STRINGSTRING
DLG4 DLG4 ERAS ERAS NRG3 NRG3 WWOX WWOX LOC105475719 LOC105475719 ENSMNEP00000002753 ENSMNEP00000002753 SPARC SPARC TAB2 TAB2 ENSMNEP00000004083 ENSMNEP00000004083 EGFR EGFR NRAS NRAS STMN1 STMN1 SOS1 SOS1 NCSTN NCSTN ERBB4 ERBB4 ADAP1 ADAP1 ENSMNEP00000035304 ENSMNEP00000035304 SHC1 SHC1 FNDC3B FNDC3B EREG EREG GABRA1 GABRA1 HRAS HRAS GABRG3 GABRG3 NRG1 NRG1 PIK3R1 PIK3R1 PSENEN PSENEN NRG4 NRG4 FNDC3A FNDC3A ENSMNEP00000029690 ENSMNEP00000029690 PSEN1 PSEN1 RPS27A RPS27A GRB2 GRB2 MXD4 MXD4 PSEN2 PSEN2 WWP1 WWP1 APH1B APH1B NCOR1 NCOR1 GABRB3 GABRB3 GABRQ GABRQ BTC BTC APH1A APH1A PIK3CA PIK3CA EGF EGF ADAP2 ADAP2 ESR1 ESR1 NEDD4 NEDD4 APOE APOE UBA52 UBA52 STAT5A STAT5A ENSMNEP00000005796 ENSMNEP00000005796 ENSMNEP00000005892 ENSMNEP00000005892 PGR PGR SRC SRC ENSMNEP00000008415 ENSMNEP00000008415 ENSMNEP00000008478 ENSMNEP00000008478 GFAP GFAP GABRG2 GABRG2 CXCL12 CXCL12 GABRB2 GABRB2 HBEGF HBEGF CSN2 CSN2 NRG2 NRG2 ITCH ITCH GABRB1 GABRB1 ERBB3 ERBB3 ADAM17 ADAM17 YAP1 YAP1 ENSMNEP00000046073 ENSMNEP00000046073 CSDE1 CSDE1 KRAS KRAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (767 aa)
ERASES cell expressed Ras. (233 aa)
NRG3Neuregulin 3. (445 aa)
WWOXWW domain containing oxidoreductase. (414 aa)
LOC105475719Ubiquitin-like domain-containing protein. (127 aa)
ENSMNEP00000002753Ubiquitin-like domain-containing protein. (156 aa)
SPARCSecreted protein acidic and cysteine rich. (303 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
ENSMNEP00000004083Ubiquitin-like domain-containing protein. (127 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
STMN1Stathmin; Belongs to the stathmin family. (174 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1314 aa)
NCSTNNicastrin. (721 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
ADAP1ArfGAP with dual PH domains 1. (384 aa)
ENSMNEP00000035304Ubiquitin-like domain-containing protein. (134 aa)
SHC1SHC adaptor protein 1. (584 aa)
FNDC3BFibronectin type III domain containing 3B. (1206 aa)
EREGEpiregulin. (169 aa)
GABRA1Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (490 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
GABRG3Gamma-aminobutyric acid type A receptor gamma3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa)
NRG1Neuregulin 1. (645 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
NRG4Neuregulin 4. (121 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
ENSMNEP00000029690Uncharacterized protein. (312 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
MXD4MAX dimerization protein 4. (209 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa)
WWP1E3 ubiquitin-protein ligase. (865 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
NCOR1Nuclear receptor corepressor 1. (2442 aa)
GABRB3Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (529 aa)
GABRQGamma-aminobutyric acid type A receptor theta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (632 aa)
BTCBetacellulin. (145 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1166 aa)
ADAP2ArfGAP with dual PH domains 2. (381 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1316 aa)
APOEApolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
ENSMNEP00000005796Ribosomal_S27 domain-containing protein. (137 aa)
ENSMNEP00000005892Ubiquitin-like domain-containing protein. (156 aa)
PGRProgesterone receptor. (936 aa)
SRCTyrosine-protein kinase. (644 aa)
ENSMNEP00000008415Ubiquitin-like domain-containing protein. (83 aa)
ENSMNEP00000008478Ubiquitin-like domain-containing protein. (120 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (517 aa)
GABRG2Gamma-aminobutyric acid type A receptor gamma2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (515 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
CSN2Beta-casein; Important role in determination of the surface properties of the casein micelles. (226 aa)
NRG2Neuregulin 2. (632 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1343 aa)
ADAM17ADAM metallopeptidase domain 17. (803 aa)
YAP1Yes associated protein 1. (506 aa)
ENSMNEP00000046073Uncharacterized protein. (253 aa)
CSDE1Cold shock domain containing E1. (844 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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