23 items (Macaca nemestrina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RHOA	Ras homolog family member A. (193 aa)
	ITGA4	Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
	GP1BA	Glycoprotein Ib platelet subunit alpha. (613 aa)
	IL6	Interleukin 6. (214 aa)
	PAWR	Pro-apoptotic WT1 regulator. (342 aa)
	MDK	Midkine. (168 aa)
	GCNT1	Glucosaminyl (N-acetyl) transferase 1. (428 aa)
	CHST4	Sulfotransferase; Belongs to the sulfotransferase 1 family. (388 aa)
	ETS1	ETS proto-oncogene 1, transcription factor. (548 aa)
	IRAK1	Interleukin 1 receptor associated kinase 1. (717 aa)
	ELANE	Elastase, neutrophil expressed; Belongs to the peptidase S1 family. (263 aa)
	CHST2	Sulfotransferase; Belongs to the sulfotransferase 1 family. (530 aa)
	FUT7	Fucosyltransferase 7. (342 aa)
	ENSMNEP00000012002	TNF receptor-associated factor. (457 aa)
	ITGB2	Integrin beta. (921 aa)
	SELE	Selectin E. (612 aa)
	ST3GAL4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (333 aa)
	RELA	RELA proto-oncogene, NF-kB subunit. (548 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
	ALOX5	Arachidonate 5-lipoxygenase. (674 aa)
	SELP	Selectin P. (830 aa)
	NFAT5	Nuclear factor of activated T cells 5. (1548 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMNEP00000012002	IRAK1	ENSMNEP00000012002	ENSMNEP00000004732	TNF receptor-associated factor.	Interleukin 1 receptor associated kinase 1.	0.965
ENSMNEP00000012002	RELA	ENSMNEP00000012002	ENSMNEP00000028444	TNF receptor-associated factor.	RELA proto-oncogene, NF-kB subunit.	0.495
ENSMNEP00000012002	TNF	ENSMNEP00000012002	ENSMNEP00000029202	TNF receptor-associated factor.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.663
FUT7	SELE	ENSMNEP00000011126	ENSMNEP00000017660	Fucosyltransferase 7.	Selectin E.	0.465
FUT7	SELP	ENSMNEP00000011126	ENSMNEP00000035658	Fucosyltransferase 7.	Selectin P.	0.479
FUT7	ST3GAL4	ENSMNEP00000011126	ENSMNEP00000024563	Fucosyltransferase 7.	ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family.	0.604
GP1BA	ITGB2	ENSMNEP00000039766	ENSMNEP00000013575	Glycoprotein Ib platelet subunit alpha.	Integrin beta.	0.576
GP1BA	SELE	ENSMNEP00000039766	ENSMNEP00000017660	Glycoprotein Ib platelet subunit alpha.	Selectin E.	0.432
GP1BA	SELP	ENSMNEP00000039766	ENSMNEP00000035658	Glycoprotein Ib platelet subunit alpha.	Selectin P.	0.635
IL6	IRAK1	ENSMNEP00000000727	ENSMNEP00000004732	Interleukin 6.	Interleukin 1 receptor associated kinase 1.	0.452
IL6	RELA	ENSMNEP00000000727	ENSMNEP00000028444	Interleukin 6.	RELA proto-oncogene, NF-kB subunit.	0.951
IL6	SELE	ENSMNEP00000000727	ENSMNEP00000017660	Interleukin 6.	Selectin E.	0.618
IL6	SELP	ENSMNEP00000000727	ENSMNEP00000035658	Interleukin 6.	Selectin P.	0.595
IL6	TNF	ENSMNEP00000000727	ENSMNEP00000029202	Interleukin 6.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.863
IL6	TRAF6	ENSMNEP00000000727	ENSMNEP00000038358	Interleukin 6.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.572
IRAK1	ENSMNEP00000012002	ENSMNEP00000004732	ENSMNEP00000012002	Interleukin 1 receptor associated kinase 1.	TNF receptor-associated factor.	0.965
IRAK1	IL6	ENSMNEP00000004732	ENSMNEP00000000727	Interleukin 1 receptor associated kinase 1.	Interleukin 6.	0.452
IRAK1	RELA	ENSMNEP00000004732	ENSMNEP00000028444	Interleukin 1 receptor associated kinase 1.	RELA proto-oncogene, NF-kB subunit.	0.592
IRAK1	TNF	ENSMNEP00000004732	ENSMNEP00000029202	Interleukin 1 receptor associated kinase 1.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.577
IRAK1	TRAF6	ENSMNEP00000004732	ENSMNEP00000038358	Interleukin 1 receptor associated kinase 1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.998