STRINGSTRING
BRAF BRAF MAP2K2 MAP2K2 NTRK1 NTRK1 YWHAB YWHAB ENSMNEP00000027902 ENSMNEP00000027902 NGF NGF FRS2 FRS2 CRKL CRKL ENSMNEP00000016378 ENSMNEP00000016378 MAPK3 MAPK3 RAP1A RAP1A MAPK1 MAPK1 RAPGEF1 RAPGEF1 MAP2K1 MAP2K1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BRAFB-Raf proto-oncogene, serine/threonine kinase. (763 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
ENSMNEP00000027902Protein kinase domain-containing protein. (365 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (123 aa)
FRS2Fibroblast growth factor receptor substrate 2. (515 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
ENSMNEP00000016378Protein kinase domain-containing protein. (652 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1265 aa)
MAP2K1Mitogen-activated protein kinase kinase 1. (361 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
Server load: low (20%) [HD]