47 items (Macaca nemestrina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FADD	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
	STK39	Serine/threonine kinase 39. (550 aa)
	AIRE	Autoimmune regulator. (542 aa)
	ECM1	Extracellular matrix protein 1. (540 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (419 aa)
	S100A7L2	S100 calcium binding protein A7 like 2. (107 aa)
	ABL1	Tyrosine-protein kinase. (1148 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (788 aa)
	CXCL12	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
	S100A7A	Protein S100; Belongs to the S-100 family. (101 aa)
	WNK1	OSR1_C domain-containing protein. (2398 aa)
	ADAM17	ADAM metallopeptidase domain 17. (803 aa)
	LOC105463814	Protein kinase domain-containing protein. (393 aa)
	RIPK3	Receptor interacting serine/threonine kinase 3. (518 aa)
	SPNS2	Sphingolipid transporter 2. (552 aa)
	TMEM102	Transmembrane protein 102. (508 aa)
	CRK	CRK proto-oncogene, adaptor protein. (304 aa)
	ENSMNEP00000035777	Apolipoprotein D. (167 aa)
	ADAM10	ADAM metallopeptidase domain 10. (748 aa)
	LRCH1	Leucine rich repeats and calponin homology domain containing 1. (768 aa)
	PYCARD	PYD and CARD domain containing. (195 aa)
	ADAM8	ADAM metallopeptidase domain 8. (824 aa)
	CCL20	C-C motif chemokine. (96 aa)
	TNFSF14	TNF superfamily member 14; Belongs to the tumor necrosis factor family. (240 aa)
	RHOA	Ras homolog family member A. (193 aa)
	CCR2	C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (374 aa)
	XCL1	SCY domain-containing protein. (114 aa)
	C10orf99	Chromosome 10 open reading frame 99. (81 aa)
	DOCK8	Dedicator of cytokinesis 8; Belongs to the DOCK family. (2096 aa)
	CCR6	C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (379 aa)
	CRKL	CRK like proto-oncogene, adaptor protein. (303 aa)
	CCL5	C-C motif chemokine. (91 aa)
	CORO1A	Coronin; Belongs to the WD repeat coronin family. (461 aa)
	CXCL13	C-X-C motif chemokine. (109 aa)
	ABL2	Tyrosine-protein kinase. (1182 aa)
	CCL21	C-C motif chemokine ligand 21. (131 aa)
	LOC105493010	SCY domain-containing protein. (114 aa)
	AIF1	Allograft inflammatory factor 1. (147 aa)
	OXSR1	Oxidative stress responsive kinase 1. (527 aa)
	CCL27	C-C motif chemokine ligand 27. (112 aa)
	ITGA4	Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
	CD99L2	CD99 molecule like 2. (261 aa)
	CXCL10	C-X-C motif chemokine 10; Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3 (By similarity); Belongs to the intercrine alpha (chemokine CxC) family. (98 aa)
	APP	Amyloid beta precursor protein. (770 aa)
	IL27RA	Interleukin 27 receptor subunit alpha. (636 aa)
	TNFRSF14	TNF receptor superfamily member 14. (280 aa)
	SPN	Sialophorin. (405 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	ABL2	ENSMNEP00000007383	ENSMNEP00000026165	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.944
ABL1	APP	ENSMNEP00000007383	ENSMNEP00000045820	Tyrosine-protein kinase.	Amyloid beta precursor protein.	0.431
ABL1	CRK	ENSMNEP00000007383	ENSMNEP00000032388	Tyrosine-protein kinase.	CRK proto-oncogene, adaptor protein.	0.992
ABL1	CRKL	ENSMNEP00000007383	ENSMNEP00000019589	Tyrosine-protein kinase.	CRK like proto-oncogene, adaptor protein.	0.999
ABL2	ABL1	ENSMNEP00000026165	ENSMNEP00000007383	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.944
ABL2	CRK	ENSMNEP00000026165	ENSMNEP00000032388	Tyrosine-protein kinase.	CRK proto-oncogene, adaptor protein.	0.984
ABL2	CRKL	ENSMNEP00000026165	ENSMNEP00000019589	Tyrosine-protein kinase.	CRK like proto-oncogene, adaptor protein.	0.998
ADAM10	ADAM17	ENSMNEP00000035871	ENSMNEP00000013691	ADAM metallopeptidase domain 10.	ADAM metallopeptidase domain 17.	0.949
ADAM10	APP	ENSMNEP00000035871	ENSMNEP00000045820	ADAM metallopeptidase domain 10.	Amyloid beta precursor protein.	0.709
ADAM17	ADAM10	ENSMNEP00000013691	ENSMNEP00000035871	ADAM metallopeptidase domain 17.	ADAM metallopeptidase domain 10.	0.949
ADAM17	APP	ENSMNEP00000013691	ENSMNEP00000045820	ADAM metallopeptidase domain 17.	Amyloid beta precursor protein.	0.467
AIF1	PYCARD	ENSMNEP00000026477	ENSMNEP00000036486	Allograft inflammatory factor 1.	PYD and CARD domain containing.	0.576
APP	ABL1	ENSMNEP00000045820	ENSMNEP00000007383	Amyloid beta precursor protein.	Tyrosine-protein kinase.	0.431
APP	ADAM10	ENSMNEP00000045820	ENSMNEP00000035871	Amyloid beta precursor protein.	ADAM metallopeptidase domain 10.	0.709
APP	ADAM17	ENSMNEP00000045820	ENSMNEP00000013691	Amyloid beta precursor protein.	ADAM metallopeptidase domain 17.	0.467
CCL20	CCL21	ENSMNEP00000037448	ENSMNEP00000043476	C-C motif chemokine.	C-C motif chemokine ligand 21.	0.714
CCL20	CCL27	ENSMNEP00000037448	ENSMNEP00000043107	C-C motif chemokine.	C-C motif chemokine ligand 27.	0.457
CCL20	CCL5	ENSMNEP00000037448	ENSMNEP00000021616	C-C motif chemokine.	C-C motif chemokine.	0.965
CCL20	CCR2	ENSMNEP00000037448	ENSMNEP00000038872	C-C motif chemokine.	C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.760
CCL20	CCR6	ENSMNEP00000037448	ENSMNEP00000019461	C-C motif chemokine.	C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family.	0.956