STRINGSTRING
NEUROD1 NEUROD1 ATOH1 ATOH1 MST1 MST1 MAPK7 MAPK7 TERT TERT ANGPT1 ANGPT1 IL10 IL10 CDH5 CDH5 KDR KDR NDNF NDNF SEMA5A SEMA5A AGAP2 AGAP2 GATA3 GATA3 TNIP2 TNIP2 PDPK1 PDPK1 MDK MDK NKX2-5 NKX2-5 IL13 IL13 CDKN1B CDKN1B ADAR ADAR RB1 RB1 WFS1 WFS1 NUPR1 NUPR1 PRKAA1 PRKAA1 NKX2-6 NKX2-6 GATA2 GATA2 ABL1 ABL1 NFE2L2 NFE2L2 SRSF6 SRSF6 SERPINE1 SERPINE1 BRAF BRAF TCF7L2 TCF7L2 HAND2 HAND2 SERPINB13 SERPINB13 ANGPTL4 ANGPTL4 FGG FGG IGF1R IGF1R ENSMNEP00000029572 ENSMNEP00000029572 PKHD1 PKHD1 CAST CAST GAS6 GAS6 TEK TEK FGB FGB TNFAIP3 TNFAIP3 BCL2 BCL2 FGF21 FGF21 KRIT1 KRIT1 FGA FGA PPARA PPARA BTC BTC TMF1 TMF1 RAMP2 RAMP2 PAK4 PAK4 ENSMNEP00000016378 ENSMNEP00000016378 YAP1 YAP1 PDX1 PDX1 ENSMNEP00000015875 ENSMNEP00000015875
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NEUROD1Neurogenic differentiation factor. (356 aa)
ATOH1Atonal bHLH transcription factor 1. (354 aa)
MST1Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (813 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1132 aa)
ANGPT1Angiopoietin 1. (498 aa)
IL10Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
NDNFNeuron derived neurotrophic factor. (577 aa)
SEMA5ASemaphorin 5A. (1074 aa)
AGAP2ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1192 aa)
GATA3GATA binding protein 3. (444 aa)
TNIP2TNFAIP3 interacting protein 2. (429 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (582 aa)
MDKMidkine. (168 aa)
NKX2-5NK2 homeobox 5. (324 aa)
IL13Interleukin 13. (146 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
ADARAdenosine deaminase RNA specific. (1364 aa)
RB1RB transcriptional corepressor 1. (928 aa)
WFS1Wolframin ER transmembrane glycoprotein. (890 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (100 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
NKX2-6NK2 homeobox 6. (301 aa)
GATA2GATA binding protein 2. (480 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (618 aa)
SRSF6Serine and arginine rich splicing factor 6. (343 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (379 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (763 aa)
TCF7L2Transcription factor 7 like 2. (523 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
SERPINB13Serpin family B member 13; Belongs to the serpin family. (400 aa)
ANGPTL4Angiopoietin like 4. (406 aa)
FGGFibrinogen gamma chain. (437 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
ENSMNEP00000029572annotation not available (343 aa)
PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4072 aa)
CASTCalpastatin. (796 aa)
GAS6Growth arrest specific 6. (683 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
FGBFibrinogen beta chain. (491 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
KRIT1Uncharacterized protein. (736 aa)
FGAFibrinogen alpha chain. (862 aa)
PPARAPeroxisome proliferator activated receptor alpha. (467 aa)
BTCBetacellulin. (145 aa)
TMF1TATA element modulatory factor 1. (1095 aa)
RAMP2Receptor activity modifying protein 2. (175 aa)
PAK4Non-specific serine/threonine protein kinase. (702 aa)
ENSMNEP00000016378Protein kinase domain-containing protein. (652 aa)
YAP1Yes associated protein 1. (506 aa)
PDX1Pancreatic and duodenal homeobox 1. (281 aa)
ENSMNEP00000015875CCHC NOA-type domain-containing protein. (361 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.