPAM | Glycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa) | ||||
BCL10 | BCL10 immune signaling adaptor. (233 aa) | ||||
HAVCR2 | Hepatitis A virus cellular receptor 2. (294 aa) | ||||
IL23R | Interleukin 23 receptor. (576 aa) | ||||
PYCARD | PYD and CARD domain containing. (195 aa) | ||||
ENSMNEP00000036565 | HMG box domain-containing protein. (177 aa) | ||||
AMBRA1 | Autophagy and beclin 1 regulator 1. (1298 aa) | ||||
TESPA1 | Thymocyte expressed, positive selection associated 1. (521 aa) | ||||
ADAM8 | ADAM metallopeptidase domain 8. (824 aa) | ||||
TMIGD2 | Transmembrane and immunoglobulin domain containing 2. (170 aa) | ||||
SPTA1 | Spectrin alpha, erythrocytic 1. (2420 aa) | ||||
LYN | Tyrosine-protein kinase. (512 aa) | ||||
TNFSF14 | TNF superfamily member 14; Belongs to the tumor necrosis factor family. (240 aa) | ||||
ENSMNEP00000037627 | Uncharacterized protein. (339 aa) | ||||
KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa) | ||||
ZMIZ1 | Zinc finger MIZ-type containing 1. (1073 aa) | ||||
SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1583 aa) | ||||
RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa) | ||||
MYB | MYB proto-oncogene, transcription factor. (761 aa) | ||||
VNN1 | Vanin 1. (513 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) | ||||
SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (462 aa) | ||||
RHOA | Ras homolog family member A. (193 aa) | ||||
ZBTB7B | Zinc finger and BTB domain containing 7B. (573 aa) | ||||
ENSMNEP00000038649 | Ig-like domain-containing protein. (235 aa) | ||||
CD83 | CD83 molecule. (205 aa) | ||||
IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa) | ||||
Mane-DRB1 | MHC class II protein. (266 aa) | ||||
GP1BA | Glycoprotein Ib platelet subunit alpha. (613 aa) | ||||
DOCK8 | Dedicator of cytokinesis 8; Belongs to the DOCK family. (2096 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa) | ||||
IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) | ||||
CD4 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa) | ||||
TNFRSF13C | TNF receptor superfamily member 13C. (172 aa) | ||||
ENSMNEP00000040701 | Uncharacterized protein. (164 aa) | ||||
CD160 | CD160 molecule. (181 aa) | ||||
AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa) | ||||
LEF1 | Lymphoid enhancer binding factor 1. (399 aa) | ||||
HLA-DOB | Major histocompatibility complex, class II, DO beta. (285 aa) | ||||
RASAL3 | RAS protein activator like 3. (1011 aa) | ||||
SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1105 aa) | ||||
ITGA4 | Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa) | ||||
VTCN1 | V-set domain containing T cell activation inhibitor 1. (285 aa) | ||||
NLRP3 | NLR family pyrin domain containing 3. (1035 aa) | ||||
FLOT2 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (505 aa) | ||||
IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa) | ||||
CD274 | CD274 molecule. (318 aa) | ||||
SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1268 aa) | ||||
LOC105474413 | Ig-like domain-containing protein. (295 aa) | ||||
DHPS | Uncharacterized protein. (369 aa) | ||||
SLC7A1 | Solute carrier family 7 member 1. (629 aa) | ||||
GATA3 | GATA binding protein 3. (444 aa) | ||||
LOC105474426 | Ig-like domain-containing protein. (263 aa) | ||||
IL27RA | Interleukin 27 receptor subunit alpha. (636 aa) | ||||
BAD | BCL2 associated agonist of cell death. (167 aa) | ||||
SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa) | ||||
CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) | ||||
RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa) | ||||
CD1D | CD1d molecule. (337 aa) | ||||
CCL19 | C-C motif chemokine. (123 aa) |