STRINGSTRING
ABL1 ABL1 IL2 IL2 EPHB6 EPHB6 CARD11 CARD11 IL6 IL6 PAWR PAWR TNFRSF14 TNFRSF14 CD81 CD81 IGF1 IGF1 MDK MDK GCNT1 GCNT1 RAG1 RAG1 CD27 CD27 HLA-DOA HLA-DOA RHOH RHOH SMARCE1 SMARCE1 ENSMNEP00000002245 ENSMNEP00000002245 CHST4 CHST4 SOCS5 SOCS5 SOX12 SOX12 SKAP1 SKAP1 IL36B IL36B SOCS1 SOCS1 ETS1 ETS1 CD5 CD5 SIRPA SIRPA HLA-DRA HLA-DRA GLI3 GLI3 SOX4 SOX4 ARID1B ARID1B PTPN11 PTPN11 ENSMNEP00000004521 ENSMNEP00000004521 LOC105470433 LOC105470433 IRAK1 IRAK1 PDCD1LG2 PDCD1LG2 WNT10B WNT10B IL12RB1 IL12RB1 THY1 THY1 ELANE ELANE CD44 CD44 PHF10 PHF10 SRC SRC CHST2 CHST2 SOX13 SOX13 PRKCQ PRKCQ SIRPG SIRPG ENSMNEP00000007926 ENSMNEP00000007926 FYN FYN ANXA1 ANXA1 CD55 CD55 CD80 CD80 LOC105474889 LOC105474889 CBFB CBFB PNP PNP GLI2 GLI2 ZP4 ZP4 DUSP10 DUSP10 RARA RARA ICOS ICOS ICOSLG ICOSLG HLA-DPB1 HLA-DPB1 FUT7 FUT7 EFNB3 EFNB3 SHB SHB NFKBID NFKBID ENSMNEP00000012002 ENSMNEP00000012002 PTPN22 PTPN22 NCKAP1L NCKAP1L ENSMNEP00000012406 ENSMNEP00000012406 VSIR VSIR PTPRC PTPRC CCR7 CCR7 ENSMNEP00000013168 ENSMNEP00000013168 IL21 IL21 ITGB2 ITGB2 CD6 CD6 IL1RL2 IL1RL2 IL2RG IL2RG IL4I1 IL4I1 JAK2 JAK2 SMARCA4 SMARCA4 IL7R IL7R TNFSF11 TNFSF11 ENSMNEP00000015304 ENSMNEP00000015304 CD86 CD86 TNFSF13B TNFSF13B RPS3 RPS3 AP3D1 AP3D1 CD70 CD70 ADA ADA TNFSF9 TNFSF9 ZBTB1 ZBTB1 IL4R IL4R STAT5B STAT5B IL12RB2 IL12RB2 SELE SELE ITPKB ITPKB SIRPD SIRPD MAP3K8 MAP3K8 HLA-DMA HLA-DMA RASGRP1 RASGRP1 PBRM1 PBRM1 SMARCD3 SMARCD3 AGER AGER CD209 CD209 ARID2 ARID2 CD3E CD3E CCDC88B CCDC88B DNAJA3 DNAJA3 CD28 CD28 VAV1 VAV1 SIRPB1 SIRPB1 LOC105470432 LOC105470432 PIK3R6 PIK3R6 SMARCB1 SMARCB1 IL4 IL4 PIK3CA PIK3CA CD24 CD24 FCHO1 FCHO1 BCL6 BCL6 XBP1 XBP1 SMARCD2 SMARCD2 ENSMNEP00000021409 ENSMNEP00000021409 HHLA2 HHLA2 YES1 YES1 LEP LEP EFNB1 EFNB1 VCAM1 VCAM1 IL6ST IL6ST CSK CSK CORO1A CORO1A KAT5 KAT5 TNFSF4 TNFSF4 ENSMNEP00000024033 ENSMNEP00000024033 SART1 SART1 ACTL6B ACTL6B EGR3 EGR3 HAS2 HAS2 NFKBIZ NFKBIZ ST3GAL4 ST3GAL4 FOXP3 FOXP3 NCK1 NCK1 IL23A IL23A ENSMNEP00000025089 ENSMNEP00000025089 SLAMF1 SLAMF1 IGF2 IGF2 AKT1 AKT1 DPP4 DPP4 CD74 CD74 ABL2 ABL2 AIF1 AIF1 LCK LCK HLX HLX PPP3CA PPP3CA CD276 CD276 ENSMNEP00000027695 ENSMNEP00000027695 ZAP70 ZAP70 FAM49B FAM49B LOC105496925 LOC105496925 RELA RELA SYK SYK ZBTB16 ZBTB16 PRKCZ PRKCZ FADD FADD TNF TNF RUNX3 RUNX3 EFNB2 EFNB2 PTPN6 PTPN6 HLA-DQA1 HLA-DQA1 IL7 IL7 TYK2 TYK2 NR4A3 NR4A3 PCK1 PCK1 NCK2 NCK2 CD40LG CD40LG TFRC TFRC ARID1A ARID1A IL1B IL1B ENSMNEP00000033549 ENSMNEP00000033549 IL15 IL15 IGFBP2 IGFBP2 LGALS1 LGALS1 ALOX5 ALOX5 JAK3 JAK3 BTN2A2 BTN2A2 HLA-DPA1 HLA-DPA1 SELP SELP MALT1 MALT1 NFAT5 NFAT5 TGFBR2 TGFBR2 GPAM GPAM BCL10 BCL10 HAVCR2 HAVCR2 IL23R IL23R PYCARD PYCARD ENSMNEP00000036565 ENSMNEP00000036565 AMBRA1 AMBRA1 TESPA1 TESPA1 ADAM8 ADAM8 TMIGD2 TMIGD2 SPTA1 SPTA1 LYN LYN TNFSF14 TNFSF14 ENSMNEP00000037627 ENSMNEP00000037627 KITLG KITLG ZMIZ1 ZMIZ1 SMARCA2 SMARCA2 RIPK2 RIPK2 MYB MYB VNN1 VNN1 TRAF6 TRAF6 SHH SHH RHOA RHOA ZBTB7B ZBTB7B ENSMNEP00000038649 ENSMNEP00000038649 CD83 CD83 IHH IHH Mane-DRB1 Mane-DRB1 GP1BA GP1BA DOCK8 DOCK8 TGFB1 TGFB1 IL18 IL18 CD4 CD4 TNFRSF13C TNFRSF13C ENSMNEP00000040701 ENSMNEP00000040701 CD160 CD160 AP3B1 AP3B1 LEF1 LEF1 HLA-DOB HLA-DOB RASAL3 RASAL3 SMARCC1 SMARCC1 ITGA4 ITGA4 VTCN1 VTCN1 NLRP3 NLRP3 FLOT2 FLOT2 IL12A IL12A CD274 CD274 SMARCC2 SMARCC2 LOC105474413 LOC105474413 DHPS DHPS SLC7A1 SLC7A1 GATA3 GATA3 LOC105474426 LOC105474426 IL27RA IL27RA BAD BAD SMARCD1 SMARCD1 CAV1 CAV1 RUNX1 RUNX1 IFNG IFNG CD1D CD1D CCL19 CCL19
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABL1Tyrosine-protein kinase. (1148 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (154 aa)
EPHB6EPH receptor B6. (1017 aa)
CARD11Caspase recruitment domain family member 11. (1154 aa)
IL6Interleukin 6. (214 aa)
PAWRPro-apoptotic WT1 regulator. (342 aa)
TNFRSF14TNF receptor superfamily member 14. (280 aa)
CD81Tetraspanin. (274 aa)
IGF1Insulin like growth factor 1. (208 aa)
MDKMidkine. (168 aa)
GCNT1Glucosaminyl (N-acetyl) transferase 1. (428 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa)
CD27CD27 molecule. (260 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa)
RHOHUncharacterized protein. (191 aa)
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa)
ENSMNEP00000002245Ig-like domain-containing protein. (232 aa)
CHST4Sulfotransferase; Belongs to the sulfotransferase 1 family. (388 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
SOX12Transcription factor SOX. (314 aa)
SKAP1Src kinase associated phosphoprotein 1. (359 aa)
IL36BInterleukin 36 beta. (164 aa)
SOCS1Suppressor of cytokine signaling 1. (213 aa)
ETS1ETS proto-oncogene 1, transcription factor. (548 aa)
CD5CD5 molecule. (499 aa)
SIRPAUncharacterized protein. (507 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
GLI3GLI family zinc finger 3. (1580 aa)
SOX4Transcription factor SOX. (475 aa)
ARID1BAT-rich interaction domain 1B. (1539 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
ENSMNEP00000004521Ig-like domain-containing protein. (230 aa)
LOC105470433MHC class II antigen. (260 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (717 aa)
PDCD1LG2Programmed cell death 1 ligand 2. (273 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
IL12RB1Interleukin 12 receptor subunit beta 1. (678 aa)
THY1Thy-1 cell surface antigen. (161 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (263 aa)
CD44CD44 molecule (Indian blood group). (742 aa)
PHF10PHD finger protein 10. (498 aa)
SRCTyrosine-protein kinase. (644 aa)
CHST2Sulfotransferase; Belongs to the sulfotransferase 1 family. (530 aa)
SOX13SRY-box transcription factor 13. (621 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
SIRPGSignal regulatory protein gamma. (387 aa)
ENSMNEP00000007926Uncharacterized protein. (483 aa)
FYNTyrosine-protein kinase. (537 aa)
ANXA1Annexin. (346 aa)
CD55CD55 molecule (Cromer blood group). (551 aa)
CD80CD80 molecule. (288 aa)
LOC105474889AIG1-type G domain-containing protein. (307 aa)
CBFBCore-binding factor subunit beta. (182 aa)
PNPPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa)
GLI2GLI family zinc finger 2. (1586 aa)
ZP4Zona pellucida glycoprotein 4. (538 aa)
DUSP10Dual specificity phosphatase 10. (488 aa)
RARARetinoic acid receptor alpha. (477 aa)
ICOSInducible T cell costimulator. (199 aa)
ICOSLGUncharacterized protein. (302 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (268 aa)
FUT7Fucosyltransferase 7. (342 aa)
EFNB3Ephrin B3; Belongs to the ephrin family. (340 aa)
SHBSH2 domain containing adaptor protein B. (509 aa)
NFKBIDNFKB inhibitor delta. (469 aa)
ENSMNEP00000012002TNF receptor-associated factor. (457 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (813 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
ENSMNEP00000012406Uncharacterized protein. (72 aa)
VSIRV-set immunoregulatory receptor. (311 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1310 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
ENSMNEP00000013168Ribosomal_S3_C domain-containing protein. (225 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
ITGB2Integrin beta. (921 aa)
CD6CD6 molecule. (699 aa)
IL1RL2Interleukin 1 receptor like 2. (562 aa)
IL2RGFibronectin type-III domain-containing protein. (369 aa)
IL4I1Amine oxidase. (589 aa)
JAK2Tyrosine-protein kinase. (1139 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1677 aa)
IL7RInterleukin 7 receptor. (459 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
ENSMNEP00000015304Uncharacterized protein. (358 aa)
CD86CD86 molecule. (329 aa)
TNFSF13BTNF superfamily member 13b; Belongs to the tumor necrosis factor family. (285 aa)
RPS3KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (284 aa)
AP3D1Adaptor related protein complex 3 subunit delta 1. (1325 aa)
CD70TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (316 aa)
ADAAdenosine deaminase. (449 aa)
TNFSF9TNF superfamily member 9; Belongs to the tumor necrosis factor family. (251 aa)
ZBTB1Zinc finger and BTB domain containing 1. (644 aa)
IL4RInterleukin 4 receptor. (825 aa)
STAT5BSignal transducer and activator of transcription. (783 aa)
IL12RB2Interleukin 12 receptor subunit beta 2. (842 aa)
SELESelectin E. (612 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (945 aa)
SIRPDSignal regulatory protein delta. (198 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (572 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (290 aa)
RASGRP1RAS guanyl releasing protein 1. (832 aa)
PBRM1Polybromo 1. (1709 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (508 aa)
AGERAdvanced glycosylation end-product specific receptor. (414 aa)
CD209CD209 antigen; Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response. Probably recognizes in a calcium- dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens (By similarity). (413 aa)
ARID2AT-rich interaction domain 2. (1836 aa)
CD3ECD3e molecule. (198 aa)
CCDC88BCoiled-coil domain containing 88B. (1476 aa)
DNAJA3DnaJ heat shock protein family (Hsp40) member A3. (480 aa)
CD28CD28 molecule. (220 aa)
VAV1Vav guanine nucleotide exchange factor 1. (846 aa)
SIRPB1Uncharacterized protein. (422 aa)
LOC105470432Ig-like domain-containing protein; Belongs to the MHC class II family. (260 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (867 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CD24Uncharacterized protein. (127 aa)
FCHO1FCH domain only 1. (872 aa)
BCL6BCL6 transcription repressor. (708 aa)
XBP1BZIP domain-containing protein. (380 aa)
SMARCD2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (531 aa)
ENSMNEP00000021409Uncharacterized protein. (123 aa)
HHLA2HERV-H LTR-associating 2. (426 aa)
YES1Tyrosine-protein kinase. (548 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (346 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
IL6STInterleukin 6 signal transducer. (942 aa)
CSKTyrosine-protein kinase. (450 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
TNFSF4TNF superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa)
ENSMNEP00000024033Uncharacterized protein. (265 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (800 aa)
ACTL6BActin like 6B; Belongs to the actin family. (447 aa)
EGR3Early growth response 3. (387 aa)
HAS2Hyaluronan synthase 2. (552 aa)
NFKBIZNFKB inhibitor zeta. (719 aa)
ST3GAL4ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (333 aa)
FOXP3Forkhead box P3. (456 aa)
NCK1Cytoplasmic protein. (377 aa)
IL23AInterleukin 23 subunit alpha. (189 aa)
ENSMNEP00000025089Ig-like domain-containing protein. (235 aa)
SLAMF1Signaling lymphocytic activation molecule family member 1. (356 aa)
IGF2Insulin like growth factor 2. (236 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (766 aa)
CD74CD74 molecule. (294 aa)
ABL2Tyrosine-protein kinase. (1182 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
LCKTyrosine-protein kinase. (540 aa)
HLXH2.0 like homeobox. (495 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
CD276CD276 molecule. (534 aa)
ENSMNEP00000027695Uncharacterized protein. (445 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
FAM49BFamily with sequence similarity 49 member B. (365 aa)
LOC105496925Rho-related GTP-binding protein RhoH. (191 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
SYKTyrosine-protein kinase. (629 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (429 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (336 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
HLA-DQA1Major histocompatibility complex, class II, DQ alpha 1; Belongs to the MHC class II family. (267 aa)
IL7Interleukin 7. (184 aa)
TYK2Tyrosine-protein kinase. (1190 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (637 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
NCK2Cytoplasmic protein. (382 aa)
CD40LGCD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] (261 aa)
TFRCTransferrin receptor. (764 aa)
ARID1AAT-rich interaction domain 1A. (2290 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
ENSMNEP00000033549Uncharacterized protein. (168 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
IGFBP2Insulin like growth factor binding protein 2. (326 aa)
LGALS1Galectin. (135 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
JAK3Tyrosine-protein kinase. (1088 aa)
BTN2A2Uncharacterized protein. (519 aa)
HLA-DPA1Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa)
SELPSelectin P. (830 aa)
MALT1MALT1 paracaspase. (824 aa)
NFAT5Nuclear factor of activated T cells 5. (1548 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
BCL10BCL10 immune signaling adaptor. (233 aa)
HAVCR2Hepatitis A virus cellular receptor 2. (294 aa)
IL23RInterleukin 23 receptor. (576 aa)
PYCARDPYD and CARD domain containing. (195 aa)
ENSMNEP00000036565HMG box domain-containing protein. (177 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1298 aa)
TESPA1Thymocyte expressed, positive selection associated 1. (521 aa)
ADAM8ADAM metallopeptidase domain 8. (824 aa)
TMIGD2Transmembrane and immunoglobulin domain containing 2. (170 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2420 aa)
LYNTyrosine-protein kinase. (512 aa)
TNFSF14TNF superfamily member 14; Belongs to the tumor necrosis factor family. (240 aa)
ENSMNEP00000037627Uncharacterized protein. (339 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1073 aa)
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1583 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
MYBMYB proto-oncogene, transcription factor. (761 aa)
VNN1Vanin 1. (513 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (462 aa)
RHOARas homolog family member A. (193 aa)
ZBTB7BZinc finger and BTB domain containing 7B. (573 aa)
ENSMNEP00000038649Ig-like domain-containing protein. (235 aa)
CD83CD83 molecule. (205 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
Mane-DRB1MHC class II protein. (266 aa)
GP1BAGlycoprotein Ib platelet subunit alpha. (613 aa)
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2096 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa)
TNFRSF13CTNF receptor superfamily member 13C. (172 aa)
ENSMNEP00000040701Uncharacterized protein. (164 aa)
CD160CD160 molecule. (181 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
HLA-DOBMajor histocompatibility complex, class II, DO beta. (285 aa)
RASAL3RAS protein activator like 3. (1011 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1105 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (285 aa)
NLRP3NLR family pyrin domain containing 3. (1035 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (505 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
CD274CD274 molecule. (318 aa)
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1268 aa)
LOC105474413Ig-like domain-containing protein. (295 aa)
DHPSUncharacterized protein. (369 aa)
SLC7A1Solute carrier family 7 member 1. (629 aa)
GATA3GATA binding protein 3. (444 aa)
LOC105474426Ig-like domain-containing protein. (263 aa)
IL27RAInterleukin 27 receptor subunit alpha. (636 aa)
BADBCL2 associated agonist of cell death. (167 aa)
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa)
CD1DCD1d molecule. (337 aa)
CCL19C-C motif chemokine. (123 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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