STRINGSTRING
ENSMNEP00000041258 ENSMNEP00000041258 PPP2CA PPP2CA LEF1 LEF1 APC APC ENSMNEP00000042218 ENSMNEP00000042218 ENSMNEP00000042381 ENSMNEP00000042381 BTRC BTRC TCF7 TCF7 PPP2R5A PPP2R5A ENSMNEP00000042738 ENSMNEP00000042738 PSMB5 PSMB5 PSMC3 PSMC3 PPP2R1A PPP2R1A PSMB8 PSMB8 TLE1 TLE1 ENSMNEP00000002753 ENSMNEP00000002753 LOC105475719 LOC105475719 PSMA6 PSMA6 PSMD7 PSMD7 FRAT2 FRAT2 PSMA1 PSMA1 CTNNB1 CTNNB1 PSME3 PSME3 ENSMNEP00000000174 ENSMNEP00000000174 TCF7L1 TCF7L1 ENSMNEP00000021101 ENSMNEP00000021101 CSNK1A1L CSNK1A1L PPP2R5D PPP2R5D PSMA5 PSMA5 ENSMNEP00000019162 ENSMNEP00000019162 APC2 APC2 UBA52 UBA52 ENSMNEP00000017273 ENSMNEP00000017273 ENSMNEP00000017045 ENSMNEP00000017045 TLE6 TLE6 PSMD11 PSMD11 SKP1 SKP1 PSMD12 PSMD12 ENSMNEP00000016650 ENSMNEP00000016650 PSMD3 PSMD3 ENSMNEP00000015951 ENSMNEP00000015951 PSMD8 PSMD8 AMER1 AMER1 ENSMNEP00000013845 ENSMNEP00000013845 PSME2 PSME2 LOC105466285 LOC105466285 PSMD9 PSMD9 PSME4 PSME4 ENSMNEP00000011567 ENSMNEP00000011567 PSMC4 PSMC4 ZRANB1 ZRANB1 FRAT1 FRAT1 ENSMNEP00000010989 ENSMNEP00000010989 PSMA8 PSMA8 ENSMNEP00000010116 ENSMNEP00000010116 ENSMNEP00000008478 ENSMNEP00000008478 ENSMNEP00000008415 ENSMNEP00000008415 PSMB4 PSMB4 PSMB10 PSMB10 ENSMNEP00000007573 ENSMNEP00000007573 PSMD6 PSMD6 PSME1 PSME1 ENSMNEP00000007101 ENSMNEP00000007101 PSMA7 PSMA7 GSK3B GSK3B ENSMNEP00000005892 ENSMNEP00000005892 ENSMNEP00000005796 ENSMNEP00000005796 ENSMNEP00000004441 ENSMNEP00000004441 PSMD1 PSMD1 ENSMNEP00000004092 ENSMNEP00000004092 ENSMNEP00000004083 ENSMNEP00000004083 PSMC2 PSMC2 TLE5 TLE5 PSMB1 PSMB1 PSMB7 PSMB7 ENSMNEP00000022472 ENSMNEP00000022472 PPP2R5C PPP2R5C PSMB6 PSMB6 ENSMNEP00000023008 ENSMNEP00000023008 PSMA3 PSMA3 CUL1 CUL1 PPP2R1B PPP2R1B PSMC5 PSMC5 CSNK1A1 CSNK1A1 PSMD2 PSMD2 PSMA4 PSMA4 TLE3 TLE3 HDAC1 HDAC1 TLE2 TLE2 RPS27A RPS27A PSMB3 PSMB3 PSMD14 PSMD14 PPP2R5E PPP2R5E CTBP1 CTBP1 PPP2R5B PPP2R5B RBX1 RBX1 PSMB9 PSMB9 ENSMNEP00000031398 ENSMNEP00000031398 TCF7L2 TCF7L2 PSMC1 PSMC1 PSMD13 PSMD13 PSMD5 PSMD5 ENSMNEP00000035304 ENSMNEP00000035304 ENSMNEP00000036101 ENSMNEP00000036101 PSMF1 PSMF1 ENSMNEP00000036869 ENSMNEP00000036869 AXIN1 AXIN1 TLE4 TLE4 ENSMNEP00000038934 ENSMNEP00000038934 PSMB2 PSMB2 PSMD4 PSMD4 PPP2CB PPP2CB PSMA2 PSMA2 CTBP2 CTBP2 PSMD10 PSMD10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMNEP00000041258Prot_ATP_ID_OB domain-containing protein. (166 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
APCAPC regulator of WNT signaling pathway. (2864 aa)
ENSMNEP00000042218Uncharacterized protein; Belongs to the SKP1 family. (171 aa)
ENSMNEP00000042381Uncharacterized protein. (312 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
TCF7Transcription factor 7. (496 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
ENSMNEP00000042738Uncharacterized protein. (394 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (446 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
PSMB8Proteasome subunit beta. (276 aa)
TLE1TLE family member 1, transcriptional corepressor. (779 aa)
ENSMNEP00000002753Ubiquitin-like domain-containing protein. (156 aa)
LOC105475719Ubiquitin-like domain-containing protein. (127 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
FRAT2FRAT regulator of WNT signaling pathway 2. (233 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
CTNNB1Catenin beta 1. (781 aa)
PSME3Proteasome activator subunit 3. (265 aa)
ENSMNEP00000000174AAA domain-containing protein; Belongs to the AAA ATPase family. (414 aa)
TCF7L1Transcription factor 7 like 1. (589 aa)
ENSMNEP00000021101Zf-rbx1 domain-containing protein. (93 aa)
CSNK1A1LCasein kinase 1 alpha 1 like. (243 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
ENSMNEP00000019162AAA domain-containing protein; Belongs to the AAA ATPase family. (393 aa)
APC2APC regulator of WNT signaling pathway 2. (2301 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
ENSMNEP00000017273Protein kinase domain-containing protein. (311 aa)
ENSMNEP00000017045Hist_deacetyl domain-containing protein. (247 aa)
TLE6TLE family member 6, subcortical maternal complex member. (550 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
ENSMNEP00000016650Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (458 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (469 aa)
ENSMNEP00000015951Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (443 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
AMER1APC membrane recruitment protein 1. (990 aa)
ENSMNEP00000013845Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (436 aa)
PSME2Proteasome activator subunit 2. (254 aa)
LOC105466285Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (437 aa)
PSMD9PDZ domain-containing protein. (223 aa)
PSME4Proteasome activator subunit 4. (1844 aa)
ENSMNEP00000011567Uncharacterized protein; Belongs to the AAA ATPase family. (398 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
ZRANB1Zinc finger RANBP2-type containing 1. (734 aa)
FRAT1FRAT regulator of WNT signaling pathway 1. (234 aa)
ENSMNEP00000010989Proteasome endopeptidase complex. (241 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
ENSMNEP00000010116CSN8_PSD8_EIF3K domain-containing protein. (243 aa)
ENSMNEP00000008478Ubiquitin-like domain-containing protein. (120 aa)
ENSMNEP00000008415Ubiquitin-like domain-containing protein. (83 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMB10Proteasome subunit beta. (273 aa)
ENSMNEP00000007573MPN domain-containing protein. (149 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
PSME1Proteasome activator subunit 1. (249 aa)
ENSMNEP00000007101Uncharacterized protein. (191 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (400 aa)
ENSMNEP00000005892Ubiquitin-like domain-containing protein. (156 aa)
ENSMNEP00000005796Ribosomal_S27 domain-containing protein. (137 aa)
ENSMNEP0000000444126S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (788 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (851 aa)
ENSMNEP00000004092Proteasome subunit alpha type. (231 aa)
ENSMNEP00000004083Ubiquitin-like domain-containing protein. (127 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (468 aa)
TLE5TLE family member 5, transcriptional modulator. (264 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMB7Proteasome subunit beta. (277 aa)
ENSMNEP00000022472AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (533 aa)
PSMB6Proteasome subunit beta. (285 aa)
ENSMNEP00000023008ANK_REP_REGION domain-containing protein. (159 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (667 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
CSNK1A1Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (365 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (912 aa)
PSMA4Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (307 aa)
TLE3TLE family member 3, transcriptional corepressor. (778 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (483 aa)
TLE2TLE family member 2, transcriptional corepressor. (755 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (440 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (596 aa)
RBX1RING-type domain-containing protein. (108 aa)
PSMB9Proteasome subunit beta. (219 aa)
ENSMNEP00000031398Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (452 aa)
TCF7L2Transcription factor 7 like 2. (523 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (339 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (493 aa)
ENSMNEP00000035304Ubiquitin-like domain-containing protein. (134 aa)
ENSMNEP00000036101Uncharacterized protein. (167 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
ENSMNEP00000036869Uncharacterized protein. (97 aa)
AXIN1Axin 1. (867 aa)
TLE4TLE family member 4, transcriptional corepressor. (805 aa)
ENSMNEP00000038934ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (177 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (403 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
CTBP2C-terminal binding protein 2. (987 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
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