STRINGSTRING
SOCS5 SOCS5 LYPD6 LYPD6 LYPD1 LYPD1 SOCS4 SOCS4 ZGPAT ZGPAT AGTR2 AGTR2 DKK4 DKK4 HFE HFE CNRIP1 CNRIP1 FST FST DKK1 DKK1 LRPAP1 LRPAP1 LY6H LY6H PXDN PXDN CBL CBL LYNX1 LYNX1 ADH7 ADH7 IGSF1 IGSF1 RAMP3 RAMP3 PPARA PPARA DKK2 DKK2 CLEC12B CLEC12B CBLB CBLB VPS25 VPS25 SLC6A9 SLC6A9 LYNX1-SLURP2 LYNX1-SLURP2 PCSK9 PCSK9 LYPD6B LYPD6B IL18BP IL18BP PSEN1 PSEN1 CHMP6 CHMP6 TNF TNF ACE2 ACE2 SPINT3 SPINT3 WFIKKN2 WFIKKN2 CRHBP CRHBP IL36RN IL36RN ZFYVE28 ZFYVE28 DKK3 DKK3 DKKL1 DKKL1 EPHB2 EPHB2 TSG101 TSG101 IL1RN IL1RN FAM72A FAM72A GPRC5A GPRC5A CALCR CALCR CBLC CBLC WFIKKN1 WFIKKN1 NCAPG2 NCAPG2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SOCS5Suppressor of cytokine signaling 5. (536 aa)
LYPD6LY6/PLAUR domain containing 6. (171 aa)
LYPD1LY6/PLAUR domain containing 1. (141 aa)
SOCS4Suppressor of cytokine signaling 4. (440 aa)
ZGPATZinc finger CCCH-type and G-patch domain containing. (510 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
DKK4Dickkopf WNT signaling pathway inhibitor 4. (224 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (348 aa)
CNRIP1Cannabinoid receptor interacting protein 1. (164 aa)
FSTFollistatin. (344 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
LRPAP1LDL receptor related protein associated protein 1. (358 aa)
LY6HLymphocyte antigen 6 family member H. (161 aa)
PXDNPeroxidasin. (1479 aa)
CBLCbl proto-oncogene. (907 aa)
LYNX1Ly6/neurotoxin 1. (118 aa)
ADH7Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide. (394 aa)
IGSF1Immunoglobulin superfamily member 1. (1354 aa)
RAMP3Receptor activity modifying protein 3. (151 aa)
PPARAPeroxisome proliferator activated receptor alpha. (467 aa)
DKK2Dickkopf WNT signaling pathway inhibitor 2. (259 aa)
CLEC12BC-type lectin domain family 12 member B. (232 aa)
CBLBCbl proto-oncogene B. (961 aa)
VPS25Vacuolar protein sorting 25 homolog. (176 aa)
SLC6A9Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (706 aa)
LYNX1-SLURP2LYNX1-SLURP2 readthrough. (97 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9; Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway. May prevent the recycling of LDLR from endosomes to [...] (811 aa)
LYPD6BLY6/PLAUR domain containing 6B. (203 aa)
IL18BPInterleukin 18 binding protein. (207 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
CHMP6Charged multivesicular body protein 6. (223 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
ACE2Angiotensin-converting enzyme. (805 aa)
SPINT3Serine peptidase inhibitor, Kunitz type 3. (89 aa)
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (576 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
IL36RNInterleukin-1. (155 aa)
ZFYVE28Zinc finger FYVE-type containing 28. (888 aa)
DKK3Dickkopf WNT signaling pathway inhibitor 3. (350 aa)
DKKL1Dickkopf like acrosomal protein 1. (242 aa)
EPHB2EPH receptor B2. (1063 aa)
TSG101Tumor susceptibility 101. (390 aa)
IL1RNInterleukin-1. (179 aa)
FAM72AUncharacterized protein. (149 aa)
GPRC5AG protein-coupled receptor class C group 5 member A. (355 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (517 aa)
CBLCCbl proto-oncogene C. (388 aa)
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (548 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1157 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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