STRINGSTRING
MAPK3 MAPK3 MAPKAPK3 MAPKAPK3 RAP1A RAP1A MAPK11 MAPK11 MAPK1 MAPK1 RAPGEF1 RAPGEF1 RALA RALA MAP2K1 MAP2K1 SRC SRC BRAF BRAF NKPD1 NKPD1 ERAS ERAS MAPK13 MAPK13 SHC2 SHC2 SHC1 SHC1 RIT1 RIT1 CRK CRK HRAS HRAS YWHAB YWHAB RIT2 RIT2 ENSMNEP00000027902 ENSMNEP00000027902 NGF NGF GRB2 GRB2 SHC3 SHC3 MAPK12 MAPK12 RALB RALB NTRK1 NTRK1 SOS1 SOS1 MAP2K2 MAP2K2 MAPKAPK2 MAPKAPK2 KIDINS220 KIDINS220 RALGDS RALGDS NRAS NRAS KRAS KRAS MAPK14 MAPK14 CSDE1 CSDE1 FRS2 FRS2 SHC4 SHC4 CRKL CRKL ENSMNEP00000016378 ENSMNEP00000016378
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (382 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
MAPK11Mitogen-activated protein kinase. (366 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1265 aa)
RALARAS like proto-oncogene A. (206 aa)
MAP2K1Mitogen-activated protein kinase kinase 1. (361 aa)
SRCTyrosine-protein kinase. (644 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (763 aa)
NKPD1NTPase KAP family P-loop domain containing 1. (611 aa)
ERASES cell expressed Ras. (233 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
SHC2Uncharacterized protein. (572 aa)
SHC1SHC adaptor protein 1. (584 aa)
RIT1Ras like without CAAX 1. (219 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
RIT2Ras like without CAAX 2. (217 aa)
ENSMNEP00000027902Protein kinase domain-containing protein. (365 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (123 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
SHC3SHC adaptor protein 3. (598 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
RALBRAS like proto-oncogene B. (212 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1314 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (383 aa)
KIDINS220Kinase D interacting substrate 220. (1771 aa)
RALGDSUncharacterized protein. (909 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
CSDE1Cold shock domain containing E1. (844 aa)
FRS2Fibroblast growth factor receptor substrate 2. (515 aa)
SHC4SHC adaptor protein 4. (630 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
ENSMNEP00000016378Protein kinase domain-containing protein. (652 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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