STRINGSTRING
DGKI DGKI PRKD1 PRKD1 CIT CIT RASGRP2 RASGRP2 BRAF BRAF PRKCB PRKCB PRKCQ PRKCQ MYO9A MYO9A VAV3 VAV3 KSR1 KSR1 RASSF1 RASSF1 ARHGEF2 ARHGEF2 TNS2 TNS2 NSMCE1 NSMCE1 ARHGEF28 ARHGEF28 ARHGAP29 ARHGAP29 ARAF ARAF PRKCE PRKCE DGKB DGKB DEF8 DEF8 RASGRP1 RASGRP1 CHN1 CHN1 DGKQ DGKQ PLEKHM1 PLEKHM1 DGKA DGKA VAV1 VAV1 RASGRP3 RASGRP3 DGKK DGKK CHN2 CHN2 DGKE DGKE RASSF5 RASSF5 CDC42BPA CDC42BPA RASGRP4 RASGRP4 STAC3 STAC3 VAV2 VAV2 PRKD3 PRKD3 UNC13B UNC13B AKAP13 AKAP13 PRKCA PRKCA PRKCG PRKCG ROCK1 ROCK1 PRKCZ PRKCZ CDC42BPB CDC42BPB DGKH DGKH CDC42BPG CDC42BPG UNC13C UNC13C PRKD2 PRKD2 DGKG DGKG PRKCD PRKCD STAC2 STAC2 RAF1 RAF1 STAC STAC PRKCH PRKCH ARHGAP45 ARHGAP45 GMIP GMIP DGKZ DGKZ PRKCI PRKCI KSR2 KSR2 UNC13A UNC13A RACGAP1 RACGAP1 ROCK2 ROCK2 DGKD DGKD MYO9B MYO9B PDZD8 PDZD8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DGKIDiacylglycerol kinase. (1079 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (892 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2069 aa)
RASGRP2RAS guanyl releasing protein 2. (771 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (763 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
MYO9AMyosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2555 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
KSR1Kinase suppressor of ras 1. (932 aa)
RASSF1Ras association domain family member 1. (340 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (1003 aa)
TNS2Tensin 2. (1432 aa)
NSMCE1NSE1 homolog, SMC5-SMC6 complex component. (266 aa)
ARHGEF28Rho guanine nucleotide exchange factor 28. (1729 aa)
ARHGAP29Rho GTPase activating protein 29. (1266 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (606 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
DGKBDiacylglycerol kinase. (803 aa)
DEF8Differentially expressed in FDCP 8 homolog. (463 aa)
RASGRP1RAS guanyl releasing protein 1. (832 aa)
CHN1Chimaerin; GTPase-activating protein for p21-rac. (459 aa)
DGKQDiacylglycerol kinase. (957 aa)
PLEKHM1Pleckstrin homology and RUN domain containing M1. (1055 aa)
DGKADiacylglycerol kinase. (735 aa)
VAV1Vav guanine nucleotide exchange factor 1. (846 aa)
RASGRP3RAS guanyl releasing protein 3. (734 aa)
DGKKDiacylglycerol kinase. (1265 aa)
CHN2Chimaerin; GTPase-activating protein for p21-rac. (468 aa)
DGKEDiacylglycerol kinase. (567 aa)
RASSF5Ras association domain family member 5. (418 aa)
CDC42BPANon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1732 aa)
RASGRP4RAS guanyl releasing protein 4. (673 aa)
STAC3SH3 and cysteine rich domain 3. (364 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
PRKD3Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (887 aa)
UNC13BUncharacterized protein. (4339 aa)
AKAP13A-kinase anchoring protein 13. (2830 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
CDC42BPBCDC42 binding protein kinase beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1728 aa)
DGKHDiacylglycerol kinase. (1220 aa)
CDC42BPGCDC42 binding protein kinase gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1559 aa)
UNC13CUnc-13 homolog C. (2216 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
DGKGDiacylglycerol kinase. (791 aa)
PRKCDProtein kinase C. (729 aa)
STAC2SH3 and cysteine rich domain 2. (411 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
STACSH3 and cysteine rich domain. (402 aa)
PRKCHProtein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa)
ARHGAP45Rho GTPase activating protein 45. (1148 aa)
GMIPGEM interacting protein. (974 aa)
DGKZDiacylglycerol kinase. (1172 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (690 aa)
KSR2Kinase suppressor of ras 2. (950 aa)
UNC13AUnc-13 homolog A. (1717 aa)
RACGAP1Rac GTPase activating protein 1. (632 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1474 aa)
DGKDDiacylglycerol kinase. (1216 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2135 aa)
PDZD8PDZ domain containing 8. (1154 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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