41 items (Macaca nemestrina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	JSRP1	Junctional sarcoplasmic reticulum protein 1. (333 aa)
	STRIT1	Small transmembrane regulator of ion transport 1. (35 aa)
	AKAP6	A-kinase anchoring protein 6. (2319 aa)
	TRDN	Triadin. (725 aa)
	CHERP	Calcium homeostasis endoplasmic reticulum protein. (927 aa)
	RYR1	Ryanodine receptor 1. (4913 aa)
	RNF175	Ring finger protein 175. (328 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
	CAMK2D	Calcium/calmodulin dependent protein kinase II delta. (533 aa)
	REEP5	Receptor expression-enhancing protein. (193 aa)
	FKBP1B	Peptidylprolyl isomerase. (108 aa)
	TMEM38A	Transmembrane protein 38A. (299 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
	JPH1	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (661 aa)
	ATP2A3	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1037 aa)
	CAMK2G	Calcium/calmodulin dependent protein kinase II gamma. (556 aa)
	ENSMNEP00000034665	Uncharacterized protein. (98 aa)
	ART1	NAD(P)(+)--arginine ADP-ribosyltransferase. (361 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
	FKBP1A	Peptidylprolyl isomerase. (108 aa)
	DMPK	DM1 protein kinase. (630 aa)
	STIM1	Stromal interaction molecule 1. (790 aa)
	PLN	Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
	RNF121	Ring finger protein 121. (327 aa)
	RYR2	Ryanodine receptor 2. (4951 aa)
	MRLN	Myoregulin. (46 aa)
	ENSMNEP00000008721	Peptidylprolyl isomerase. (106 aa)
	SLN	Uncharacterized protein. (31 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
	ATP2A1	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1030 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	KLHL41	Kelch like family member 41. (544 aa)
	SRL	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1016 aa)
	RYR3	Ryanodine receptor 3. (4856 aa)
	ASPHD1	Aspartate beta-hydroxylase domain containing 1. (377 aa)
	ATP2A2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
	TMEM38B	Transmembrane protein 38B. (291 aa)
	ASPHD2	Aspartate beta-hydroxylase domain containing 2. (369 aa)
	ASPH	Aspartate beta-hydroxylase. (762 aa)
	SRI	Sorcin. (198 aa)
	ENSMNEP00000010221	Peptidylprolyl isomerase. (130 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKAP6	FKBP1B	ENSMNEP00000033237	ENSMNEP00000044275	A-kinase anchoring protein 6.	Peptidylprolyl isomerase.	0.503
AKAP6	PRKACA	ENSMNEP00000033237	ENSMNEP00000041404	A-kinase anchoring protein 6.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.417
AKAP6	PRKACB	ENSMNEP00000033237	ENSMNEP00000031679	A-kinase anchoring protein 6.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.534
AKAP6	RYR2	ENSMNEP00000033237	ENSMNEP00000002380	A-kinase anchoring protein 6.	Ryanodine receptor 2.	0.632
ASPH	ENSMNEP00000008721	ENSMNEP00000011612	ENSMNEP00000008721	Aspartate beta-hydroxylase.	Peptidylprolyl isomerase.	0.451
ASPH	ENSMNEP00000010221	ENSMNEP00000011612	ENSMNEP00000010221	Aspartate beta-hydroxylase.	Peptidylprolyl isomerase.	0.451
ASPH	FKBP1A	ENSMNEP00000011612	ENSMNEP00000027827	Aspartate beta-hydroxylase.	Peptidylprolyl isomerase.	0.451
ASPH	FKBP1B	ENSMNEP00000011612	ENSMNEP00000044275	Aspartate beta-hydroxylase.	Peptidylprolyl isomerase.	0.649
ASPH	RYR1	ENSMNEP00000011612	ENSMNEP00000022578	Aspartate beta-hydroxylase.	Ryanodine receptor 1.	0.915
ASPH	RYR2	ENSMNEP00000011612	ENSMNEP00000002380	Aspartate beta-hydroxylase.	Ryanodine receptor 2.	0.938
ASPH	RYR3	ENSMNEP00000011612	ENSMNEP00000015878	Aspartate beta-hydroxylase.	Ryanodine receptor 3.	0.874
ASPH	TRDN	ENSMNEP00000011612	ENSMNEP00000023485	Aspartate beta-hydroxylase.	Triadin.	0.885
ATP2A1	ATP2A2	ENSMNEP00000031123	ENSMNEP00000015481	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.897
ATP2A1	ATP2A3	ENSMNEP00000031123	ENSMNEP00000037532	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.890
ATP2A1	PLN	ENSMNEP00000031123	ENSMNEP00000000944	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.	0.977
ATP2A1	RYR1	ENSMNEP00000031123	ENSMNEP00000022578	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Ryanodine receptor 1.	0.565
ATP2A1	SLN	ENSMNEP00000031123	ENSMNEP00000005925	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Uncharacterized protein.	0.877
ATP2A1	SRL	ENSMNEP00000031123	ENSMNEP00000004132	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.664
ATP2A2	ATP2A1	ENSMNEP00000015481	ENSMNEP00000031123	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.897
ATP2A2	ATP2A3	ENSMNEP00000015481	ENSMNEP00000037532	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.919