STRINGSTRING
ENSMNEP00000002472 ENSMNEP00000002472 SOCS5 SOCS5 RYBP RYBP ENSMNEP00000001975 ENSMNEP00000001975 UFL1 UFL1 ENSMNEP00000001314 ENSMNEP00000001314 ENSMNEP00000001309 ENSMNEP00000001309 NKD2 NKD2 ENSMNEP00000021101 ENSMNEP00000021101 HSP90AB1 HSP90AB1 XBP1 XBP1 SUFU SUFU DISC1 DISC1 ENSMNEP00000020161 ENSMNEP00000020161 TRIB2 TRIB2 EIF3H EIF3H EGF EGF CBFA2T3 CBFA2T3 SH3RF3 SH3RF3 RACK1 RACK1 GIPC3 GIPC3 PTK2B PTK2B STUB1 STUB1 GIPC2 GIPC2 ARAF ARAF WAC WAC C16orf96 C16orf96 ENSMNEP00000015675 ENSMNEP00000015675 BBS7 BBS7 KLHL40 KLHL40 ARIH1 ARIH1 FBXW8 FBXW8 ENSMNEP00000014831 ENSMNEP00000014831 MKRN2 MKRN2 RNF217 RNF217 CCAR2 CCAR2 ENSMNEP00000013458 ENSMNEP00000013458 XPO1 XPO1 RNF19A RNF19A SMURF1 SMURF1 RNF139 RNF139 SMARCC1 SMARCC1 PBK PBK ENSMNEP00000042025 ENSMNEP00000042025 PLK1 PLK1 WNT1 WNT1 ENSMNEP00000042578 ENSMNEP00000042578 RPL5 RPL5 CDK2 CDK2 DDA1 DDA1 TRIB3 TRIB3 USP14 USP14 PSMD10 PSMD10 CLU CLU ELOB ELOB N4BP1 N4BP1 PTK2 PTK2 BAG6 BAG6 STYX STYX AKT1 AKT1 VCP VCP ENSMNEP00000026506 ENSMNEP00000026506 UBE2K UBE2K PANO1 PANO1 GLMN GLMN ENSMNEP00000027434 ENSMNEP00000027434 PSEN1 PSEN1 PML PML ENSMNEP00000039996 ENSMNEP00000039996 RNF19B RNF19B ENSMNEP00000039400 ENSMNEP00000039400 LATS1 LATS1 NOP53 NOP53 GABARAP GABARAP RPS7 RPS7 PABPN1L PABPN1L GIPC1 GIPC1 CAV1 CAV1 NUB1 NUB1 ENSMNEP00000045066 ENSMNEP00000045066 CAV3 CAV3 AXIN2 AXIN2 MAGEF1 MAGEF1 HECTD1 HECTD1 ENSMNEP00000001014 ENSMNEP00000001014 DET1 DET1 ZYG11B ZYG11B ENSMNEP00000028330 ENSMNEP00000028330 UBQLN2 UBQLN2 CLUL1 CLUL1 CAMLG CAMLG RBX1 RBX1 RNF144A RNF144A ENSMNEP00000012238 ENSMNEP00000012238 PYHIN1 PYHIN1 PIAS1 PIAS1 PARK7 PARK7 DESI1 DESI1 USP5 USP5 DDRGK1 DDRGK1 ENSMNEP00000010524 ENSMNEP00000010524 GSK3A GSK3A ENSMNEP00000030578 ENSMNEP00000030578 DNAJB2 DNAJB2 HIPK2 HIPK2 TLK2 TLK2 SDCBP SDCBP PLK3 PLK3 RAD23B RAD23B ENSMNEP00000032418 ENSMNEP00000032418 FBXW9 FBXW9 SMAD7 SMAD7 CCDC22 CCDC22 ENSMNEP00000033022 ENSMNEP00000033022 UCHL5 UCHL5 GNA12 GNA12 ARIH2 ARIH2 ENSMNEP00000034131 ENSMNEP00000034131 TAF1 TAF1 ENSMNEP00000034429 ENSMNEP00000034429 RCHY1 RCHY1 FHIT FHIT BAG5 BAG5 RNF14 RNF14 USP7 USP7 OGT OGT DVL1 DVL1 MAPK9 MAPK9 HERPUD1 HERPUD1 FBXO22 FBXO22 UBQLN1 UBQLN1 AXIN1 AXIN1 ENSMNEP00000037484 ENSMNEP00000037484 PRICKLE1 PRICKLE1 COP1 COP1 SUMO1 SUMO1 IL33 IL33 ENSMNEP00000038155 ENSMNEP00000038155 RAD23A RAD23A SHH SHH LRRK2 LRRK2 SIRT6 SIRT6 TTC36 TTC36 RPL11 RPL11 TRIB1 TRIB1 DAB2 DAB2 RNF180 RNF180 AGBL4 AGBL4 SIRT2 SIRT2 FZR1 FZR1 UBQLN4 UBQLN4 UBE3A UBE3A ANKIB1 ANKIB1 UBQLN3 UBQLN3 LOC105464452 LOC105464452 NFE2L2 NFE2L2 QRICH2 QRICH2 CSNK2A2 CSNK2A2 PTEN PTEN SGTA SGTA RNF144B RNF144B HFE HFE PRKN PRKN AGTPBP1 AGTPBP1 CDC20 CDC20 ENSMNEP00000023187 ENSMNEP00000023187 GCLC GCLC ENSMNEP00000023008 ENSMNEP00000023008 TRIM39 TRIM39 FBXW7 FBXW7 CSNK1D CSNK1D ENSMNEP00000021373 ENSMNEP00000021373 ZER1 ZER1 ENSMNEP00000006277 ENSMNEP00000006277 GSK3B GSK3B COMMD1 COMMD1 UBXN1 UBXN1 WNT10B WNT10B ENSMNEP00000004624 ENSMNEP00000004624 ENSMNEP00000004611 ENSMNEP00000004611 AURKA AURKA ZYG11A ZYG11A HSPBP1 HSPBP1 SVIP SVIP CDC20B CDC20B FOXF2 FOXF2 SOCS4 SOCS4 TRIM67 TRIM67 ENSMNEP00000003442 ENSMNEP00000003442 SH3RF2 SH3RF2 ENSMNEP00000003112 ENSMNEP00000003112 MAP1A MAP1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMNEP00000002472Uncharacterized protein. (245 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
RYBPRING1 and YY1 binding protein. (223 aa)
ENSMNEP00000001975Uncharacterized protein. (235 aa)
UFL1UFM1 specific ligase 1. (793 aa)
ENSMNEP0000000131440S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (202 aa)
ENSMNEP00000001309Uncharacterized protein; Belongs to the universal ribosomal protein uL5 family. (170 aa)
NKD2NKD inhibitor of WNT signaling pathway 2. (442 aa)
ENSMNEP00000021101Zf-rbx1 domain-containing protein. (93 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (724 aa)
XBP1BZIP domain-containing protein. (380 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (526 aa)
DISC1DISC1 scaffold protein. (858 aa)
ENSMNEP00000020161Uncharacterized protein. (247 aa)
TRIB2Tribbles pseudokinase 2. (343 aa)
EIF3HEukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (366 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1166 aa)
CBFA2T3CBFA2/RUNX1 partner transcriptional co-repressor 3. (769 aa)
SH3RF3SH3 domain containing ring finger 3. (882 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
GIPC3GIPC PDZ domain containing family member 3. (312 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
GIPC2GIPC PDZ domain containing family member 2. (319 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (606 aa)
WACWW domain containing adaptor with coiled-coil. (647 aa)
C16orf96Chromosome 16 open reading frame 96. (1128 aa)
ENSMNEP00000015675Uncharacterized protein. (105 aa)
BBS7Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)
KLHL40Kelch like family member 40. (621 aa)
ARIH1Ariadne RBR E3 ubiquitin protein ligase 1. (483 aa)
FBXW8F-box and WD repeat domain containing 8. (598 aa)
ENSMNEP00000014831HATPase_c domain-containing protein. (645 aa)
MKRN2Makorin ring finger protein 2. (416 aa)
RNF217RBR-type E3 ubiquitin transferase. (542 aa)
CCAR2Cell cycle and apoptosis regulator 2. (923 aa)
ENSMNEP00000013458PDZ domain-containing protein. (259 aa)
XPO1Exportin 1. (1071 aa)
RNF19ARBR-type E3 ubiquitin transferase. (838 aa)
SMURF1SMAD specific E3 ubiquitin protein ligase 1. (641 aa)
RNF139Ring finger protein 139. (664 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1105 aa)
PBKPDZ binding kinase. (323 aa)
ENSMNEP0000004202540S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (179 aa)
PLK1Serine/threonine-protein kinase PLK. (603 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
ENSMNEP00000042578Rad60-SLD domain-containing protein. (65 aa)
RPL5Ribosomal_L18_c domain-containing protein. (276 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
DDA1DET1 and DDB1 associated 1. (166 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
USP14Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (493 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
CLUClusterin. (534 aa)
ELOBElongin B. (167 aa)
N4BP1NEDD4 binding protein 1. (896 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1054 aa)
BAG6BCL2 associated athanogene 6. (1256 aa)
STYXSerine/threonine/tyrosine interacting protein. (223 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
VCPValosin containing protein. (767 aa)
ENSMNEP00000026506Uncharacterized protein. (90 aa)
UBE2KUbiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (132 aa)
PANO1Uncharacterized protein. (185 aa)
GLMNGlomulin, FKBP associated protein. (594 aa)
ENSMNEP00000027434Uncharacterized protein. (286 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
PMLPromyelocytic leukemia. (882 aa)
ENSMNEP00000039996HECT domain-containing protein. (528 aa)
RNF19BRBR-type E3 ubiquitin transferase. (541 aa)
ENSMNEP00000039400Ubiquitin-like domain-containing protein. (104 aa)
LATS1Large tumor suppressor kinase 1. (1129 aa)
NOP53NOP53 ribosome biogenesis factor. (496 aa)
GABARAPGABA type A receptor-associated protein. (117 aa)
RPS740S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (198 aa)
PABPN1LPoly(A) binding protein nuclear 1 like, cytoplasmic. (275 aa)
GIPC1GIPC PDZ domain containing family member 1. (333 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
NUB1Negative regulator of ubiquitin like proteins 1. (649 aa)
ENSMNEP00000045066Ribosomal_L18_c domain-containing protein. (280 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
AXIN2Axin 2. (844 aa)
MAGEF1MAGE family member F1. (308 aa)
HECTD1HECT domain E3 ubiquitin protein ligase 1. (2610 aa)
ENSMNEP00000001014UBA domain-containing protein. (78 aa)
DET1Uncharacterized protein. (561 aa)
ZYG11BZyg-11 family member B, cell cycle regulator. (746 aa)
ENSMNEP00000028330Uncharacterized protein. (60 aa)
UBQLN2Ubiquilin 2. (624 aa)
CLUL1Clusterin; Belongs to the clusterin family. (518 aa)
CAMLGCalcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (296 aa)
RBX1RING-type domain-containing protein. (108 aa)
RNF144ARBR-type E3 ubiquitin transferase. (292 aa)
ENSMNEP00000012238RBR-type E3 ubiquitin transferase. (369 aa)
PYHIN1Pyrin and HIN domain family member 1. (494 aa)
PIAS1Protein inhibitor of activated STAT 1. (653 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
DESI1Desumoylating isopeptidase 1. (168 aa)
USP5Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (835 aa)
DDRGK1DDRGK domain containing 1. (342 aa)
ENSMNEP00000010524DJ-1_PfpI domain-containing protein. (186 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
ENSMNEP00000030578PDZ domain-containing protein. (262 aa)
DNAJB2DnaJ heat shock protein family (Hsp40) member B2. (324 aa)
HIPK2Homeodomain interacting protein kinase 2. (1198 aa)
TLK2Tousled like kinase 2. (750 aa)
SDCBPSyndecan binding protein. (318 aa)
PLK3Serine/threonine-protein kinase PLK. (608 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (409 aa)
ENSMNEP00000032418DJ-1_PfpI domain-containing protein. (166 aa)
FBXW9F-box and WD repeat domain containing 9. (458 aa)
SMAD7Mothers against decapentaplegic homolog. (488 aa)
CCDC22Coiled-coil domain containing 22. (627 aa)
ENSMNEP00000033022Uncharacterized protein. (77 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (368 aa)
GNA12G protein subunit alpha 12. (314 aa)
ARIH2RBR-type E3 ubiquitin transferase. (491 aa)
ENSMNEP00000034131DJ-1_PfpI domain-containing protein. (170 aa)
TAF1Transcription initiation factor TFIID subunit. (1875 aa)
ENSMNEP00000034429Uncharacterized protein. (291 aa)
RCHY1Ring finger and CHY zinc finger domain containing 1. (261 aa)
FHITBis(5'-adenosyl)-triphosphatase. (149 aa)
BAG5BCL2 associated athanogene 5. (488 aa)
RNF14RBR-type E3 ubiquitin transferase. (474 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1102 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
DVL1Dishevelled segment polarity protein 1. (690 aa)
MAPK9Mitogen-activated protein kinase 9. (354 aa)
HERPUD1Homocysteine inducible ER protein with ubiquitin like domain 1. (391 aa)
FBXO22F-box protein 22. (404 aa)
UBQLN1Ubiquilin 1. (589 aa)
AXIN1Axin 1. (867 aa)
ENSMNEP00000037484HECT domain-containing protein. (55 aa)
PRICKLE1Prickle planar cell polarity protein 1. (848 aa)
COP1COP1 E3 ubiquitin ligase. (731 aa)
SUMO1Ubiquitin-like domain-containing protein. (146 aa)
IL33Interleukin 33. (270 aa)
ENSMNEP00000038155Uncharacterized protein. (314 aa)
RAD23ARAD23 homolog A, nucleotide excision repair protein. (363 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (462 aa)
LRRK2Leucine rich repeat kinase 2. (2512 aa)
SIRT6Sirtuin 6. (356 aa)
TTC36Tetratricopeptide repeat domain 36. (189 aa)
RPL11Ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family. (178 aa)
TRIB1Tribbles pseudokinase 1. (372 aa)
DAB2DAB adaptor protein 2. (770 aa)
RNF180Ring finger protein 180. (592 aa)
AGBL4ATP/GTP binding protein like 4. (503 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
FZR1Fizzy and cell division cycle 20 related 1. (493 aa)
UBQLN4Ubiquilin 4. (601 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (877 aa)
ANKIB1RBR-type E3 ubiquitin transferase. (1089 aa)
UBQLN3Ubiquilin 3. (655 aa)
LOC105464452Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (618 aa)
QRICH2Glutamine rich 2. (1831 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (345 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
SGTASmall glutamine rich tetratricopeptide repeat containing alpha. (313 aa)
RNF144BRBR-type E3 ubiquitin transferase. (303 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (348 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
AGTPBP1ATP/GTP binding protein 1. (1193 aa)
CDC20Cell division cycle 20. (499 aa)
ENSMNEP00000023187Ubiquitin-like domain-containing protein. (550 aa)
GCLCGlutamate-cysteine ligase catalytic subunit. (637 aa)
ENSMNEP00000023008ANK_REP_REGION domain-containing protein. (159 aa)
TRIM39Tripartite motif containing 39. (518 aa)
FBXW7F-box and WD repeat domain containing 7. (707 aa)
CSNK1DCasein kinase 1 delta; Belongs to the protein kinase superfamily. (427 aa)
ENSMNEP00000021373Uncharacterized protein. (72 aa)
ZER1Zyg-11 related cell cycle regulator. (743 aa)
ENSMNEP00000006277Rad60-SLD domain-containing protein. (67 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa)
COMMD1Copper metabolism domain containing 1. (184 aa)
UBXN1UBX domain protein 1. (313 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
ENSMNEP0000000462440S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (171 aa)
ENSMNEP00000004611Ribosomal_L18_c domain-containing protein. (268 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (403 aa)
ZYG11AZyg-11 family member A, cell cycle regulator. (759 aa)
HSPBP1HSPA (Hsp70) binding protein 1. (410 aa)
SVIPSmall VCP interacting protein. (77 aa)
CDC20BCell division cycle 20B. (519 aa)
FOXF2Forkhead box F2. (447 aa)
SOCS4Suppressor of cytokine signaling 4. (440 aa)
TRIM67Tripartite motif containing 67. (782 aa)
ENSMNEP00000003442Uncharacterized protein. (81 aa)
SH3RF2SH3 domain containing ring finger 2. (729 aa)
ENSMNEP00000003112Small ubiquitin-related modifier. (113 aa)
MAP1AMicrotubule associated protein 1A. (3042 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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