(10 nodes) Prefoldin network (Macaca nemestrina)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PFDN6	Prefoldin subunit 6. (129 aa)
	ENSMNEP00000016270	Uncharacterized protein. (494 aa)
	ENSMNEP00000017255	Uncharacterized protein. (152 aa)
	VBP1	Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (197 aa)
	UXT	Ubiquitously expressed prefoldin like chaperone. (157 aa)
	URI1	Uncharacterized protein. (537 aa)
	PFDN5	Uncharacterized protein. (160 aa)
	PFDN1	Prefoldin subunit 1. (122 aa)
	PFDN2	Prefoldin subunit 2. (154 aa)
	PFDN4	Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family. (134 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMNEP00000016270	PFDN2	ENSMNEP00000016270	ENSMNEP00000029377	Uncharacterized protein.	Prefoldin subunit 2.	0.773
ENSMNEP00000016270	PFDN4	ENSMNEP00000016270	ENSMNEP00000007042	Uncharacterized protein.	Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family.	0.421
ENSMNEP00000016270	PFDN6	ENSMNEP00000016270	ENSMNEP00000011911	Uncharacterized protein.	Prefoldin subunit 6.	0.753
ENSMNEP00000016270	UXT	ENSMNEP00000016270	ENSMNEP00000040628	Uncharacterized protein.	Ubiquitously expressed prefoldin like chaperone.	0.784
ENSMNEP00000017255	PFDN1	ENSMNEP00000017255	ENSMNEP00000030120	Uncharacterized protein.	Prefoldin subunit 1.	0.992
ENSMNEP00000017255	PFDN2	ENSMNEP00000017255	ENSMNEP00000029377	Uncharacterized protein.	Prefoldin subunit 2.	0.985
ENSMNEP00000017255	PFDN4	ENSMNEP00000017255	ENSMNEP00000007042	Uncharacterized protein.	Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family.	0.983
ENSMNEP00000017255	PFDN6	ENSMNEP00000017255	ENSMNEP00000011911	Uncharacterized protein.	Prefoldin subunit 6.	0.994
ENSMNEP00000017255	UXT	ENSMNEP00000017255	ENSMNEP00000040628	Uncharacterized protein.	Ubiquitously expressed prefoldin like chaperone.	0.485
ENSMNEP00000017255	VBP1	ENSMNEP00000017255	ENSMNEP00000003759	Uncharacterized protein.	Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family.	0.988
PFDN1	ENSMNEP00000017255	ENSMNEP00000030120	ENSMNEP00000017255	Prefoldin subunit 1.	Uncharacterized protein.	0.992
PFDN1	PFDN2	ENSMNEP00000030120	ENSMNEP00000029377	Prefoldin subunit 1.	Prefoldin subunit 2.	0.995
PFDN1	PFDN4	ENSMNEP00000030120	ENSMNEP00000007042	Prefoldin subunit 1.	Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family.	0.997
PFDN1	PFDN5	ENSMNEP00000030120	ENSMNEP00000030243	Prefoldin subunit 1.	Uncharacterized protein.	0.994
PFDN1	PFDN6	ENSMNEP00000030120	ENSMNEP00000011911	Prefoldin subunit 1.	Prefoldin subunit 6.	0.998
PFDN1	UXT	ENSMNEP00000030120	ENSMNEP00000040628	Prefoldin subunit 1.	Ubiquitously expressed prefoldin like chaperone.	0.519
PFDN1	VBP1	ENSMNEP00000030120	ENSMNEP00000003759	Prefoldin subunit 1.	Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family.	0.995
PFDN2	ENSMNEP00000016270	ENSMNEP00000029377	ENSMNEP00000016270	Prefoldin subunit 2.	Uncharacterized protein.	0.773
PFDN2	ENSMNEP00000017255	ENSMNEP00000029377	ENSMNEP00000017255	Prefoldin subunit 2.	Uncharacterized protein.	0.985
PFDN2	PFDN1	ENSMNEP00000029377	ENSMNEP00000030120	Prefoldin subunit 2.	Prefoldin subunit 1.	0.995